Osteoarthritis

According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.

What is Osteoarthritis?

Osteoarthritis is a degenerative joint disease that involves the degradation of joints, articular cartilage, and subchondral bone as a result of mechanical stress.

Osteoarthritis Causes

Osteoarthritis Diagnosis

Osteoarthritis Treatments

Osteoarthritis Symptoms

Osteoarthritis Types

Living with Osteoarthritis

Causes of Hand Pain

Osteoarthritis and Diet

Osteoarthritis Triggers

Turmeric for Osteoarthritis

Osteoarthritis Complications

See more featured articles »

Should You Exercise With Osteoarthritis?

Easing Hand Pain in Osteoarthritis

Natural Ways to Ease Osteoarthritis Pain

Supplements for Osteoarthritis

Latest Osteoarthritis News and Research

First 'blueprint' of human skeletal development offers new insights into bone formation

The first 'blueprint' of human skeletal development reveals how the skeleton forms, shedding light on the process of arthritis, and highlighting cells involved in conditions that affect skull and bone growth.

21 Nov 2024

BMI's influence on disease pathogenesis uncovered in new research

The study highlights BMI's role in mediating genetic risk for diseases, suggesting a complex relationship with conditions like heart failure and osteoarthritis.

14 Nov 2024

Genetic links between osteoarthritis and cardiovascular disease reveal hidden common risks

Shared genetic factors may drive both osteoarthritis and cardiovascular disease, suggesting a common genetic basis that influences the development of these diseases.

10 Nov 2024

Research identifies best materials for long-lasting hip implants

Hip implants with a delta ceramic or oxidized zirconium head and highly crosslinked polyethylene liner or cup had the lowest risk of revision during the 15 years after surgery, a new study led by the University of Bristol has found.

8 Nov 2024

Adipo Therapeutics shares results of studies on potential obesity treatment

Adipo Therapeutics LLC, a late-stage, preclinical biopharmaceutical company developing a potential treatment for obesity and related metabolic disorders, presented data from two studies at the annual meeting of The Obesity Society in San Antonio.

7 Nov 2024

Knee replacement surgery outcomes improve with native alignment approach

When performing knee replacement surgery, also called total knee arthroplasty, doctors traditionally try to align the hip, knee, and ankle in a straight line, forming a neutral alignment, rather than replicating the patient's original alignment.

4 Nov 2024

Weight loss drug semaglutide may offer relief for knee arthritis pain

Semaglutide shows promise in treating knee osteoarthritis by reducing pain and weight, offering a safe alternative to traditional pharmacological interventions.

4 Nov 2024

Scientists develop color-coded X-rays to detect early disease

Medical imaging is no longer in Kansas, Toto, as a team led by Penn State researchers brings traditional black and white diagnostic images of X-rays and traditional CT scans into technicolor. The researchers developed novel contrast agents that target two proteins implicated in osteoarthritis, a degenerative joint disease commonly characterized as wear-and-tear arthritis.

30 Oct 2024

Repeated fasting for multiple orthopedic surgeries linked to poor recovery outcomes

People who have multiple orthopedic surgeries during the same hospital stay are more likely to suffer malnutrition due to repeated or prolonged fasting, which can slow recovery and increase the risk of death, according to a study of more than 28 million patients presented at the ANESTHESIOLOGY 2024 annual meeting.

20 Oct 2024

Novel method boosts MSC efficacy for articular cartilage repair

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, alongside collaborators from the National University of Singapore Tissue Engineering Programme (NUSTEP), have developed a novel method to enhance the ability of mesenchymal stromal cells (MSCs) to generate cartilage tissue by adding ascorbic acid (AA) during MSC expansion.

18 Oct 2024

Shift Bioscience raises $16 M to advance cell simulation AI platform

Shift Bioscience is a biotech company using generative AI models to understand how activation of different genes can reverse the aging process. This research is a fundamental step forward in designing more effective drugs to treat age-related diseases.

From Shift Bioscience 16 Oct 2024

New gene therapy offers hope in combatting childhood obesity

According to the Centers for Disease Control, nearly 20% of children and teens are considered obese.

14 Oct 2024

Novel antibody shows promise for pain relief in peripheral nerves

Cell surface proteins play a crucial role in cell communication and in sensing changes in the extracellular environment.

9 Oct 2024

Overcoming CRISPR's side effects for therapeutic applications

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism. It's a reagent-;a substance that facilitates a reaction-;that combines an enzyme with a programmable RNA capable of locating specific genetic sequences. Once guided to the correct spot, the enzyme acts like a pair of scissors, cutting, replacing, or deleting sequences of DNA.

7 Oct 2024

Plant polyphenols: The secret to living longer and healthy aging?

Plant polyphenols show promise in combating aging, supporting mitochondrial health and reducing inflammation, potentially improving quality of life for seniors.

2 Oct 2024

'Treating Naturally Occurring Disease’, explained by Founder, Professor Noel Fitzpatrick

Humanimal Trust advocates for studying naturally occurring diseases in animals to advance cancer and osteoarthritis treatments for both humans and animals.

27 Sep 2024

Mechanically stimulated 3D multicellular systems

To study biomechanical forces in multicellular systems, effective mechanical stimulation is an essential tool. A 3D microstructure device is developed using Two-Photon Polymerization (2PP)-based 3D printing for mimicking the human multicellular environment.

From Nanoscribe GmbH & Co. KG 18 Sep 2024