Pharmacology News and Research

Latest Pharmacology News and Research

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

In a new study in mice, a scientific collaboration centered at Brown University lays out in unprecedented detail a neurological signaling breakdown in Angelman syndrome, a disorder that affects thousands of children each year, characterized by developmental delay, seizures, and other problems.

14 Feb 2013

Preemptive treatment effective for hyperemesis gravidarum and severe morning sickness

`In a study to be presented on February 14 between 1:15 p.m., and 3:30 p.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting -, in San Francisco, California, researchers will present data showing the effectiveness of preemptive treatment for hyperemesis gravidarum and severe morning sickness.

13 Feb 2013

GSK, Vanderbilt partner to develop and commercialize new therapies for severe obesity

Vanderbilt University announced today that it has signed a collaboration agreement with GlaxoSmithKline (GSK) for the discovery, development and commercialization of novel therapies for severe obesity.

13 Feb 2013

Valproate, pregnancy and IQ: an interview with Professor Kimford Meador

Valproate (sodium salt of valproic acid) is an anticonvulsant used in the treatment of epilepsy, migraine and bipolar disorder as well as some other off label psychiatric indications.

11 Feb 2013

NIH researchers review research on dog cranium development

Man's best friend may touch our hearts with their empathy, companionship, playfulness and loyalty, and they may also lead us to a deeper understanding of our heads.

11 Feb 2013

Scientists demonstrate new approach for quickly assembling drug-like compounds

A team of scientists anchored at Yale University has demonstrated a new, highly versatile approach for quickly assembling drug-like compounds, establishing a broad new route to drug discovery and medical treatment.

11 Feb 2013

Innovative drug discovery in Europe supported by Bayer

Bayer HealthCare initiated and will coordinate a newly founded pan-European consortium, named European Lead Factory, which has been launched to enhance early drug discovery addressing the need for innovative drugs. The new five-year project will create an exceptional small molecule library collection allowing drug discovery on innovative and promising targets from pharma companies and academia.

7 Feb 2013

Patients undergoing major vascular surgery procedures are at increased risk of stroke

Patients undergoing major vascular surgery procedures are at increased risk of stroke, leading to a high mortality rate and prolonged hospitalization, according to a study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

6 Feb 2013

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

A previously poorly investigated signalling pathway is crucial for the growth and proliferation of prostate cancer cells. An international research team discovered this when studying the enzyme "soluble adenylyl cyclase" that produces the second messenger molecule cAMP.

5 Feb 2013

Regular exercise reduces development of painful diabetic neuropathy in animals

Regular exercise reduces the development of painful diabetic neuropathy in animals—apparently related to increased expression of a protective substance called "heat shock protein" 72 (Hsp72), reports an experimental study in the February issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

5 Feb 2013

UPCI researchers uncover new technique to stop growth of cancer cells

University of Pittsburgh Cancer Institute (UPCI) researchers have uncovered a technique to halt the growth of cancer cells, a discovery that led them to a potential new anti-cancer therapy.

5 Feb 2013

PET with 11C-PIB can positively visualize amyloid deposits in the heart

While amyloid imaging may now be most associated with detecting plaques in the brain, it has the potential to change the way cardiac amyloidosis is diagnosed. According to first-of-its-kind research published in the February issue of The Journal of Nuclear Medicine, positron emission tomography (PET) with 11C-PIB can positively visualize amyloid deposits in the heart.

5 Feb 2013

GVK Biosciences extends GOBIOM license to Biomarker Qualification Group of US FDA

GVK Biosciences (GVK BIO) today announced that it is extending its Clinical Biomarker Database (GOBIOM) license to the Biomarker Qualification Group of the US Food and Drug Administration (US FDA).

5 Feb 2013

Epidermal growth factor speeds recovery of blood-making stem cells after radiation exposure

Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.

3 Feb 2013

Galectin submits GR-MD-02 IND application with FDA for treatment of liver fibrosis

Galectin Therapeutics, the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, announced today that it submitted an Investigational New Drug (IND) application to the US Food and Drug Administration (FDA) on January 30, 2013.

1 Feb 2013

Gene variant boosts ulcer susceptibility in NSAID users

A single nucleotide polymorphism in the cytochrome P450 2C gene cluster influences the risk for peptic ulcer disease in people taking non-steroidal anti-inflammatory drugs, a study reveals.

31 Jan 2013

OncoEthix initiates OTX015 Phase I study in hematologic malignancies

OncoEthix, the Swiss-based specialist in oncology drug development, announces progress in its Phase I study of OTX015, a novel BET bromodomain inhibitor, with the first dosing of a patient.

31 Jan 2013

UCSD molecular biologist to receive Charles Rodolphe Brupbacher Prize for Cancer Research

Molecular biologist Michael Karin is to receive this year's Charles Rodolphe Brupbacher Prize for Cancer Research in recognition of his studies on the role of chronic inflammation in the development of tumors. The award, which carries CHF 100,000 in prize money, is considered one of the highest accolades for cancer researchers worldwide. The awards ceremony takes place in Zurich this Thursday in the framework of an international symposium on "Breakthroughs in Cancer Research and Therapy".

30 Jan 2013

Insight into reasons why precocious puberty occurs in females

New research from Oregon Health & Science University has provided significant insight into the reasons why early-onset puberty occurs in females.

30 Jan 2013

AACN 2013 National Teaching Institute & Critical Care Exposition to be held in Boston

The American Association of Critical-Care Nurses (AACN) invites nurses and other healthcare professionals who care for high acuity and critically ill patients and their families to its 2013 National Teaching Institute & Critical Care Exposition (NTI) in Boston May 20-23, with preconferences May 18-19.

29 Jan 2013

Pharmacology News and Research

Latest Pharmacology News and Research

Study demonstrates how CN2097 works to restore neural functions impaired by Angelman syndrome

Preemptive treatment effective for hyperemesis gravidarum and severe morning sickness

GSK, Vanderbilt partner to develop and commercialize new therapies for severe obesity

Valproate, pregnancy and IQ: an interview with Professor Kimford Meador

NIH researchers review research on dog cranium development

Scientists demonstrate new approach for quickly assembling drug-like compounds

Innovative drug discovery in Europe supported by Bayer

Patients undergoing major vascular surgery procedures are at increased risk of stroke

Previously poorly investigated signalling pathway crucial for proliferation of prostate cancer cells

Regular exercise reduces development of painful diabetic neuropathy in animals

UPCI researchers uncover new technique to stop growth of cancer cells

PET with 11C-PIB can positively visualize amyloid deposits in the heart

GVK Biosciences extends GOBIOM license to Biomarker Qualification Group of US FDA

Epidermal growth factor speeds recovery of blood-making stem cells after radiation exposure

Galectin submits GR-MD-02 IND application with FDA for treatment of liver fibrosis

Gene variant boosts ulcer susceptibility in NSAID users

OncoEthix initiates OTX015 Phase I study in hematologic malignancies

UCSD molecular biologist to receive Charles Rodolphe Brupbacher Prize for Cancer Research

Insight into reasons why precocious puberty occurs in females

AACN 2013 National Teaching Institute & Critical Care Exposition to be held in Boston

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Pharmacology News and Research

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How can microdialysis benefit drug development

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