Pharmacology News and Research

Latest Pharmacology News and Research

Restless legs syndrome linked to hypertension

Up to 15 percent of the population has restless legs syndrome. Restless legs syndrome is characterized by crawling sensations and repeated muscle twichings in one or both legs, and an uncontrollable urge to move them - which may compel a person to walk in circles for hours at night.

12 Oct 2011

Furiex announces publications and presentations about antibacterial drug JNJ-Q2

Furiex Pharmaceuticals, Inc. today announced recent and upcoming publications and presentations about the novel investigational antibacterial drug JNJ-Q2.

12 Oct 2011

Scientists discover two HIV variants in cerebrospinal fluid of HAD patients

When the virus that causes AIDS infects the central nervous system, it can lead to the development of a severe neurological disease called HIV- associated dementia.

7 Oct 2011

Tips on how to prevent unnecessary medication/supplement mishaps

Navigating the supplement and medication maze can get confusing especially when you have multiple prescriptions. It is important to organize yourself with your medications and supplements to prevent unnecessary mishaps.

7 Oct 2011

AMRI announces final results from ALB-127158(a) Phase I clinical studies on obesity

AMRI announced today the final results from its Phase I clinical studies on its novel MCH1 receptor antagonist, ALB-127158(a) during the 29th Annual Scientific Meeting of the Obesity Society in Orlando, Fla.

4 Oct 2011

Public health officials should determine community storage of anthrax-preventing antibiotics

As part of preparations for a possible large-scale anthrax attack, public health officials on the state and local levels should determine where and how anthrax-preventing antibiotics should be stored in their communities, says a new report from the Institute of Medicine.

1 Oct 2011

UCSF protein researcher wins NIH's Early Independence Award

James Fraser, PhD, a protein researcher who studies structural biology at the California Institute for Quantitative Biosciences (QB3) at the University of California, San Francisco (UCSF), is one of 10 recipients of a prestigious award for young scientists given for the first time by the National Institutes of Health.

1 Oct 2011

Circadian subsidiary submits IND application to FDA to initiate VGX-100 study against cancer

Circadian Technologies Limited is extremely proud to announce that its 100% owned subsidiary, Vegenics Pty Ltd, has submitted an investigational new drug application to the U.S. Food and Drug Administration to initiate clinical studies of VGX-100.

1 Oct 2011

Fat-rich 'western diet' fuels cardiovascular disease, type 2 diabetes and obesity

A major risk factor for cardiovascular disease, type 2 diabetes and other health- and life-threatening conditions, obesity is epidemic in the United States and other developed nations where it's fueled in large part by excessive consumption of a fat-rich "Western diet."

30 Sep 2011

UNC professor wins 2011 PECASE award for research into alcohol addiction

During a White House ceremony next month, Thomas L. Kash, PhD, assistant professor in the department of pharmacology and the UNC Bowles Center for Alcohol Studies at the University of North Carolina at Chapel Hill School of Medicine will receive the Presidential Early Career Award for Scientists and Engineers.

30 Sep 2011

Immune cells in brain linked with behavioural responses to alcohol

University of Adelaide researchers have found that immune cells in your brain may contribute to how you respond to alcohol.

30 Sep 2011

Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

A pathway activated in cancer plays an unexpected key role in metabolic diseases like type 2 diabetes, according to a study by researchers at Children's Hospital Boston. Evidence that the Lin28/let-7 pathway influences the cellular response to glucose provides a unifying theme to perplexing data that associates human genetic variation with diabetes risk.

30 Sep 2011

Circadian files IND with FDA for VGX-100 for the treatment of cancer patients with solid tumors

Circadian Technologies Limited (ASX: CIR, OTCQX:CKDXY) is extremely proud to announce that its 100% owned subsidiary, Vegenics Pty Ltd, has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) to initiate clinical studies of VGX-100. The first trial (Phase I) will involve the treatment of a variety of different cancer types in patients with late stage cancer.

29 Sep 2011

Immune cells in brain may predict alcohol abuse effects

Adelaide University researchers say there's a growing body of evidence that alcohol triggers rapid changes in the immune system in the brain and this is behind responses like staggering and slurring. They claim that blocking part of the immune system might reduce alcohol abuse and help prevent drink driving accidents.

29 Sep 2011

Stroke risk increases with even small rises in blood pressure

Small rises of blood pressure may greatly increase a person's risk of stroke, according to new research. The study review, published in the journal Neurology, analyzed the results of 12 studies on blood pressure and stroke incidences among a total of 518,520 adults.

29 Sep 2011

Three papers reveal structure and workings of G protein-coupled receptors

Three international teams of scientists, led by researchers at the University of California San Diego, University of Michigan and Stanford University, have published a trio of papers describing in unprecedented detail the structure and workings of G protein-coupled receptors (GPCRs), a large family of human proteins that are the target of one-third to one-half of modern drugs.

29 Sep 2011

Low plasma level of copper and zinc in pregnant women may be associated with spontaneous abortion

Scientists at the University of Granada have confirmed that a low plasma level of copper and zinc in pregnant women may be a factor associated with spontaneous abortion, a hypothesis that had not been confirmed to date, and which had never been proven in humans before.

28 Sep 2011

Researchers validate two parasite enzymes as potential anti-malarial drug targets

Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source.

28 Sep 2011

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of how this process works could have important implications for numerous diseases, including cancer and Parkinson's disease.

28 Sep 2011

Weill Cornell receives NIH's T-R01 Award for spina bifida research

The National Institutes of Health (NIH) has awarded a five-year, $5.5 million Transformative Research Project (T-R01) Award to fund research into risk factors for spina bifida and related congenital defects in which an area of the affected baby's spine or brain is not fully enclosed.

27 Sep 2011