Osteoarthritis

According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.

What is Osteoarthritis?

Osteoarthritis is a degenerative joint disease that involves the degradation of joints, articular cartilage, and subchondral bone as a result of mechanical stress.

Osteoarthritis Causes

Osteoarthritis Diagnosis

Osteoarthritis Treatments

Osteoarthritis Symptoms

Osteoarthritis Types

Living with Osteoarthritis

Causes of Hand Pain

Osteoarthritis and Diet

Osteoarthritis Triggers

Turmeric for Osteoarthritis

Osteoarthritis Complications

See more featured articles »

Should You Exercise With Osteoarthritis?

Easing Hand Pain in Osteoarthritis

Natural Ways to Ease Osteoarthritis Pain

Supplements for Osteoarthritis

Latest Osteoarthritis News and Research

Largest study of osteoarthritis genetics uncovers new drug targets

Osteoarthritis is the leading cause of disability and chronic pain worldwide, affecting an estimated 595 million people globally.

9 Apr 2025

Hydrogel-based drug delivery offers hope for post-traumatic osteoarthritis

Post-traumatic osteoarthritis (PTOA) is a condition that affects joints after an injury. Current treatments focus on relieving symptoms but do not prevent or stop the progression of the condition.

1 Apr 2025

Queen Mary scientists invent a new way to repair osteochondral defects

Scientists at Queen Mary University of London have invented a new way to repair osteochondral defects – a common form of joint damage often caused by sports injuries or trauma – and to prevent progression to osteoarthritis.

1 Apr 2025

Altered knee joint movement after ACL surgery could contribute to early-onset knee osteoarthritis

Some individuals who have had anterior-cruciate-ligament reconstruction (ACLR), the kind of surgery often performed on athletes' knees, may develop early-onset knee osteoarthritis.

19 Mar 2025

Current state and future prospects of artificial ligaments for treating ACL injuries

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

14 Mar 2025

What can you do with a BioAFM instrument?

Even more answers to help understand how BioAFM can be used!

From Bruker BioAFM 14 Mar 2025

Earlier ACL surgery may reduce risk of knee osteoarthritis

A preclinical study by HSS investigators found that earlier anterior cruciate ligament (ACL) reconstruction led to lower immune cell activity, less inflammation and fewer joint changes associated with knee osteoarthritis compared to delayed surgery.

12 Mar 2025

Global trends show sharp increase in osteoarthritis among postmenopausal women

The global number of cases of osteoarthritis, as well the disability associated with the condition, have risen by more than 130% over the past 3 decades among women who have gone through the menopause, indicates a data analysis spanning 1990 to 2021, and published in the open access journal BMJ Global Health.

4 Mar 2025

Understanding obesity in pets and its health risks

Your 8-year-old chocolate Lab is putting on weight, and you know she should probably lose a pound or two. But when she looks at you pleadingly with those big brown eyes, how can you resist handing out just one more treat?

28 Feb 2025

Atlantia Clinical Trials: Investigating the interrelation of microbiology and immunology

To be decided by the editor

From Atlantia Clinical Trials 28 Feb 2025

Artificial ligaments could revolutionize ACL surgery and recovery

Anterior cruciate ligament (ACL) injuries are common, especially among athletes. Each year, over 400 000 ACL reconstruction (ACLR) surgeries are carried out globally.

27 Feb 2025

Single-cell analysis reveals key chondrocyte subpopulations in osteoarthritis

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA).

26 Feb 2025

Strontium-enhanced exosomes show promise for osteoarthritis treatment

Temporomandibular joint osteoarthritis (TMJOA) is a debilitating condition that causes severe joint pain, restricted mobility, and progressive cartilage degradation.

24 Feb 2025

Aging isn’t just in your genes—your environment plays a bigger role, study shows

Study explores the relative contributions of genetics and environmental factors to aging and premature mortality. It highlights how the exposome—lifetime environmental exposures—shapes disease risks, with socioeconomic status, smoking, and lifestyle choices emerging as key aging determinants.

23 Feb 2025

CT scans expose widespread health problems in Viking skulls

Sweden's Viking Age population appears to have suffered from severe oral and maxillofacial disease, sinus and ear infections, osteoarthritis, and much more.

22 Feb 2025

New study reveals LRP1's crucial role in bone formation and joint development

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from complex genetic and environmental interactions that disrupt bone formation and joint development.

19 Feb 2025

People with depression at higher risk for long-term physical health conditions

Adults with a history of depression gain long-term physical conditions around 30% faster than those without, according to research publishing February 13th in the open-access journal PLOS Medicine.

13 Feb 2025

Mediterranean diet boosts quality of life—here’s how

A systematic review finds that following the Mediterranean diet is linked to better physical, mental, and social well-being, particularly in aging populations and those with chronic conditions.

10 Feb 2025

AI-driven ECG age prediction transforms early disease detection

AI-enabled ECG biological age (ECG-BA) improves disease risk classification beyond chronological age, enhancing early detection of aging-related conditions like heart disease, Alzheimer’s, and cancer.

9 Feb 2025

Dysregulation of RNA-binding proteins in rheumatoid arthritis and osteoarthritis

Announcing a new publication for Acta Materia Medica journal. Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and dysregulation of RNA-binding proteins (RBPs), which are critical for alternative mRNA splicing and translational control in rheumatoid arthritis (RA).

6 Feb 2025