Pharmacology News and Research

Latest Pharmacology News and Research

Researchers study how epigenetic alterations contribute to age-related increases in breast cancer risk

Age is a key risk factor for breast cancer. A recent study by researchers from the Dartmouth-Hitchcock Norris Cotton Cancer Center, "Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation," examines the connection between cancer and the aging process to see if epigenetic DNA alterations might contribute to age-related increases in breast cancer risk.

31 Jan 2014

University of Liverpool receives funding to continue reducing impact of adverse reactions to medicinal drugs

The Medical Research Council (MRC) Centre for Drug Safety Science at the University of Liverpool has received three million pounds of new funding from MRC to allow it to continue reducing the impact of adverse reactions to medicinal drugs.

30 Jan 2014

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

Johns Hopkins researchers have discovered that valproic acid, a widely prescribed drug for treating epilepsy, has the additional benefits of reducing fat accumulation in the liver and lowering blood sugar levels in the blood of obese mice.

30 Jan 2014

Scientists develop monoclonal antibodies that may lead to new, innovative treatments for cancer patients

Using monoclonal antibodies to fight cancer is a complex, yet promising area of study. At Memorial Sloan Kettering Cancer Center, physician-scientists have focused their attention on expanding the current therapeutic antibody repertoire, and believe a newly developed platform will do just that - ultimately leading to new and innovative treatments for cancer patients with a broad range of malignancies.

29 Jan 2014

Low levels of pro-inflammatory cytokine in brain are important for cognition

Although inflammation is frequently a cause of disease in the body, research from The University of Texas Health Science Center at San Antonio indicates that low levels of a pro-inflammatory cytokine in the brain are important for cognition. Cytokines are proteins produced by the immune system.

28 Jan 2014

ITAC assists in international distribution of NanoLogix products by Nasaem Al-Jazira

NanoLogix Inc. (NNLX), an innovator in the rapid detection, identification and determination of antibiotic resistance and sensitivity of live bacteria, announces that the State of Ohio Department of Economic Development's International Trade Assistance Center (ITAC) based at Youngstown State University (YSU) is providing support to Hubbard Ohio-based NanoLogix Inc. for international distribution of NanoLogix products by Nasaem Al-Jazira, a Saudi Arabian Trading and Distribution Company.

27 Jan 2014

Bristol-Myers Squibb fourth quarter 2013 revenues increase 6% to $4.4 billion

Bristol-Myers Squibb Company today reported results for the fourth quarter and full year of 2013. The fourth quarter was highlighted by the company's announcement to sell its diabetes business as part of the continued evolution of its successful BioPharma strategy to a specialty care model. The company achieved important regulatory milestones in the quarter for Eliquis in the U.S., daclatasvir/asunaprevir in Japan, daclatasvir in Europe and Farxiga in the U.S. In addition, the company provided financial guidance for 2014.

24 Jan 2014

Scientists aim to develop business plan to guide drug development for potential use in patients

What if an experimental treatment for an aggressive breast cancer had the potential to save women's lives, but nobody could use it because there was no money to develop and test it? With funding sources for research and development more scarce than in the past, it is not an unusual situation. It's a problem that Sourav Sinha, a Master's degree candidate at Rutgers' Graduate School of Biomedical Sciences, is working to tackle head-on.

24 Jan 2014

e-Therapeutics temporarily stops phase I trials of ETS2101 due to drug supply issue

e-Therapeutics plc today announces that recruitment of patients into both of the ongoing phase I trials of ETS2101 has been halted temporarily because of a practical issue with stored drug for the trials.

24 Jan 2014

Extracts from birch tree helps damaged skin around wounds to regenerate more quickly

Extracts from the birch tree have served for centuries as a traditional means of helping the damaged skin around wounds to regenerate more quickly. Prof. Dr. Irmgard Merfort from the Institute of Pharmaceutical Sciences of the University of Freiburg and her team have now explained the molecular mechanism behind the wound-healing effect of an extract from the outer white layer of the tree's bark.

24 Jan 2014

Rival proteins’ relative expression levels in cancer cells could be biomarkers for prognosis, treatment

Consider two drivers, each with a key that fits the same car. Driver 1 wants simply to turn on the ignition and leave the vehicle idling, ready and waiting to roll. Driver 2 wants to take it on a destructive joy ride.

24 Jan 2014

AACN invites nurses, other healthcare professionals to 2014 National Teaching Institute & Critical Care Exposition

The American Association of Critical-Care Nurses (AACN) invites nurses and other healthcare professionals who care for high acuity and critically ill patients and their families to its 2014 National Teaching Institute & Critical Care Exposition (NTI) in Denver, May 19-22, with preconferences May 17-18.

23 Jan 2014

Scientists identify channel that acts as 'brake', limiting spontaneous pain

Scientists have identified a channel present in many pain detecting sensory neurons that acts as a 'brake', limiting spontaneous pain. It is hoped that the new research, published today [22 January] in the Journal of Neuroscience, will ultimately contribute to new pain relief treatments.

22 Jan 2014

Erosive GERD treatments: an interview with Professor Joaquim Moraes-Filho, University of São Paulo Medical School

Gastroesophageal Reflux Disease (GERD) is a condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications.

20 Jan 2014

Studies aim to address urgent need to identify possible new methods for mesothelioma treatment

Mesothelioma is a very aggressive cancer associated with asbestos exposure, which is usually diagnosed in an advanced stage. So far no therapeutic strategy has proven effective against this deadly cancer and the prognosis remains very poor with only few exceptions.

20 Jan 2014

Babies born to smoking mothers have 47% increase in odds of becoming overweight

Many women are encouraged to quit smoking when they become pregnant using nicotine replacement therapy (NRT) whether as gum, transdermal patches, nasal spray or lozenges.

16 Jan 2014

Research shows biological link between paternal diet and health of offspring

Research involving rats suggests that there is a biological link between paternal diet, bodyweight and health at the time of conception and the health of his offspring. In a new research report published online in The FASEB Journal, scientists show that if male rats ate a high fat diet, had diabetes and were obese, their offspring had altered gene expression in two important metabolic tissues--pancreas and fat (even though they were not yet obese).

16 Jan 2014

Study shows direct link between metabolism in brain cells and ability to signal information

A new study by scientists at McGill University and the University of Zurich shows a direct link between metabolism in brain cells and their ability to signal information. The research may explain why the seizures of many epilepsy patients can be controlled by a specially formulated diet.

16 Jan 2014

Too many medications associated with increased risk of admissions for patients with multiple conditions

Patients with a single illness who take many drugs have an increased risk of being admitted to hospital, but for patients with multiple conditions, taking many medicines is now associated with a near-normal risk of admission. This is the key finding of work published in the British Journal of Clinical Pharmacology.

16 Jan 2014

Research opens door to new direction of PAH treatment

The development of new, more effective vasodilators to treat pulmonary arterial hypertension has been hampered because of their systemic toxicity and adverse side effects. An international team of investigators seeking to surmount these problems and increase drug efficacy have determined that a vascular homing peptide can selectively target hypertensive pulmonary arteries to boost the pulmonary but not systemic effects of vasodilators. Importantly for potential clinical use, this peptide retains its activity when given sublingually. The results using a rat model of PAH are published in the American Journal of Pathology.

8 Jan 2014

Pharmacology News and Research

Latest Pharmacology News and Research

Researchers study how epigenetic alterations contribute to age-related increases in breast cancer risk

University of Liverpool receives funding to continue reducing impact of adverse reactions to medicinal drugs

Johns Hopkins researchers discover epilepsy drug reduces obesity-related blood sugar levels

Scientists develop monoclonal antibodies that may lead to new, innovative treatments for cancer patients

Low levels of pro-inflammatory cytokine in brain are important for cognition

ITAC assists in international distribution of NanoLogix products by Nasaem Al-Jazira

Bristol-Myers Squibb fourth quarter 2013 revenues increase 6% to $4.4 billion

Scientists aim to develop business plan to guide drug development for potential use in patients

e-Therapeutics temporarily stops phase I trials of ETS2101 due to drug supply issue

Extracts from birch tree helps damaged skin around wounds to regenerate more quickly

Rival proteins’ relative expression levels in cancer cells could be biomarkers for prognosis, treatment

AACN invites nurses, other healthcare professionals to 2014 National Teaching Institute & Critical Care Exposition

Scientists identify channel that acts as 'brake', limiting spontaneous pain

Erosive GERD treatments: an interview with Professor Joaquim Moraes-Filho, University of São Paulo Medical School

Studies aim to address urgent need to identify possible new methods for mesothelioma treatment

Babies born to smoking mothers have 47% increase in odds of becoming overweight

Research shows biological link between paternal diet and health of offspring

Study shows direct link between metabolism in brain cells and ability to signal information

Too many medications associated with increased risk of admissions for patients with multiple conditions

Research opens door to new direction of PAH treatment

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in