Pharmacology News and Research

Latest Pharmacology News and Research

New way to effectively make designer drugs that hit collections of protein targets simultaneously

An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively make designer drugs that hit multiple protein targets at once.

13 Dec 2012

Targeted micro-bubbles could help detect heart disease

Heart disease is a leading cause of death throughout the world. Doctors say that it is important to detect heart disease early before it becomes too serious. Now, researchers at the University of Missouri have found a way that they believe could help detect heart disease before it progresses too far as well as identify patients who are at risk for strokes.

13 Dec 2012

CRI, SU2C form Cancer Immunology Translational Research Dream Team

Stand Up To Cancer (SU2C) and the Cancer Research Institute (CRI) announce the formation of a Dream Team project dedicated to cancer immunology - "Immunologic Checkpoint Blockade and Adoptive Cell Transfer in Cancer Therapy."

13 Dec 2012

Drugs that bind to specific serotonin receptors can improve and impair female sexual function

Drugs that bind to specific serotonin receptors in the brain can both improve and impair female sexual function in non-human primates.

12 Dec 2012

Industry sponsored clinical trials present a more favourable picture of reported findings

Studies reporting the results of industry sponsored clinical trials present a more favourable picture of the effects of drugs and medical devices than those reporting on non-industry sponsored trials, according to a new Cochrane systematic review. The researchers call for a rethink of the way that industry bias is handled in medical guidelines and reviews.

12 Dec 2012

Activated astrocytes could play a harmful role in Alzheimer's disease

A research team composed of University of Kentucky researchers has published a paper which provides the first direct evidence that activated astrocytes could play a harmful role in Alzheimer's disease.

12 Dec 2012

FAC PET identifies liposarcoma tumors that are sensitive to chemotherapy

Liposarcoma, the most common type of sarcoma, is an often lethal form of cancer that develops in fat cells. It is particularly deadly, in part, because the tumors are not consistently visible with positron emission tomography (PET) scans that use a common probe called FDG and because they frequently do not respond to chemotherapy.

11 Dec 2012

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a role in cell signaling that is crucial to new drug development.

11 Dec 2012

New study could help develop anti-inflammatory drugs with fewer side effects

10 Dec 2012

Perceptive Informatics launches Customer Care office in Shanghai to serve biopharmaceutical researchers

Perceptive Informatics, a leading eClinical solutions provider and a subsidiary of PAREXEL International Corporation (NASDAQ: PRXL), today announced that it has opened a Customer Care office in Shanghai to service biopharmaceutical researchers in China and Taiwan who are using Perceptive's technology solutions.

From Parexel 10 Dec 2012

Brazil Scientific Motility Society awards training grant to GHSU’s Department of Physiology

The Department of Physiology at the Medical College of Georgia at Georgia Health Sciences University has been awarded a training grant from the Brazil Scientific Motility Society to advance the education of future scientists and scientific discovery.

10 Dec 2012

BDNF molecule appears to play a direct role in regulation of blood pressure

Researchers at Oregon Health & Science University's School of Dentistry have made an important connection between a molecule critical to nerve cells and high blood pressure. Production of the molecule Brain-Derived Neurotrophic Factor (BDNF) appears to increase dramatically in blood pressure-sensing nerve cells during hypertension.

7 Dec 2012

Bilirubin can inhibit clogging of arteries and prevent deadly consequences

Each year, about 610,000 Americans suffer their first heart attack, according to the Centers for Disease Control and Prevention. Heart attacks and other symptoms of cardiovascular disease can be caused when blockage occurs in the arteries. In a new study from the University of Missouri, a scientist has discovered a natural defense against arterial blockage: bilirubin.

6 Dec 2012

New technology allows noninvasive SpHb assessments for children undergoing brain surgery

For children undergoing brain surgery, a new technology allows noninvasive, continuous monitoring of blood hemoglobin levels, according to a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

6 Dec 2012

Bisphenol A blocks calcium channels in cell membranes

Bisphenol A, a substance found in many synthetic products, is considered to be harmful, particularly, for fetuses and babies. Researchers from the University of Bonn have now shown in experiments on cells from human and mouse tissue that this environmental chemical blocks calcium channels in cell membranes. Similar effects are elicited by drugs used to treat high blood pressure and cardiac arrhythmia. The results are now presented in the journal "Molecular Pharmacology."

6 Dec 2012

No serious complications of regional nerve blocks in children

A review of more than 15,000 nerve block procedures performed in children at U.S. hospitals finds little or no risk of permanent complications or death, reports a study in the December issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

6 Dec 2012

Study questions value of coated, low-dose aspirin therapy

Roughly one-fifth of Americans take low-dose aspirin every day for heart-healthy benefits. But, based on either urine or blood tests of how aspirin blocks the stickiness of platelets - blood cells that clump together in the first stages of forming harmful clots - up to one third of patients are deemed unlikely to benefit from daily use. Such patients are called "aspirin resistant." Clots are the main cause of most heart attacks and strokes.

6 Dec 2012

Pharmacology News and Research

Latest Pharmacology News and Research

New way to effectively make designer drugs that hit collections of protein targets simultaneously

Targeted micro-bubbles could help detect heart disease

CRI, SU2C form Cancer Immunology Translational Research Dream Team

Drugs that bind to specific serotonin receptors can improve and impair female sexual function

Industry sponsored clinical trials present a more favourable picture of reported findings

Activated astrocytes could play a harmful role in Alzheimer's disease

FAC PET identifies liposarcoma tumors that are sensitive to chemotherapy

Alpha arrestins may play a role in cell signaling that is crucial to new drug development

New study could help develop anti-inflammatory drugs with fewer side effects

Perceptive Informatics launches Customer Care office in Shanghai to serve biopharmaceutical researchers

Brazil Scientific Motility Society awards training grant to GHSU’s Department of Physiology

BDNF molecule appears to play a direct role in regulation of blood pressure

Bilirubin can inhibit clogging of arteries and prevent deadly consequences

New technology allows noninvasive SpHb assessments for children undergoing brain surgery

Bisphenol A blocks calcium channels in cell membranes

No serious complications of regional nerve blocks in children

Study questions value of coated, low-dose aspirin therapy

USPTO approves patent for Axiogenesis’ in vitro drug discovery assay to treat HCM

Flexion raises $20M in Series B financing round

Researchers discover first-ever mouse model of diffuse idiopathic skeletal hyperostosis

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Pharmacology News and Research

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