Pharmacology News and Research

Latest Pharmacology News and Research

BRAF gene mutations predict sensitivity to a new class of drug

A team of researchers led by scientists at Memorial Sloan-Kettering Cancer Center have discovered that a new class of drugs -- now in early stage clinical trials -- work best in patients with mutations in the BRAF gene.

7 Nov 2005

First steps taken to treat human hereditary blindness

A team led by Krzysztof Palczewski, Ph.D., chair of pharmacology at the Case Western Reserve University School of Medicine, has taken the first steps in treating an eye disease causing irreversible congenital blindness in millions of people worldwide by successfully testing two new treatments in mice.

3 Nov 2005

Environment is a major factor influencing the success of the addiction recovery

New research in monkeys suggests that, although living in an "enriched" environment can make someone less vulnerable to abusing cocaine, once started, extended drug abuse can eliminate the social advantage the abuser originally had.

30 Oct 2005

Natural blood sugar level lowering compound could lead to new drugs to treat type 2 diabetes

A carbohydrate isolated from the liver lowers blood sugar levels after it is injected into diabetic rats, according to research carried out by a team of experts at the University of Virginia Health System (UVHS).

27 Oct 2005

Survival benefits of longer-term tamoxifen use may take years to appear

The survival benefits of longer-term therapy using tamoxifen may take at least nine years to develop, according to a new study published in the December 1, 2005 issue of Cancer, a peer-reviewed journal of the American Cancer Society.

24 Oct 2005

Mixed carbon nanotubes and standard urban particulates suggests a risk of thrombosis from airborne pollution

Carbon nanoparticles - both those unleashed in the air by engine exhaust and the engineered structures thought to have great potential in medical applications - promote blood-clotting, scientists report in an upcoming edition of the British Journal of Pharmacology.

23 Oct 2005

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

A molecule that has long been an obstacle to cancer chemotherapy and drug treatments for brain disorders may soon become an ally in the fight against Alzheimer's disease, according to researchers at Washington University School of Medicine in St. Louis and the University of Rochester.

20 Oct 2005

New hormone discovery has implications for liver diseases

Researchers at UT Southwestern Medical Center have discovered that the small intestine communicates with the liver to control the production of bile acids - a finding that has great medical implications in treating people at risk for certain types of liver disease.

11 Oct 2005

Discovery provides an understanding of the mechanisms of oocyte death and a way to identify potential clinical treatments for infertility

An immature egg's internal nutrient supply is critical to its survival, an insight that offers a new route to understanding and treating infertility due to egg death, according to Duke University Medical Center researchers.

9 Oct 2005

New light shed on the causes of drug addiction

A methamphetamine epidemic rages across the United States with addicts blinded by uncontrollable desires for a drug that eventually thrusts them into a dire and catastrophic existence. Doctors don't have any effective treatments for these addicts, or for any other drug addicts; drug addiction is a disease that remains a medical mystery.

4 Oct 2005

Plant-derived compounds appear to block the activity of an enzyme that triggers inflammation in joints

The findings came to light while the researchers were studying the wildly different ways in which cells in human blood vessels and joints respond to pressure gradients generated from liquid moving along their surface, a force called shear stress.

3 Oct 2005

Survival of heart attack patients placed on beta-blocker therapy corresponds to specific variations in their genes

Survival of heart attack and unstable angina patients placed on beta-blocker therapy corresponds to specific variations in their genes, according to a study by researchers at Washington University School of Medicine in St. Louis and the Mid America Heart Institute in Kansas City.

27 Sep 2005

Possibility of tailored treatments for addiction based on how a person's genes behave

Scientists have learned how a genetic variation long suspected in making some people susceptible to alcoholism and narcotic drug addiction actually does so.

27 Sep 2005

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Their findings, which may point to new approaches to developing improved treatment options for the disease, are published in the journal Nature.

26 Sep 2005

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Exposure to lead in early childhood and adolescence may contribute to hypertension-related decline that can impair a person's cognitive abilities, according to a new study presented at the 2005 American Heart Association's High Blood Pressure Research meeting.

26 Sep 2005

Set of simple "rules" that nature appears to use to design proteins

By examining how proteins have evolved, UT Southwestern Medical Center researchers have discovered a set of simple "rules" that nature appears to use to design proteins, rules the scientists have now employed to create artificial proteins that look and function just like their natural counterparts.

26 Sep 2005

Parkinson's dark period can be minimized or alleviated with the right kind of care

Some people call it "the dark time," the period between when a person is diagnosed with Parkinson's disease and when treatment with medication begins.

26 Sep 2005

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Chronically high levels of insulin, as is found in many people with obesity and Type II diabetes, may block specific hormones that trigger energy release into the body, according to researchers at the University of California, San Diego (UCSD) School of Medicine.

22 Sep 2005

Presence of environmental chemicals in human milk does not necessarily indicate health risks for infants

"We strongly emphasize that the mere presence of an environmental chemical in human milk does not indicate that a health risk exists for breast-fed infants," said Cheston M. Berlin, Jr., M.D., Penn State University professor of pediatrics and pharmacology.

22 Sep 2005

Strokes and heart attacks can be prevented in people with high blood pressure

Most strokes and heart attacks in people with high blood pressure can be abolished by simply combining effective, modern blood pressure lowering drugs with treatment to reduce cholesterol.

6 Sep 2005

Pharmacology News and Research

Latest Pharmacology News and Research

BRAF gene mutations predict sensitivity to a new class of drug

First steps taken to treat human hereditary blindness

Environment is a major factor influencing the success of the addiction recovery

Natural blood sugar level lowering compound could lead to new drugs to treat type 2 diabetes

Survival benefits of longer-term tamoxifen use may take years to appear

Mixed carbon nanotubes and standard urban particulates suggests a risk of thrombosis from airborne pollution

Molecule P-glycoprotein (Pgp), may help reduce risk of Alzheimer's

New hormone discovery has implications for liver diseases

Discovery provides an understanding of the mechanisms of oocyte death and a way to identify potential clinical treatments for infertility

New light shed on the causes of drug addiction

Plant-derived compounds appear to block the activity of an enzyme that triggers inflammation in joints

Survival of heart attack patients placed on beta-blocker therapy corresponds to specific variations in their genes

Possibility of tailored treatments for addiction based on how a person's genes behave

Chronically high levels of insulin may block specific hormones that trigger energy release into the body

Lead exposures early in life combined with high blood pressure in working age adults may lead to diminishing cognitive abilities in later life

Set of simple "rules" that nature appears to use to design proteins

Parkinson's dark period can be minimized or alleviated with the right kind of care

Study clarifies insulin's role in blocking release of energy in patients with type II diabetes

Presence of environmental chemicals in human milk does not necessarily indicate health risks for infants

Strokes and heart attacks can be prevented in people with high blood pressure

Industry Focus - Biopharma eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus - Biopharma eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in