Pharmacology News and Research

Latest Pharmacology News and Research

New concise guide to pharmacology offers key information on major drug targets

The Concise Guide to PHARMACOLOGY 2017/18 is now available in the British Journal of Pharmacology. Published by Wiley on behalf of the British Pharmacological Society, the 440 page guide includes overviews of key properties for close to 1,700 human drug targets, identifies 3,500 ligands including more than 2,400 synthetic organic molecules and over 50 antibodies.

27 Oct 2017

Scientists get one step closer to reversing retinal degenerative diseases

Degenerative disorders affecting the retinal pigment epithelium (RPE), such as age-related macular degeneration and autosomal recessive bestrophinopathy, can ultimately lead to blindness. Some of these life-changing disorders are the result of mutations in a single gene, called BEST1.

25 Oct 2017

Resident physicians report lack of preparedness for counseling patients on medical cannabis

A recent study from Saint Peter's University Hospital in New Brunswick, New Jersey, highlights the need for further education among resident physicians in the use of medical cannabis.

23 Oct 2017

Researchers discover new regulatory role for protein that links diet and disease

A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation.

23 Oct 2017

Discovery of novel mechanism in the gut microbiome has implications for people with IBD

Many people associate the word "bacteria" with something dirty and disgusting. Dr. Pere Santamaria disagrees. Called the microbiome, the bacteria in our bodies have all kinds of positive effects on our health, Santamaria says. "The bacteria we have in our gut actually have many beneficial functions. They help in our digestion, prevent infection by pathogens and educate our immune system on what to fight."

23 Oct 2017

Researchers identify several previously unknown antibiotic resistance genes

Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have found several previously unknown genes that make bacteria resistant to last-resort antibiotics.

16 Oct 2017

Fundamental discovery may open potential for new types of cancer drugs

Many approved cancer therapies target a protein called epidermal growth factor receptor (EGFR) that regulates many crucial cellular processes and can speed the proliferation of tumor cells.

11 Oct 2017

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Hui Feng, MD, PhD, assistant professor of pharmacology and medicine at Boston University School of Medicine, is the recipient of a four-year, $792,000 grant from the American Cancer Society to study why T-cell acute lymphoblastic leukemia (T-ALL) is so aggressive and resistant to treatment.

10 Oct 2017

Cells lining blood vessels in the lungs exposed to bacterial toxins don’t die easy, UIC study says

Cells lining blood vessels in the lungs that are exposed to bacterial toxins don't die easy, according to a new study led by researchers at the University of Illinois at Chicago College of Medicine.

10 Oct 2017

Penn Medicine professor receives New Innovator Award from NIH

Hao Wu, PhD, an assistant professor of Genetics in the Perelman School of Medicine at the University of Pennsylvania has received a New Innovator Award from the National Institutes of Health. These awards provide each recipient $1.5 million over five years to pursue high-risk, high-reward investigations that could have implications for human health.

9 Oct 2017

UCLA scientists discover potential combination treatment for brain cancer in adults

UCLA scientists have discovered a potential combination treatment for glioblastoma, the deadliest form of brain cancer in adults. The three-year study led by Dr. David Nathanson, a member of UCLA's Jonsson Comprehensive Cancer Center, found that the drug combination tested in mice disrupts and exploits glucose intake, essentially cutting off the tumor's nutrients and energy supply.

9 Oct 2017

$Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus$

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

Proton pump inhibitors (PPIs)—medications commonly used to treat heartburn, acid reflux, and ulcers—have been linked with potentially serious side effects including a possible increased risk of bone fractures.

9 Oct 2017

New study reveals novel gene involved in maintaining body weight

A new study published online in The FASEB Journal reveals a novel gene involved in maintaining body weight. Specifically, the study suggests that GTRAP3-18 interacts with pro-opiomelanocortin (POMC) in the hypothalamus to regulate food intake and blood glucose levels.

4 Oct 2017

'First-in-man' clinical trial protocols often not guided by pharmacology, analysis shows

A new analysis published in the British Journal of Clinical Pharmacology indicates that 'first-in-man' clinical trial protocols in the Netherlands often lack a consistent consideration of pharmacokinetic and pharmacodynamic aspects in establishing drug doses.

4 Oct 2017

Statin use linked to reduced risk of S aureus bloodstream infection

Users of statins, widely prescribed for prevention of cardiac disease, have a 27% lower risk of contracting a Staphylococcus aureus (S aureus) bloodstream infection outside of a hospital, according to a new study in Mayo Clinic Proceedings.

3 Oct 2017

Researcher discovers why people tend to fall asleep when bored

University of Tsukuba researcher discovers why we have the tendency to fall asleep in the absence of motivating stimuli, i.e., when bored.

30 Sep 2017

UM SOM study finds intriguing relationship between sleep, cognition and kynurenine compound

More than 3.2 million Americans suffer from schizophrenia; about 100,000 people are newly diagnosed every year. The disease includes a wide range of symptoms including visual and auditory hallucinations, cognitive problems and motivational issues.

28 Sep 2017

Rogue messengers can negatively affect the body's immune system response against cancer

Researchers from Trinity College Dublin have made a discovery around treatment-resistant breast cancer that may turn the phrase, 'don't shoot the messenger', on its head. The scientists have found that cell to cell messengers released by cancer cells which are not responding to treatment, can negatively affect the body's immune system response against cancer.

28 Sep 2017

Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease

A study published in the journal Nature Neuroscience, from Nature publishing group, describes the identification of a novel molecular pathway that can constitute a therapeutic target for cognitive defects in Parkinson's disease.

25 Sep 2017

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an "organ-on-chip" model for two genetic forms of epilepsy. These disorders affect both brain and heart and improved modeling could lead to new drug treatments.

22 Sep 2017

Pharmacology News and Research

Latest Pharmacology News and Research

New concise guide to pharmacology offers key information on major drug targets

Scientists get one step closer to reversing retinal degenerative diseases

Resident physicians report lack of preparedness for counseling patients on medical cannabis

Researchers discover new regulatory role for protein that links diet and disease

Discovery of novel mechanism in the gut microbiome has implications for people with IBD

Researchers identify several previously unknown antibiotic resistance genes

Fundamental discovery may open potential for new types of cancer drugs

BU professor receives $792,000 grant to study about aggressiveness of T-ALL

Cells lining blood vessels in the lungs exposed to bacterial toxins don’t die easy, UIC study says

Penn Medicine professor receives New Innovator Award from NIH

UCLA scientists discover potential combination treatment for brain cancer in adults

Study finds no link between PPI use and bone fractures in patients with Barrett's esophagus

New study reveals novel gene involved in maintaining body weight

'First-in-man' clinical trial protocols often not guided by pharmacology, analysis shows

Statin use linked to reduced risk of S aureus bloodstream infection

Researcher discovers why people tend to fall asleep when bored

UM SOM study finds intriguing relationship between sleep, cognition and kynurenine compound

Rogue messengers can negatively affect the body's immune system response against cancer

Study identifies novel molecular interactions that explain cognitive defects in Parkinson's disease

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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