Pharmacology News and Research

Latest Pharmacology News and Research

RainDance, 454 Life Sciences collaborate to launch core ADME gene screening research panel

RainDance Technologies, Inc., and 454 Life Sciences, a Roche Company, today announced a collaboration for the development and commercialization of a targeted next-generation sequencing (NGS) solution for the simple and cost-effective investigation of drug absorption, distribution, metabolism, and excretion (ADME).

9 Mar 2011

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

Merck, known as MSD outside of the United States and Canada, announced that several new data analyses from Phase III studies of VICTRELIS, its investigational oral hepatitis C protease inhibitor, will be presented at The International Liver CongressTM / 46th European Association for the Study of the Liver annual meeting.

9 Mar 2011

Parkinson's disease medication turns on critical gene, protects brain cells

In a major breakthrough in the battle against Parkinson's disease, researchers at the University of Colorado School of Medicine have discovered a drug that stops the progression of the degenerative illness in mice and is now being tested in humans.

9 Mar 2011

UCLA, Fibrocell Science enter scientific collaboration to advance cell therapy

Fibrocell Science, Inc., a biotechnology company focused on the development of autologous cell therapies for aesthetic, medical and scientific applications, announced today that it has entered into a scientific collaboration with University of California, Los Angeles to research the conversion of dermal fibroblasts into pure functional human cell types that may have greater regenerative capacity.

9 Mar 2011

Scientists develop innovative device to efficiently identify CTCs in blood

Circulating tumor cells, which play a crucial role in cancer metastasis, have been known to science for more than 100 years, and researchers have long endeavored to track and capture them.

8 Mar 2011

Ambry, RainDance enter new collaboration to develop and commercialize ADME screening

RainDance Technologies, Inc. and Ambry Genetics, today announced a new collaboration focused on the development and commercialization of a comprehensive drug absorption, distribution, metabolism, and excretion genetic screening panel for use on next-generation sequencing systems.

8 Mar 2011

NanoLogix announces MRSA testing preliminary results, new Science Advisory Board members at UTHSC

NanoLogix, a biotechnology innovator in the rapid detection and identification of live-cell microorganisms, announces preliminary results of MRSA testing at the University of Texas Health Science Center - Houston. Dr. Jonathan Faro, M.D., Ph.D. has found NanoLogix technology is able to deliver results for MRSA in 6 hours, as opposed to conventional culture-based testing wait times of 24 to 48 hours.

7 Mar 2011

FDA accepts Lundbeck's clobazam NDA for review

Lundbeck Inc. today announced the U.S. Food and Drug Administration has accepted for review a New Drug Application for the investigational compound clobazam as adjunctive therapy in treating seizures associated with Lennox-Gastaut syndrome in patients two years and older.

5 Mar 2011

Journal of Chronic Obstructive Pulmonary Disease becomes official journal of COPD Foundation

COPD: Journal of Chronic Obstructive Pulmonary Disease, the first journal dedicated to publishing a range of research on the impact of COPD, has become the official journal of the COPD Foundation.

5 Mar 2011

Triptolide isolated from Chinese medicinal plant blocks gene control machinery in cells

Researchers at the Johns Hopkins School of Medicine have discovered that a natural product isolated from a traditional Chinese medicinal plant commonly known as thunder god vine, or lei gong teng, and used for hundreds of years to treat many conditions including rheumatoid arthritis works by blocking gene control machinery in the cell. The report, published as a cover story of the March issue of Nature Chemical Biology, suggests that the natural product could be a starting point for developing new anticancer drugs.

4 Mar 2011

Celerion completes Clean Room, pharmacist certification to comply with USP 797 guidelines

Celerion, the premier provider of innovative early stage drug development solutions, announces the completion of a Clean Room and pharmacist certification to comply with USP 797 guidelines.

3 Mar 2011

Tobacco smoking leads to less activity in the 'executive center' of brain

Tobacco smoking is the leading preventable cause of death and disease in the U.S., with more than 400,000 deaths each year attributable to smoking or its consequences. And yet teens still smoke. Indeed, smoking usually begins in the teen years, and approximately 80 percent of adult smokers became hooked by the time they were 18. Meanwhile, teens who don't take up smoking usually never do.

3 Mar 2011

Scientists discover signaling pathway in brain to induce cellular leptin resistance

Researchers at UT Southwestern Medical Center have identified a signaling pathway in the brain that's sufficient to induce cellular leptin resistance, a problem that decreases the body's ability to "hear" that it is full and should stop eating.

2 Mar 2011

Research: Tanning bed exposure can lead to serious skin problems

Tanning bed exposure can produce more than some tanners may bargain for, especially when they self-diagnose and use the radiation to treat skin eruptions, according to research conducted by the Indiana University School of Medicine Department of Dermatology.

2 Mar 2011

NCI sponsors multi-center phase 2 study of entinostat-anastrozole combination in triple negative breast cancer

Syndax Pharmaceuticals, a clinical-stage epigenetics oncology company, announced the National Cancer Institute (NCI) will sponsor a multi-center phase 2 study of Syndax's lead product entinostat, a novel inhibitor of histone deacetylases (HDAC), and anastrozole, an aromatase inhibitor, in postmenopausal women with operable triple negative breast cancer to evaluate biomarkers and surrogates for response.

2 Mar 2011

Bioanalysis accepted for coverage by EMBASE & Scopus

EMBASE is a premier online resource for biomedical literature, with over 24 million indexed records and more than 7,500 current, mostly peer-reviewed journals, EMBASE quickly and accurately delivers biomedical answers. Scopus is the largest abstract and citation database of research literature and quality web sources covering nearly 18,000 titles from more than 5,000 publishers.

1 Mar 2011

Anesthesia & Analgesia journal receives notification from LÄK for lack of IRB approval in 89 articles

The peer-reviewed medical journal Anesthesia & Analgesia received notification from Landesärztekammer Rheinland-Pfalz, the Rheinland State Medical Board, that there was no IRB approval for 89 articles published Dr. Joachim Boldt, including 22 published by A&A from 1999-2009.

1 Mar 2011

Tenofovir gel more effective than oral tablet for HIV treatment: Study

In the first study to make head-to-head comparisons between tenofovir gel and oral tenofovir - two promising approaches for preventing HIV in women - researchers found that daily use of the vaginal gel achieved a more than 100-times higher concentration of active drug in vaginal tissue than did the oral tablet, while, compared to the gel, the tablet used daily was associated with a 20-times higher active drug concentration in blood.

1 Mar 2011

Anti-AIDS gel shows promise

Dr. Ian McGowan, a professor of medicine at the University of Pittsburgh who is leading a second-phase study of the gel said, “These are early results, but [they] help set the stage for current and future trials of rectal microbicides and the development of a rectal-specific formulation of tenofovir gel.” Researchers have focused on the use of microbicides such as tenofovir, as a preventive treatment to be used in vaginal sex. However, scientists think unprotected anal sex is much more risky.

1 Mar 2011

Medical experts propose six-point framework for safe production and use of Kava plant

Medical and scientific experts propose a global framework for the safe production and use of the medicinal plant Kava, including further clinical testing In Australia.

1 Mar 2011

Pharmacology News and Research

Latest Pharmacology News and Research

RainDance, 454 Life Sciences collaborate to launch core ADME gene screening research panel

Merck to present VICTRELIS phase III study data against HCV at EASL annual meeting

Parkinson's disease medication turns on critical gene, protects brain cells

UCLA, Fibrocell Science enter scientific collaboration to advance cell therapy

Scientists develop innovative device to efficiently identify CTCs in blood

Ambry, RainDance enter new collaboration to develop and commercialize ADME screening

NanoLogix announces MRSA testing preliminary results, new Science Advisory Board members at UTHSC

FDA accepts Lundbeck's clobazam NDA for review

Journal of Chronic Obstructive Pulmonary Disease becomes official journal of COPD Foundation

Triptolide isolated from Chinese medicinal plant blocks gene control machinery in cells

Celerion completes Clean Room, pharmacist certification to comply with USP 797 guidelines

Tobacco smoking leads to less activity in the 'executive center' of brain

Scientists discover signaling pathway in brain to induce cellular leptin resistance

Research: Tanning bed exposure can lead to serious skin problems

NCI sponsors multi-center phase 2 study of entinostat-anastrozole combination in triple negative breast cancer

Bioanalysis accepted for coverage by EMBASE & Scopus

Anesthesia & Analgesia journal receives notification from LÄK for lack of IRB approval in 89 articles

Tenofovir gel more effective than oral tablet for HIV treatment: Study

Anti-AIDS gel shows promise

Medical experts propose six-point framework for safe production and use of Kava plant

Industry Focus - Biopharma eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus - Biopharma eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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