Pharmacology News and Research

Latest Pharmacology News and Research

Harmful effects of tobacco smoke on atherosclerosis are greater in women than in men

The harmful effects of tobacco smoke on atherosclerosis, one of the driving forces of cardiovascular disease, are greater in women than in men.

29 Aug 2011

Elsevier, Pharmaron sign multi-year contract for Reaxys

Elsevier, a world-leading provider of scientific, technical and medical information products and services, announced today that Pharmaron, a premier drug R&D service provider for the pharmaceutical and biotech industry, has signed a multi-year contract with Elsevier, which will provide unlimited Reaxys access to all Pharmaron researchers.

29 Aug 2011

EAS/ESC develops new dyslipidaemias guidelines

Clinicians should aim for comprehensive lipid control using lifestyle as a first step and tailoring treatment to patients. Lifestyle interventions, including stopping smoking, improving diet, exercising sufficiently and moderate alcohol consumption, should be the crucial first step for managing lipids in all patients.

29 Aug 2011

Plants stop lethal bleedings after birth in Tanzanian women

Researchers at the Faculty of Pharmaceutical Sciences, University of Copenhagen, have examined a number of plants which are used for illegal abortions in Tanzania. The lab tests show that several of the plants can make the uterus tissue contract and that the plants therefore can be used to stop lethal bleedings after birth. This new knowledge is now to be conveyed in rural Tanzania where access to medicine often is difficult.

26 Aug 2011

GCC hormone receptor may also help fight obesity

The hormone receptor guanylyl cyclase C (GCC) has been established as a suppressor of colorectal cancer tumors, but new evidence from Thomas Jefferson University suggests it may also help fight one of the country's biggest pandemics: obesity.

26 Aug 2011

Tropical plants may contain basis of new and effective treatments for ovarian cancer

Tropical plants may contain the basis of new and effective treatments for ovarian cancer, according to researchers at the Universities of Strathclyde and Portsmouth.

25 Aug 2011

New Pressurized Olfactory Device shows direct CNS effect of morphine

A simple new approach to nasal drug administration may allow morphine and other strong pain medications to be targeted directly to the central nervous system (CNS), reports an experimental study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Aug 2011

Simvastatin may reduce spinal cord damage from ischemia/reperfusion injury

The cholesterol-lowering drug simvastatin appears to reduce spinal cord injury caused by oxygen deprivation in experimental animals, according to a study in the September issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

24 Aug 2011

Spinifex secures AU$6.25 million in expanded Series B funding

Spinifex Pharmaceuticals, an Australian pain drug development company, today announced it has secured a further AU$6.25 million of venture capital investment from GBS Venture Partners Limited, Brandon Capital Partners Pty Limited, Uniseed Management Pty Limited and UniQuest Pty Limited to fund the development of its pain management drug, EMA401.

23 Aug 2011

Activus to receive NEDO grant for 'Development of Innovative Ophthalmic Solutions'

Sosei Group Corporation, announces that its wholly owned subsidiary Activus Pharma Co., Ltd. is to receive a grant for its "Development of Innovative Ophthalmic Solutions" from the New Energy and Industrial Technology Development Organization (NEDO), an Incorporated Administrative Agency under the Ministry of Economy, Trade and Industry (METI) as a part of their FY2011 Innovation Promotion Programme.

22 Aug 2011

Tiny molecule could bind to B cell EB12 receptor and prevent cancer

Infection with Epstein Barr means that the B cells, which are the primary memory cells of the immune system, are hi-jacked. When the virus has penetrated, researchers observe an excess of a special bio-antenna, a receptor known as EB12, suddenly sprouting from the surface of the B cells. But why they do so remains a mystery.

22 Aug 2011

Scientists shed light on the dark secret of Queen Hatshepsut's deadly medication

The corpus delicti is a plain flacon from among the possessions of Pharaoh Hatshepsut, who lived around 1450 B.C., which is on exhibit in the permanent collection of the Egyptian Museum of the University of Bonn. For three and a half millennia, the vessel may have held a deadly secret. This is what the Head of the collection, Michael H-veler-M-ller and Dr. Helmut Wiedenfeld from the university's Pharmacology Institute just discovered.

20 Aug 2011

Conference to discuss latest research on gender disparities in cardiovascular disease

Heart disease has sometimes been considered a men's health issue, but the statistics prove otherwise. In the US alone, more than 42 million women live with the problem. Heart disease is responsible for more than one-third of deaths among American women each year, making it the number one killer of females older than 20.

19 Aug 2011

PAREXEL recognized as Company of the Year for the Pharmaceutical Industry

PAREXEL International Corporation, a leading global biopharmaceutical services provider, has been named Company of the Year for the Pharmaceutical Industry in The Eighth Annual International Business Awards, the only global, all-encompassing business awards program honoring great performances in business.

From Parexel 17 Aug 2011

Researchers identify mesothelin antibody that could detect early-stage ovarian cancer

Using a new approach to developing biomarkers for the very early detection of ovarian cancer, researchers at Rush University Medical Center have identified a molecule in the bloodstream of infertile women that could one day be used to screen for those at high risk for the disease — or even those with early-stage ovarian cancer.

17 Aug 2011

Moderate social drinking reduces risk of dementia and cognitive impairment

Moderate social drinking significantly reduces the risk of dementia and cognitive impairment, according to an analysis of 143 studies by Loyola University Chicago Stritch School of Medicine researchers.

17 Aug 2011

Study investigates autism spectrum disorder, sibling recurrence

The risk that an infant with an older sibling with autism also will develop the disorder, previously estimated at between 3 and 10 percent, is substantially higher at approximately 19 percent, a large, international, multi-site study led by researchers at the UC Davis MIND Institute has found.

16 Aug 2011

Gene therapy cocktail can treat inherited diseases with 'misfolded' proteins

In a kind of molecular gymnastics, scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with "misfolded" proteins.

16 Aug 2011

Mice with enzyme deficiency are unable to properly assess threat

Do you run when you should stay? Are you afraid of all the wrong things? An enzyme deficiency might be to blame, reveals new research in mice by scientists at the University of Southern California.

12 Aug 2011

Research team reports first genetic sequencing of urothelial carcinoma

In an article published online this week in Nature Genetics, a University of Colorado Cancer Center team in partnership with universities in China and Denmark reports the first genetic sequencing of urothelial (transitional) carcinoma, the most prevalent type of bladder cancer.

12 Aug 2011