Pharmacology News and Research

Latest Pharmacology News and Research

Novel machine learning algorithm helps find drug binding sites

Scientists from the iMolecule group at Skoltech Center for Computational and Data-Intensive Science and Engineering developed BiteNet, a machine learning algorithm that helps find drug binding sites, i.e. potential drug targets, in proteins.

27 Oct 2020

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

The Alzheimer's Biomarkers Consortium - Down Syndrome, a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health, to expand research on the biomarkers of Alzheimer's disease in adults with Down syndrome.

22 Oct 2020

Study identifies potential target for treating polyploidal giant cancer cells

As researchers and medical professionals work to develop new treatments for cancer, they face a variety of challenges.

21 Oct 2020

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain could guide design of antiviral agents

The outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 virus continues to cause human infection and mortality worldwide. Currently, there are no specific viral protein-targeted therapeutics available.

20 Oct 2020

Researchers develop a molecular docking based webserver to predict drug targets

A highly effective drug therapy is urgently required to combat coronavirus disease 2019 (COVID-19). The authors of this article have developed a molecular docking based webserver, namely D3Targets-2019-nCoV, with two functions, one is for predicting drug targets for drugs or active compounds observed from clinic or in vitro/in vivo studies, the other is for identifying lead compounds against potential drug targets via docking.

20 Oct 2020

Study helps restore retinal and visual functions of mice models of inherited retinal disease

A breakthrough study, led by researchers from the University of California, Irvine, results in the restoration of retinal and visual functions of mice models suffering from inherited retinal disease.

20 Oct 2020

OMA announces availability of updated Pediatric Obesity Algorithm

The Obesity Medicine Association today announced the immediate availability of the 2020-2022 Pediatric Obesity Algorithm, which includes new information for clinicians such as specific considerations for special populations, nutritional recommendations for patients with obesity and adiposity-related diseases, and advanced therapies for pediatric obesity.

19 Oct 2020

Synthetic signals could help control tissue regeneration, guide cellular therapies

For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways.

16 Oct 2020

UCI-led researchers receive $3 million NIH grant for 4D Nucleome project

The National Institutes of Health has awarded a team of researchers, led by the University of California, Irvine's Xiangmin Xu, PhD, a five-year, $3 million grant for a project titled, "Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus."

15 Oct 2020

Study may lead to new therapies to improve survival in septic patients

Each year, some 270,000 Americans die from sepsis, in which the release of normally helpful infection-fighting chemicals in the body triggers an unusually extreme immune response - powerful enough to cause life-threatening damage to blood vessels and organs.

15 Oct 2020

G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Dr. Guangyu Wu is dissecting the molecular homing that enables a nascent protein to ultimately find its way to the surface of a cell as a mature receptor type that helps us taste, smell and even regulate our mood and immunity.

14 Oct 2020

Scientists produce biodegradable nanocoating with antimicrobial and anti-reflective properties

Scientists from Russia and Switzerland have probed into nanostructures covering the corneas of the eyes of small fruit flies. Investigating them the team learned how to produce the safe biodegradable nanocoating with antimicrobial, anti-reflective, and self-cleaning properties in a cost-effective and eco-friendly way.

14 Oct 2020

Two well-known neurochemicals found to be involved in sub-second perception, cognition

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals -; dopamine and serotonin -; are at work at sub-second speeds to shape how people perceive the world and take action based on their perception.

12 Oct 2020

Dopamine and serotonin play role in perception and decision-making

Scientists at Wake Forest School of Medicine have recorded real time changes in dopamine and serotonin levels in the human brain that are involved with perception and decision-making.

12 Oct 2020

Penn receives $4.5 million NIH grant to create a comprehensive resource for women’s health

Junhyong Kim, PhD, Chair and Patricia M. Williams Professor of Biology in the School of Arts and Sciences, and Kate O'Neill, MD MTR, Assistant Professor, Department of Obstetrics and Gynecology in the Perelman School of Medicine, have been awarded a Human BioMolecular Atlas Program (HuBMAP) grant supported by the Eunice Kennedy Shriver National Institute of Child Health & Human Development and the Common Fund of the National Institutes of Health.

9 Oct 2020

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

With a nearly $2.6 million grant from the National Institutes of Health, Michigan State University researchers are using nanoscopic particles to turn the body's own cells into weapons that cancer won't see coming.

9 Oct 2020

Researcher receives NIH award to explore effect of women's hormones on postpartum opioid relapse

When most people think of opioid addiction, they typically do not think of pregnant women. Unfortunately, however, the prevalence of opioid addiction during pregnancy has increased nearly 500% during the past 15 years.

8 Oct 2020

Simple sugar in human breast milk can promote myelin repair in multiple sclerosis patients

N-acetylglucosamine, a simple sugar found in human breast milk and sold as an over-the-counter dietary supplement in the United States, promotes myelin repair in mouse models and correlates with myelination levels in multiple sclerosis patients according to a new University of California, Irvine-led study.

8 Oct 2020

Researchers quantify aerosols generated during anesthetic procedures

Since the outset of the COVID-19 pandemic, there has been much debate about the danger to hospital staff from anaesthetic procedures. Concerns include that placing a tube in the patient's airway (intubation) before surgery or removing it at the end (extubation) may produce a fine mist of small particles (called aerosols) and spread the COVID-19 virus to nearby staff.

7 Oct 2020

Sofosbuvir combined with other antivirals is more effective against COVID-19, shows study

Columbia Engineering researchers report that Sofosbuvir-terminated RNA is more resistant to the proofreader of SARS-CoV-2, the virus that causes COVID-19, than Remdesivir-terminated RNA.

7 Oct 2020

Pharmacology News and Research

Latest Pharmacology News and Research

Novel machine learning algorithm helps find drug binding sites

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

Study identifies potential target for treating polyploidal giant cancer cells

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain could guide design of antiviral agents

Researchers develop a molecular docking based webserver to predict drug targets

Study helps restore retinal and visual functions of mice models of inherited retinal disease

OMA announces availability of updated Pediatric Obesity Algorithm

Synthetic signals could help control tissue regeneration, guide cellular therapies

UCI-led researchers receive $3 million NIH grant for 4D Nucleome project

Study may lead to new therapies to improve survival in septic patients

G protein-coupled receptors help humans taste, smell, and regulate mood and immunity

Scientists produce biodegradable nanocoating with antimicrobial and anti-reflective properties

Two well-known neurochemicals found to be involved in sub-second perception, cognition

Dopamine and serotonin play role in perception and decision-making

Penn receives $4.5 million NIH grant to create a comprehensive resource for women’s health

Developing a precision 'Trojan Horse' nanotherapy to treat breast cancer

Researcher receives NIH award to explore effect of women's hormones on postpartum opioid relapse

Simple sugar in human breast milk can promote myelin repair in multiple sclerosis patients

Researchers quantify aerosols generated during anesthetic procedures

Sofosbuvir combined with other antivirals is more effective against COVID-19, shows study

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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