Pharmacology News and Research

Latest Pharmacology News and Research

Combination of two drugs could be effective strategy to target T-cell lymphocytic leukemia

Researchers have determined that two Phase 1 drugs (CX-4945 and JQ1) can work together to efficiently kill T-cell acute lymphoblastic leukemia cells while having minimal impact on normal blood cells.

24 Oct 2016

TxCell collaborates with UBC to develop CAR-Treg therapy to prevent graft rejection in organ transplantation

TxCell SA, a biotechnology company developing innovative, personalized cellular immunotherapies using regulatory T cells (Treg) to treat severe chronic inflammatory and autoimmune diseases, today announces the signature of a strategic R&D collaboration agreement with the University of British Columbia (UBC) in Vancouver, Canada, a leading global center for multidisciplinary research and teaching.

24 Oct 2016

UA neuroscientists receive $10.3 million grant to find cause for heightened risk of Alzheimer's in women

Why do more women than men get Alzheimer's disease? In their quest to find the answer, neuroscientist Roberta Diaz Brinton, PhD, and her collegues in the Center for Innovation in Brain Science at the University of Arizona Health Sciences, have been awarded a $10.3 million five-year Program Project Grant from the National Institute on Aging at the National Institutes of Health.

21 Oct 2016

Yale researchers identify chemical inhibitor that limits growth of lung tumor cells

A recently published Yale study may offer a new solution to fighting lung cancer.

20 Oct 2016

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase.

20 Oct 2016

Scientists use new technique to improve accuracy of detecting protein microcrystals

In a collaborative study, scientists from MIPT and JINR (Joint Institute for Nuclear Research) have increased the accuracy of detecting valuable protein crystals measuring just a few microns.

20 Oct 2016

Salk scientist receives NIH Pioneer Award to support innovative biomedical research

Salk Professor Juan Carlos Izpisua Belmonte has been awarded a 2016 National Institutes of Health Pioneer Award, a highly coveted grant that supports the most innovative biomedical research, for his work in stem cell biology and regeneration.

18 Oct 2016

Scientists identify novel strategy to treat pancreatic cancer

Researchers have found that a protein called SLC6A14 is overexpressed by several fold in pancreatic tumors taken from patients and in cancerous pancreatic cells lines compared with normal pancreatic tissue or normal pancreatic cells.

18 Oct 2016

Study quantifies burden of adverse drug reactions in general adult population

In a study of 1000 adult patients with unplanned admission to a tertiary hospital in Singapore, the prevalence of adverse drug reactions (ADRs) at the time of admission was 12.4 percent, and the prevalence of ADRs causing admission to the hospital was 8.1 percent.

17 Oct 2016

UT Southwestern researcher wins prestigious 2016 Transformative Research Award

Dr. Rama Ranganathan, Director of the Cecil H. and Ida Green Comprehensive Center for Molecular, Computational, and Systems Biology at UT Southwestern Medical Center, has been awarded a prestigious 2016 Transformative Research Award from the National Institutes of Health's Common Fund.

17 Oct 2016

New stem cell-based strategy may help predict heart-damaging effects of drugs

Coaxing stem cells from patients to become heart cells may help clinicians personalize drug treatments and prevent heart-related toxicity.

17 Oct 2016

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Giving mice a gene mutation linked to eating disorders in people causes feeding and behavior abnormalities similar to symptoms often seen in patients with eating disorders. Only female mice are affected by the gene mutation, and some of the abnormalities in the female mice depend on whether they are housed alone or together with other mice.

13 Oct 2016

High folate intake may increase risk of peripheral neuropathy in older adults with common gene variant

Consuming too much folate (vitamin B9) is associated with increased risk for a nerve-damage disorder in older adults who have a common genetic variant.

12 Oct 2016

Fetal brains use unique amplifier to transmit signals, research shows

Fetal brains use a special amplifier in order to transmit signals, according to research published in the journal eLife by George Washington University's (GW) Matthew Colonnese, Ph.D. and Yasunobu Murata, Ph.D. Early neural connections are sparse, weak, and unreliable.

12 Oct 2016

Females respond differently when isolated from social group, study finds

While male and female mice have similar responses to physical stress, research from the Hotchkiss Brain Institute at the University of Calgary, Canada, suggests females, not males, feel stressed when alone.

12 Oct 2016

New review questions safety of estrogen replacement therapy

Although individuals often consume natural products because of their potential health benefits, a new review indicates that it is not clear whether the benefits of plant-derived compounds that mimic estrogen outweigh the possible health risks.

11 Oct 2016

Study finds new therapeutic target to prevent progression of rare blood cancer

In a laboratory study, Upstate Medical University researcher Golam Mohi, Ph.D., his graduate student Yue Yang, and colleagues, have found that the loss of gene EZH2 promotes the development of Myelofibrosis (MF) in mice.

7 Oct 2016

BUSM researchers identify new therapeutic target for treating compulsive binge eating

A new therapeutic target for the treatment of compulsive binge eating has been identified by researchers at Boston University School of Medicine.

6 Oct 2016

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

As demand for the widely used blood thinning drug heparin continues to grow, experts worry of possible shortages of the essential medication.

6 Oct 2016

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects.

5 Oct 2016

Pharmacology News and Research

Latest Pharmacology News and Research

Combination of two drugs could be effective strategy to target T-cell lymphocytic leukemia

TxCell collaborates with UBC to develop CAR-Treg therapy to prevent graft rejection in organ transplantation

UA neuroscientists receive $10.3 million grant to find cause for heightened risk of Alzheimer's in women

Yale researchers identify chemical inhibitor that limits growth of lung tumor cells

New study raises serious safety concerns in clinical use of caspase inhibitors for liver injury

Scientists use new technique to improve accuracy of detecting protein microcrystals

Salk scientist receives NIH Pioneer Award to support innovative biomedical research

Scientists identify novel strategy to treat pancreatic cancer

Study quantifies burden of adverse drug reactions in general adult population

UT Southwestern researcher wins prestigious 2016 Transformative Research Award

New stem cell-based strategy may help predict heart-damaging effects of drugs

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

High folate intake may increase risk of peripheral neuropathy in older adults with common gene variant

Fetal brains use unique amplifier to transmit signals, research shows

Females respond differently when isolated from social group, study finds

New review questions safety of estrogen replacement therapy

Study finds new therapeutic target to prevent progression of rare blood cancer

BUSM researchers identify new therapeutic target for treating compulsive binge eating

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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