Pharmacology News and Research

Latest Pharmacology News and Research

Animal research shows potential of amphetamine-like drug for treating cocaine addiction

New research in monkeys suggests the feasibility of treating cocaine addiction with a "replacement" drug that mimics the effects of cocaine but has less potential for abuse - similar to the way nicotine and heroin addictions are treated.

7 Apr 2008

Rare genetic syndrome may hold key to cure for heat stroke

A genetic disorder that can cause a fatal rise in body temperature in some patients undergoing general anesthesia may hold the key to a cure for heat stroke, according to research published in the April 4 edition of the journal Cell.

4 Apr 2008

New web portal, the PSI Structural Genomics Knowledgebase to advance protein studies

The Protein Structure Initiative (PSI), an effort supported by the National Institutes of Health (NIH), has launched an online resource that will enable scientists from across biomedical disciplines to easily access a wealth of information about proteins and to speed discovery about these molecules.

4 Apr 2008

PET confirmed as valuable cancer diagnostic and disease-staging tool

The recent release of data by the National Oncologic PET Registry (NOPR) showing that positron emission tomography (PET) produced scans revealing disease at a molecular level, which then caused physicians to change treatment plans for more than one-third of participating patients, has corroborated decades of nuclear medicine research.

28 Mar 2008

Beta-blockers heal the heart via the brain when administered during heart failure

Up to now, it was thought that beta-blockers work directly on the heart, but the new study shows that the drugs may also act via the brain, suggesting that future therapies to treat cardiovascular disease could be targeting the central nervous system.

26 Mar 2008

Researchers develop method to rapidly ID optimal drug cocktails

UCLA researchers have developed a feedback control scheme that can search for the most effective drug combinations to treat a variety of conditions, including cancers and infections.

18 Mar 2008

Discovery of new rare type of haemoglobin

Scientists at the University of Bonn have discovered a new rare type of haemo-globin. Haemoglobin transports oxygen in the red blood corpuscles.

18 Mar 2008

Prescribing costs increase dramatically when people reach 65

Prescribing costs increase dramatically when people reach 65, according to a detailed analysis of more than five million patients published in the March issue of the British Journal of Clinical Pharmacology.

14 Mar 2008

Pain receptor in brain may be linked to learning and memory

Scientists have long known that the nervous system receptor known as TRPV1 can affect sensations of pain in the body.

14 Mar 2008

Aspirin/NSAID interaction in treatment for second stroke

Stroke patients who use ibuprofen for arthritis pain or other conditions while taking aspirin to reduce the risk of a second stroke undermine aspirin's ability to act as an anti-platelet agent, researchers at the University at Buffalo have shown.

13 Mar 2008

The potential for cannabinoids as medicines

Smokers trying to quit in the future could do it with the help of cannabis based medicines, according to research from The University of Nottingham.

10 Mar 2008

Integrin beta3 protein yields clues to autism

Many children with autism have elevated blood levels of serotonin - a chemical with strong links to mood and anxiety.

6 Mar 2008

Arsenic aids tumor imaging when joined to cancer-homing drug

Arsenic linked to a drug that binds to the blood vessels of cancerous tumors provides a powerful imaging agent that could one day allow physicians to detect hard-to-find tumors and more closely monitor cancer's response to therapy, researchers at UT Southwestern Medical Center have found.

6 Mar 2008

Experimental cancer drug MI-219 promising in preclinical studies

Researchers have long searched for a novel cancer drug that activates a certain protein to kill tumor cells.

4 Mar 2008

Cell proteins could offer a future drug target against weight gain

Two cell proteins that relax the gut and help accommodate a big meal have been identified by UCL (University College London) scientists.

4 Mar 2008

Ten years down the line a pill to cure obesity

British scientists say they may have found a new way to treat obesity by stopping the stomach from expanding.

4 Mar 2008

Arsenic used to label antibodies for the detection of tumors

3 Mar 2008

Hydroxyurea for sickle cell patients

An independent panel convened this week by the NIH concluded that the use of hydroxyurea for sickle cell patients should be increased in adolescents and adults.

28 Feb 2008

Cancer-related protein Akt may play key role in Alzheimer's disease

The cancer-related protein Akt may profoundly influence the fate of the tau protein, which forms bundles of tangled nerve cell fibers in the brain associated with Alzheimer's disease, reports a new study led by researchers at the University of South Florida and the Mayo Clinic in Jacksonville, FL.

28 Feb 2008

Springer launches 18,000 searchable online protocols in life sciences and biomedicine

Springer Science+Business Media (www.springer.com) has announced the release of Springer Protocols, a protocol database of more than 18,000 searchable online protocols in life sciences and biomedicine.

28 Feb 2008