Osteoarthritis News and Research

Latest Osteoarthritis News and Research

Arana updates inflammatory pipeline milestones

Biotechnology company Arana Therapeutics Limited today provided an update on the major inflammatory compounds in its drug development pipeline. As part of this update, Arana said it has developed a new antibody candidate ART123, targeting inflammatory diseases and it plans to start a Phase I clinical trial for age-related macular degeneration (AMD) candidate PMX53 in 2009.

21 Sep 2008

New cannabis-like drugs could block pain without affecting brain

A new type of drug could alleviate pain in a similar way to cannabis without affecting the brain, according to a new study published in the journal Pain on Monday 15 September.

15 Sep 2008

Knee osteoarthritis a growing problem in U.S.

Almost half of all U.S. adults and nearly two-thirds of obese adults will develop painful osteoarthritis of the knee by age 85, a study based at the University of North Carolina at Chapel Hill suggests.

2 Sep 2008

Researchers find genetic proof on how osteoarthritis destroys cartilage

A team of orthopaedic researchers has found definitive, genetic proof of how the most common form of arthritis destroys joint cartilage in nearly 21 million aging Americans, according to a study published online Sept. 2 in the Journal of Bone and Mineral Research. The findings serve as an important foundation for the design of new treatments for osteoarthritis (OA), researchers said.

2 Sep 2008

Antiangiogenic and anti-inflammatory drugs: are they safe?

Since Rofecoxib (Vioxx) was withdrawn from the worldwide market based on the safety findings of the Adenomatous Polyp Prevention on Vioxx (APPROVe) study, the uncertainty around the cardiovascular safety of NSAIDs and COX-2 inhibitors remains and leaves practitioners with difficult management decisions for the hundreds of millions of patients worldwide who continue to require pain-relieving therapy to maintain an acceptable quality of life.

1 Sep 2008

NicOx updates on PF-03187207 and research collaboration with Pfizer

NicOx S.A. has announced the results of a dose-ranging phase 2 study conducted with PF‑03187207 in Japanese patients with glaucoma by its partner Pfizer Inc. PF-03187207 is a nitric oxide-donating prostaglandin analog. The study was designed to compare the safety and efficacy of several doses of PF-03187207 to Xalatan (latanoprost) and enrolled 112 Japanese patients with primary open-angle glaucoma or ocular hypertension.

25 Aug 2008

New imaging technology provides early diagnosis of osteoarthritis

A newly developed medical imaging technology may provide doctors with a long-awaited test for early diagnosis of osteoarthritis (OA), scientists from New York reported today at the 236th National Meeting of the American Chemical Society.

20 Aug 2008

Research indicates no justification for denying obese patients knee replacements

Research by scientists at the MRC Epidemiology Resource Centre at the University of Southampton, in collaboration with colleagues at the universities of Bristol, Oxford and Keele, has shown that there is no justification for denying obese patients knee replacement surgery.

20 Aug 2008

Frankincense reduces the symptoms of osteoarthritis

An enriched extract of the 'Indian Frankincense' herb Boswellia serrata has been proven to reduce the symptoms of osteoarthritis. Research published today in BioMed Central's open access journal Arthritis Research & Therapy has shown that patients taking the herbal remedy showed significant improvement in as little as seven days.

29 Jul 2008

No justification for denying obese patients knee replacement surgery

There is no justification for denying obese patients knee replacement surgery: They benefit almost as much as anyone else from the procedure, concludes a small study published ahead of print in the Annals of the Rheumatic Diseases.

23 Jul 2008

New cartilage repair gel developed by University of Bradford

The University of Bradford's School of Engineering, Design and Technology and Advanced Gel Technology Ltd (AGT), a University spin out company, are developing a cartilage repair gel to improve the quality of life for people suffering with medical joint trouble such as osteoarthritis.

22 Jul 2008

Hip or knee replacement surgery may improve osteoarthritis symptoms in older adults

Older adults who have hip or knee replacement surgery for severe osteoarthritis may take several weeks to recover but appear to have excellent long-term outcomes, according to a report in the July 14 issue of Archives of Internal Medicine.

14 Jul 2008

Young farmers may be more susceptible to degenerative skeletal disorders later in life

Although farm chores are likely to keep young boys in shape and out of trouble, University of Cincinnati (UC) environmental health experts caution that it could be harmful to overall bone health if done too often at a young age.

14 Jul 2008

60% of people in the U.S. age 18 and older have at least one chronic medical condition

About six of every 10 people in the United States age 18 and older have at least one chronic medical condition, according to the latest News and Numbers from the Agency for Healthcare Research ands Quality.

3 Jun 2008

Meniscal damage and joint malalignment predictors of cartilage loss

Marked by cartilage and bone degradation, progressive knee osteoarthritis (OA) is believed to result in part from a combination of several local mechanical factors. Lack of joint stability, poor joint alignment and injuries to the disks of meniscal tissue that cushion the knee all affect load distribution and the toll to the vulnerable OA knee.

2 Jun 2008

Acupuncture reduces pain and dysfunction in head and neck cancer patients after neck dissection

New data from a randomized, controlled trial found that acupuncture provided significant reductions in pain, dysfunction, and dry mouth in head and neck cancer patients after neck dissection. The study was led by David Pfister, MD, Chief of the Head and Neck Medical Oncology Service, and Barrie Cassileth, PhD, Chief of the Integrative Medicine Service, at Memorial Sloan-Kettering Cancer Center (MSKCC). Dr. Pfister presented the findings today at the annual meeting of the American Society for Clinical Oncology.

1 Jun 2008

Knee injuries among most costly high school sports-related injuries

Knee injuries, among the most economically costly sports injuries, are the leading cause of high school sports-related surgeries according to a study conducted at the Center for Injury Research and Policy (CIRP) of the Research Institute at Nationwide Children's Hospital and published in the June issue of The American Journal of Sports Medicine.

22 May 2008

Outcomes of obese and nonobese patients undergoing revision total hip arthroplasty

Along with age and injuries, obesity is a leading risk factor for osteoarthritis (OA), a painful and disabling joint disease. While excessive weight can aggravate the toll on almost any joint, obesity has been associated with a higher prevalence of hip OA and an increase in total hip arthroplasty (THA).

8 May 2008

Geron Corporation awarded UK grant funding for human embryonic stem cell research

Geron Corporation announced today two grant awards to the University of Edinburgh from the UK Stem Cell Foundation, with funding from the Medical Research Council and Scottish Enterprise.

6 May 2008

New tool for tissue damage assessment

A tool with the potential to determine the level of tissue damage in patients with osteo-arthritis, sports injuries and other conditions affecting bone and cartilage is being developed by QUT researchers. Professor Oloyede said that the device, which he calls a "smarthroscope", may be able to reduce the cost of surgery, eliminate unnecessary surgery, and could be useful in developing countries.

2 May 2008