Osteoarthritis News and Research

Latest Osteoarthritis News and Research

Kitov announces more data from Phase III trial on the favorable blood pressure effects of KIT-302

Kitov Pharmaceuticals, an innovative biopharmaceutical company focused on late-stage drug development, today announced more data from its successfully concluded Phase III trial for its lead drug candidate, KIT-302. Data showed the favorable blood pressure effects of KIT-302 were present in all blood pressure variables measured in the study.

18 Dec 2015

Kitov Pharmaceuticals' KIT-302 drug candidate meets primary efficacy endpoint in Phase III clinical trial

Kitov Pharmaceuticals, an innovative biopharmaceutical company focused on late-stage drug development, announced today that the Phase III, double-blind, placebo-controlled clinical trial for its leading drug candidate, KIT-302, successfully met the primary efficacy endpoint of the trial protocol as approved by the U.S. Food & Drug Administration (FDA).

15 Dec 2015

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

Researchers from the University of Arkansas for Medical Sciences and other institutions are reporting the discovery of the first broad spectrum drug that can potently kill senescent (or aging) cells in culture and effectively clear the cells in animals by specifically targeting a pathway that is critical for the survival of senescent cells.

15 Dec 2015

Human body clock study paves way for drug treatment of osteoarthritis

A University of Manchester biologist has for the first time established that the painful and debilitating symptoms endured by osteoarthritis sufferers are intrinsically linked to the human body clock.

15 Dec 2015

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

In the majority of cases, hip x-rays are not reliable for diagnosing hip osteoarthritis (OA), and can delay the treatment of this debilitating disease.

9 Dec 2015

Alleviating big toe joint pain in patients

Prefabricated foot orthoses and rocker-sole footwear (in which the sole of the shoe is curved) are effective at reducing peak pressure under the big toe in people with a condition called first metatarsophalangeal joint osteoarthritis, but new research shows that they achieve this through different mechanisms.

8 Dec 2015

Weight loss can slow degeneration of knee cartilage in obese people

Obese people who lose a substantial amount of weight can significantly slow the degeneration of their knee cartilage, according to a new MRI study presented today at the annual meeting of the Radiological Society of North America.

30 Nov 2015

Study sheds new light on the controversy surrounding common osteoarthritis treatment

Injections of hyaluronic acid (HA) are a common treatment of pain in osteoarthritis of the knee - a condition that affects 27 million Americans according to the Centers for Disease Control and Prevention. The injections replace natural HA that has depleted from one's joints, which can cause pain and stiffness due to the lack of lubrication between bones moving against each other.

26 Nov 2015

HEAL Project aims to regenerate human knees and limbs within 15 years

On Veteran's Day the University of Connecticut announced the launch of its new grand research challenge: regeneration of a human knee within 7 years, and an entire limb within 15 years.

12 Nov 2015

Lower socioeconomic status significantly increases risk of pain following knee replacement

Non-white race and lack of education are known risk factors for pain and poorer function after knee replacement surgery. What isn't clear is how a community's poverty level affects the outcomes of having a joint replaced. Findings from a new study conducted by researchers from Hospital for Special Surgery suggest that lower socioeconomic status at the community level significantly increases the risk of pain and poor function following a knee replacement.

10 Nov 2015

New review finds scant scientific evidence supporting use of cannabinoids in rheumatic diseases

Although there are anecdotal reports indicating that cannabinoids, especially marijuana (or herbal cannabis), may be of therapeutic benefit for some patients with rheumatic complaints, a new review published in Arthritis Care & Research, a journal of the American College of Rheumatology, finds scant scientific evidence supporting any use of cannabinoids in rheumatic diseases. Furthermore, not a single controlled study has examined herbal cannabis in the rheumatology patient population.

10 Nov 2015

Presence of tophi in people with gout can increase risk of developing cardiovascular disease

The presence of tophi - crystal deposits of uric acid found on the surface of the joints or in the skin and cartilage - in people with gout can increase their risk of developing cardiovascular disease, according to research presented this week at the American College of Rheumatology Annual Meeting in San Francisco.

9 Nov 2015

Researchers develop novel technology for chronic arthritis

Joint inflammation (arthritis) is a common problem in medical practice and can be due to a variety of causes. Many types of inflammatory disorders affecting the joints belong to the diverse group of rheumatic diseases.

6 Nov 2015

Resistance strength training reduces pain, increases function in people with hand OA

Resistance strength training reduces pain and increases function and treatment satisfaction in people with hand osteoarthritis, according to new research findings presented this week at the American College of Rheumatology Annual Meeting in San Francisco.

6 Nov 2015

Research shows why osteoarthritis and hip changes are more frequent in athletes

Osteoarthritis and reduced range of motion in the hip and groin are more common among athletes and other people who engage in strenuous physical activity. The cause may be microscopic injuries due to high load on the hips and subsequent joint changes. A PhD thesis at Sahlgrenska Academy studied elite soccer and hockey players.

5 Nov 2015

Samumed to present preclinical and clinical data on Wnt pathway for OA treatment at ACR 2015

Samumed, LLC, a leader in tissue regeneration, announced today that it will present preclinical and clinical data on a small molecule modulator of the Wnt pathway (SM04690, an investigational new drug) for potential disease modifying treatment of osteoarthritis (OA) of the knee at 2015 American College of Rheumatology Annual Meeting.

4 Nov 2015

Lithium chloride could offer effective treatment against osteoarthritis

Bioengineers from Queen Mary University of London have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells' antennae called primary cilia.

28 Oct 2015

University of Manchester scientists identify brain mechanism that raises pain threshold

Scientists at The University of Manchester have shown for the first time that the numbers of opiate receptors in the brain increases to combat severe pain in arthritis sufferers.

26 Oct 2015

Minimally invasive implant procedure effective for patients with sacroiliac joint dysfunction

A minimally invasive implant procedure is highly effective in reducing pain and disability for patients with sacroiliac joint (SIJ) dysfunction, reports a clinical trial in the November issue of Neurosurgery, official journal of the Congress of Neurological Surgeons, published by Wolters Kluwer.

23 Oct 2015

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Ember Therapeutics, Inc., a privately held, New York-based biopharmaceutical company that is developing targeted therapies for osteoarthritis, kidney fibrosis, and other indications using Bone Morphogenetic Protein (BMP)-7, announced today initial results from the Phase II(a) trial of local BMP-7 administration in patients with moderate osteoarthritis of the knee.

20 Oct 2015

Osteoarthritis News and Research

Latest Osteoarthritis News and Research

Kitov announces more data from Phase III trial on the favorable blood pressure effects of KIT-302

Kitov Pharmaceuticals' KIT-302 drug candidate meets primary efficacy endpoint in Phase III clinical trial

Researchers discover first broad spectrum drug that can potently kill aging cells in culture

Human body clock study paves way for drug treatment of osteoarthritis

X-rays not reliable for diagnosing hip osteoarthritis in majority of cases

Alleviating big toe joint pain in patients

Weight loss can slow degeneration of knee cartilage in obese people

Study sheds new light on the controversy surrounding common osteoarthritis treatment

HEAL Project aims to regenerate human knees and limbs within 15 years

Lower socioeconomic status significantly increases risk of pain following knee replacement

New review finds scant scientific evidence supporting use of cannabinoids in rheumatic diseases

Presence of tophi in people with gout can increase risk of developing cardiovascular disease

Researchers develop novel technology for chronic arthritis

Resistance strength training reduces pain, increases function in people with hand OA

Research shows why osteoarthritis and hip changes are more frequent in athletes

Samumed to present preclinical and clinical data on Wnt pathway for OA treatment at ACR 2015

Lithium chloride could offer effective treatment against osteoarthritis

University of Manchester scientists identify brain mechanism that raises pain threshold

Minimally invasive implant procedure effective for patients with sacroiliac joint dysfunction

Ember Therapeutics reports initial results from BMP-7 Phase II trial in patients with moderate osteoarthritis of the knee

Innovation in neuroscience drug discovery - eBook eBook

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Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Osteoarthritis News and Research

Latest Osteoarthritis News and Research

Innovation in neuroscience drug discovery - eBook eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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