Neuroblastoma

Neuroblastoma is cancer that arises in immature nerve cells and affects mostly infants and children.

What is Neuroblastoma?

Neuroblastoma is a rare childhood cancer that develops from immature nerve cells called neuroblasts.

Latest Neuroblastoma News and Research

Ketone body β-hydroxybutyrate restores protein balance and targets Alzheimer’s-linked aggregates

Scientists identify β-hydroxybutyrate as a key regulator of protein solubility, offering a novel pathway to combat neurodegeneration in aging and Alzheimer’s disease.

4 Dec 2024

Leveraging genetic variations for more effective cancer therapies

By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups.

14 Nov 2024

CAR T cell therapy breakthroughs bring new hope for treating solid tumors

Researchers advance CAR T cell therapy for solid tumors by innovating ways to overcome the unique barriers of solid tumor environments, with promising clinical results.

13 Nov 2024

Single-cell study identifies pro-metastatic cell subpopulations

Neuroblastoma (NB), the most prevalent extracranial solid tumor in children, poses a significant therapeutic challenge due to its metastasis and high heterogeneity. A recent study leveraging single-cell RNA sequencing (scRNA-seq) has uncovered vital molecular mechanisms underlying NB's progression and metastasis, shedding light on potential therapeutic targets.

3 Nov 2024

SU2C announces grants to support cutting-edge research in a variety of cancers

Stand Up To Cancer (SU2C) today announced grants to several teams of leading cancer investigators in support of cutting-edge research in a variety of cancers including head and neck, pediatric, pancreatic, breast, rectal and gastro-esophageal cancers, as well as research focused on how the microbiome communicates with the immune system.

15 Oct 2024

Florida breast cancer foundation funds two UCF projects to combat breast cancer

As Breast Cancer Awareness Month begins, two College of Medicine cancer researchers have received statewide grants to support their innovative projects to fight a disease that strikes one in eight American women.

3 Oct 2024

New study links pulmonary carcinoid aggressiveness to TERT gene activation

Pulmonary carcinoids are rare tumors of the lung with extremely different clinical courses. In many patients, they behave like benign tumors; surgical removal of the tumor leads to a complete cure. However, some patients experience aggressive growth and spread (metastasis) of the tumor with poor chances of recovery. The biological causes of these different forms of the disease are still unknown.

3 Oct 2024

Prenatal BPA exposure tied to autism risk in boys

Study reveals that prenatal exposure to BPA disrupts aromatase activity in male brains, potentially leading to autism-like symptoms. Treatment with 10-HDA shows promise in reversing these effects.

11 Aug 2024

Seaweed extract shows promise in protecting neurons in Parkinson’s disease

Ecklonia cava polyphenols (ECPs) show promise in reducing neuronal damage caused by rotenone in Parkinson’s disease (PD) by activating the Nrf2-ARE pathway, highlighting their potential as a neuroprotective treatment.

7 Aug 2024

WEHI spinout aims to revolutionize the development of cancer drugs

Australia has cemented its role in becoming a major player in the next generation of medicines with the launch of Ternarx – a globally competitive biotechnology company dedicated to finding new treatments for hard-to-treat cancers.

20 Jun 2024

Scientists discover new insight into the genetic pathway of neuroblastoma

Scientists have discovered a new insight into the genetic pathway of childhood cancer, offering new hope for tailored treatments.

15 May 2024

Curcuminoid compounds show promise against COVID-19 in neuronal cells

The effects of curcumin and curcuminoids on a human neuroblastoma cell line (SH-SY5Y) infected with SARS-CoV-2.

14 May 2024

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.

9 May 2024

NCCN 2024 Annual Conference focuses on practical applications for improving cancer care

The National Comprehensive Cancer Network (NCCN)-;an alliance of leading cancer centers-;hosted more than 1,700 oncology professionals during the NCCN 2024 Annual Conference on April 5-7.

13 Apr 2024

Longer durations of breastfeeding lowers the risk of childhood cancers

Whether duration of breastfeeding was associated with a lower risk of childhood cancers.

28 Mar 2024

BU study reveals key to combating high-risk neuroblastoma

The MYCN oncoprotein (proteins related to the growth of cancer cells) plays a key role in starting, advancing and making it difficult to treat various human cancers.

15 Mar 2024

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

The therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) from olive oil.

15 Mar 2024

Research project receives 25 million U.S. dollars to develop drugs against childhood cancers

Cancer is one of the most common causes of death in children worldwide. A research team in which the University of Würzburg is involved wants to change this – and has now received substantial funding for its work.

6 Mar 2024

Universal, essential biomarker identified for childhood neuroblastoma

Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma – and a potential new target for treatment.

27 Feb 2024

Olive oil's secret weapon against Alzheimer's: phenolic compounds

A comprehensive review in the International Journal of Molecular Sciences highlights the potential of extra-virgin olive oil and its phenolic compounds in preventing and treating Alzheimer's disease through various mechanisms, including reducing amyloid-beta accumulation and neuroinflammation.

12 Feb 2024