Pharmacology News and Research

Latest Pharmacology News and Research

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

InSysBio continues to investigate the mechanisms underlying Alzheimer's disease using the quantitative systems pharmacology modeling approach. The part of QSP model describing tau protein was published in the PLOS ONE journal. This is one of more than dozen InSysBio publications in AD area during last seven years.

28 Feb 2018

Receptors crucial for establishing strong memories

When we create a memory, a pattern of connections forms between neurons in the brain. New work from UC Davis shows how these connections can be strengthened or weakened at a molecular level. The study is published Feb. 27 in the journal Cell Reports.

27 Feb 2018

Failed osteoarthritis drug may help lessen opioid dependence

A new study from Indiana University suggests that a drug proven safe for use in people may prevent opioid tolerance and physical dependence when used in combination with opioid-based pain medications.

27 Feb 2018

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.

27 Feb 2018

Repurposing leukemia drugs may be effective approach for treating metastatic melanoma patients

Data from a new study led by University of Kentucky Markey Cancer Center researchers shows that repurposing drugs used to treat leukemia has promise for preventing melanoma metastasis.

26 Feb 2018

University of Illinois at Chicago awarded $4.6 million NIH grant for chronic pain research

The University of Illinois at Chicago has been awarded a $4.6 million grant from the National Heart, Lung, and Blood Institute to study the molecular neurobiology of chronic pain in patients with sickle cell disease and to develop potential new drug treatments.

26 Feb 2018

New discovery may allow doctors to treat inflammation in neurodegenerative diseases

A new discovery about the immune system may allow doctors to treat harmful inflammation that damages the brain in neurodegenerative diseases such as Alzheimer's. It might also let doctors save patients from the potentially deadly inflammation of sepsis, a full-body infection that kills a quarter-million Americans every year.

26 Feb 2018

Study finds tobacco smoke exposure among most adolescents in economically disadvantaged population

Ninety-four percent of adolescents ages 13 to 19 in an economically disadvantaged, largely minority population in San Francisco had measurable levels of a biomarker specific for exposure to tobacco smoke.

23 Feb 2018

UC Riverside researchers discover way to halt cancer metastasis

A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

23 Feb 2018

Respiratory disease patients with arthritis struggle to use complex inhalers

Respiratory disease patients with arthritis could struggle to manage their conditions because their inhalers are too fiddly for them to use, University of Bath research has found.

23 Feb 2018

Beetroot may reduce kidney failure risk after heart x-ray, research reveals

Beetroot may reduce the risk of kidney failure in patients having a heart x-ray, according to research led by Queen Mary University of London.

22 Feb 2018

Pioneering study may pave way for effective painkillers to treat neuropathic pain

A pioneering international study, carried out by the University of Granada, Harvard University, the University of California, Los Angeles, the University of Florida, Laval University and the Jackson Laboratory has conducted an in-depth analysis of the molecular differences between the most common symptoms associated with neuropathic pain.

21 Feb 2018

Researchers target abnormal epigenetic mechanisms involved in childhood cancers

Several childhood cancer cell types show features of immature neural cells, and there is evidence suggesting that these tumors may arise from neural crest stem cells that underwent abnormal changes during embryonic development.

20 Feb 2018

Scientists explore connection between bad sleep habits and stiff blood vessels

What do bad sleep habits and stiff blood vessels have in common? Nothing good, say scientists exploring what appears to be a direct connection between a circadian clock that isn't working as it should and an enzyme that promotes inflammation working overtime.

20 Feb 2018

New scanning technology could reduce number of biopsies on people with fatty liver disease

A study jointly led by the University of Birmingham and University of Edinburgh has revealed that a new scanning technology could almost halve the number of liver biopsies carried out on people with fatty liver disease.

13 Feb 2018

Cannabis use triggers schizophrenia and other psychiatric issues

Schizophrenia and other psychiatric issues may be triggered by marijuana use, according to a research analysis in the Journal of the American Osteopathic Association.

12 Feb 2018

Experimental molecular therapy restores insulation on peripheral nerves in mice

When the body attacks its own healthy tissues in an autoimmune disease, peripheral nerve damage handicaps people and causes persistent neuropathic pain when insulation on healing nerves doesn't fully regenerate.

12 Feb 2018

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

At Magee-Womens Research Institute and UPMC Hillman Cancer Center, a large team of clinical and laboratory researchers dedicated to understanding treatment resistance in the most common form of breast cancer have identified a new genetic change in the estrogen receptor that contributes to therapy resistance.

7 Feb 2018

More work required to find the right drug dosage for pediatric patients

Children should not be considered 'small adults' when it comes to prescribing medications, but it can be difficult to determine the right dosage of a particular drug for young patients.

7 Feb 2018

Multinational companies continue to manufacture unapproved formulations in India, research finds

Millions of unapproved antibiotics are being sold in India, according to a new study by researchers at Queen Mary University of London and Newcastle University.

5 Feb 2018

Pharmacology News and Research

Latest Pharmacology News and Research

InSysBio evaluates tau protein phosphorylation related targets for treatment of AD

Receptors crucial for establishing strong memories

Failed osteoarthritis drug may help lessen opioid dependence

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Repurposing leukemia drugs may be effective approach for treating metastatic melanoma patients

University of Illinois at Chicago awarded $4.6 million NIH grant for chronic pain research

New discovery may allow doctors to treat inflammation in neurodegenerative diseases

Study finds tobacco smoke exposure among most adolescents in economically disadvantaged population

UC Riverside researchers discover way to halt cancer metastasis

Respiratory disease patients with arthritis struggle to use complex inhalers

Beetroot may reduce kidney failure risk after heart x-ray, research reveals

Pioneering study may pave way for effective painkillers to treat neuropathic pain

Researchers target abnormal epigenetic mechanisms involved in childhood cancers

Scientists explore connection between bad sleep habits and stiff blood vessels

New scanning technology could reduce number of biopsies on people with fatty liver disease

Cannabis use triggers schizophrenia and other psychiatric issues

Experimental molecular therapy restores insulation on peripheral nerves in mice

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

More work required to find the right drug dosage for pediatric patients

Multinational companies continue to manufacture unapproved formulations in India, research finds

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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