Pharmacology News and Research

Latest Pharmacology News and Research

Vitamin discovery offers clues for cancer chemotherapy

NH-Dartmouth Medical School cancer researchers, in a fusion of biochemistry and genetics, have discovered a new vitamin in a molecular pathway central to such vital processes as gene regulation, metabolism and aging. And, they found that milk contains this nutrient.

15 May 2004

Ritalin drug used to treat hyperactive children boosts the potency of Parkinson's drug levodopa

A well-known drug used to treat hyperactive children boosts the potency of another drug that reduces Parkinson's disease symptoms, an Oregon Health & Science University study has found.

6 May 2004

Pregnancy massage may reduce the risk of premature births

Pregnancy massage long has been known to help expectant mothers feel better, and a new study shows it may well provide an even more important benefit – reducing the risk of premature births.

5 May 2004

New technique to deliver gene therapy to soft-tissue tumors

Using new research and technology that shows bone marrow-derived mesenchymal stem cells (MSCs) will engraft at the site of a tumor and contribute to the growth of stromal fibroblasts (the healthy tissue surrounding a tumor)

2 May 2004

Smoking tobacco with a water pipe increasingly popular among women

Smoking tobacco using a water pipe - also called a hookah -- generally is viewed in a more positive light than smoking cigarettes, particularly for women, according to one of the first studies on water pipe and cigarette smoking to look at social attitudes and gender.

26 Apr 2004

Cardiac Intensive Care Unit lowest heart attack rates in the state of Texas

That’s because the CICU he runs has the lowest myocardial infarction (heart attack) mortality in the entire South Texas region. It has one of the lowest rates in the state of Texas.

23 Apr 2004

Dietary supplement may improve immune function in the elderly

A recent clinical study has demonstrated that 7-oxo Dehydroepiandrosterone taken orally twice daily by healthy adults over a period of one month augments several key T-cell mediated immune function parameters compared to placebo administration.

20 Apr 2004

Jefferson scientists learn how HIV causes dementia

Ever since the AIDS epidemic began more than two decades ago, scientists have been trying to understand why as many as one-quarter of those infected with HIV develop dementia.

19 Apr 2004

FDA announces science-based approach to protecting Americans from unsafe dietary supplements

Speaking before the American Society for Pharmacology and Experimental Therapeutics (ASPET) and the American Society for Nutritional Sciences, Dr. Lester M. Crawford, Acting Commissioner of the Food and Drug Administration (FDA), today outlined the agency's science-based approach to protecting American consumers from unsafe dietary supplements.

19 Apr 2004

Curry offers possible protection against Alzheimer’s disease

A new study has found that curry, a common and popular cooking additive, could be an effective enhancer of an enzyme that protects the brain against oxidative conditions.

19 Apr 2004

Genetic connection between humans, mice and dogs

The discovery that humans are genetically close to mice and dogs might make people develop greater respect for life, J. Craig Venter, a major contributor to the historic mapping of the human genome, said.

16 Apr 2004

Decongestant may increase blood pressure

A common ingredient in over-the-counter decongestants -- pseudoephedrine -- may increase blood pressure and the risk of life-threatening or disabling strokes in susceptible patients, researchers at Vanderbilt University Medical Center have reported.

15 Apr 2004

Protein identification gets a speed boost

But the labor intensity of the procedure is now a thing of the past for researchers in the Oregon Health & Science University School of Medicine. The Proteomics Shared Resource, an unassuming but state-of-the-art lab on the fifth floor of OHSU's Medical Research Building, can process more than three times as many protein samples in half a day, and much of it can be done by one person.

14 Apr 2004

Researchers examine community-based drinkers rather than abstinent alcoholics

Almost all knowledge about brain damage due to chronic alcohol consumption has been gathered from alcoholics, who have generally been studied toward the end of their institutionalized treatment program (several weeks after their last drink) or many months into abstinence.

13 Apr 2004

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Continuing studies about an important regulatory protein kinase complex called I-kappa-B kinase (or IKK) have now shown that a subunit of IKK – IKK alpha – influences the outer layer of skin in developing mice to control the eventual shape of the full-grown skeleton and skull.

7 Apr 2004

DakoCytomation has acquired exclusive worldwide rights to develop and commercialize pharmacogenomic diagnostic tests in the field of oncology

Human Genome Sciences, Inc. announced today a license agreement with DakoCytomation A/S (Glostrup, Denmark), under which DakoCytomation has acquired exclusive worldwide rights to develop and commercialize pharmacogenomic diagnostic tests in the field of oncology based on the TRAIL Receptor-1 (TRAIL-R1) and TRAIL Receptor-2 (TRAIL-R2) proteins.

31 Mar 2004

Trial of new drug that may halt progression of Type I Diabetes

The results of a long-term clinical trial on a new drug designed to inhibit the progression of type I diabetes was announced at the International Diabetes Society meeting in Cambridge, England, March 29. The findings of the 18-month long clinical trial confirm the drug's efficacy in improving a diabetic's ability to produce insulin.

30 Mar 2004

New Australian collaboration to discover new drugs targeting epilepsy and anxiety

Bionomics Limited and Southern Cross University announced today that they had established a collaboration to discover new drugs targeting epilepsy and anxiety. Under the arrangement, Southern Cross University will provide Bionomics with extracts from its collection of Australian-based natural products, together with expertise in natural products chemistry.

30 Mar 2004

Halting the development of certain pancreatic, ovarian, colon and lung cancers may be possible with new therapy

By investigating a single molecule that influences cell growth, a research group in the Purdue Cancer Center, including Brian S. Henriksen, has gained new insight into the chain of events that make some cancer cells divide uncontrollably, insight that may eventually lead to a way to break that chain, stopping cancer in its tracks. The molecule, known as Icmt, has a critical role in the development of Ras, an ordinarily beneficial protein that tells a cell to divide. The research group has determined how to inhibit Icmt's influence on Ras, without which the protein cannot develop effectively into an instigator of cell growth.

28 Mar 2004

St. John’s wort may interfere with cancer-fighting drug’s ability to prevent relapse in leukemia patients

St. John’s wort, an herb thought to be a safe, natural remedy for mild depression, may interfere with a powerful cancer-fighting drug’s ability to prevent relapse in leukemia patients, a University of Florida pharmacy researcher will report March 27 at the annual meeting of the American Society for Clinical Pharmacology and Therapeutics.

26 Mar 2004