Pharmacology News and Research

Latest Pharmacology News and Research

Direct oral anticoagulant does not appear to offer protection against severe COVID-19

DOAC (direct oral anticoagulant) pills are used in the treatment of atrial fibrillation by preventing blood clots. Even though blood clots are thought to contribute to complications from the new coronavirus infection, users of this class of drug do not seem to be protected against severe COVID-19, reports a large Swedish registry study from Karolinska Institutet published in The Journal of Internal Medicine.

1 Dec 2020

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

"But it's a marathon whereas you keep going, the trail gets rockier and then you lose your shoes," the 27-year-old said. "It gets harder as you get older. Things start to fail and all you can think about is how much worse it's going to get down the road."

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

Steam inhalation therapy found to inactivate SARS-CoV-2 virions

Researchers have published a study on the efficacy of steam inhalations as another possible treatment to help mitigate SARS-CoV-2 infection.

30 Nov 2020

Combining cell engineering with machine learning to design living medicines for cancer

Finding medicines that can kill cancer cells while leaving normal tissue unscathed is a Holy Grail of oncology research.

26 Nov 2020

Long-range regulation of tumor suppressor genes plays key role in cancer

Enhancers are regulatory elements that play an important role in cancer.Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, identified a novel enhancer.

25 Nov 2020

Antimicrobial found in soaps worsens fatty liver disease in mice

University of California San Diego School of Medicine researchers found evidence that triclosan -- an antimicrobial found in many soaps and other household items -- worsens fatty liver disease in mice fed a high-fat diet.

23 Nov 2020

Molecular action of tarantula toxin may hold clues to better control of chronic pain

Oversized, hairy tarantulas may be unsightly and venomous, but surprisingly their hunter toxin may hold answers to better control of chronic pain.

23 Nov 2020

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

Using computational methods, a team of researchers identified three compounds in traditional Chinese medicine that could be used against SARS-CoV-2.

23 Nov 2020

International trialists receive prestigious award for research on low-dose aspirin

The international trialists Professors Lars Wallentin, Jan van Gijn, Bo Norrving and Tom Meade were recognized for their work on low-dose aspirin, with the presentation of the International Aspirin Foundation Senior Science Award.

22 Nov 2020

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

Scientific analysis of a protein enzyme found in COVID-19 could lead to the development of new drugs to treat the virus, research led by Oxford Brookes University scientists has found.

20 Nov 2020

New druggable target for heart failure in neonates and infants identified

Researchers have identified a new druggable target for heart failure in neonates and infants, a condition for which there has been no specific treatment.

19 Nov 2020

Machine learning-based prediction model may enable early diagnosis of opioid use disorder

Researchers have used machine learning, a type of artificial intelligence, to develop a prediction model for the early diagnosis of opioid use disorder.

18 Nov 2020

Cannabidiol oils are equally or less effective at inhibiting certain cancer cell lines

Cannabidiol (CBD) oils are equally or less effective at inhibiting the growth of certain cancer cells compared to pure CBD, according to Penn State College of Medicine researchers.

18 Nov 2020

UCLA researchers pinpoint how smoking causes more severe COVID-19 infection

UCLA researchers using a model of airway tissue created from human stem cells have pinpointed how smoking cigarettes causes more severe infection by SARS-CoV-2, the virus that causes COVID-19, in the airways of the lungs.

17 Nov 2020

Natural products and herbal medicines show promise in fight against COVID-19

Researchers in China and the United States have called for more research into the potential prophylactic effects of natural products and herbal medicines on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and subsequent coronavirus disease 2019 (COVID-19).

17 Nov 2020

Study identifies new factor that offers potential strategy for treating obesity

Obesity is a serious global health problem and a risk factor for diseases such as type II diabetes, heart disease and fatty liver disease.

17 Nov 2020

Hydrogen therapy may help severely ill COVID-19 patients

Researchers from the Department of Critical Care Medicine, Sichuan Provincial People's Hospital, Chengdu in China, have explored the possibility of using hydrogen therapy on severely ill COVID-19 patients. The team published their study's findings, titled "Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients," in the latest issue of the journal Frontiers in Pharmacology.

17 Nov 2020

Baricitinib drug can reduce mortality in patients with moderate to severe COVID-19

The rheumatoid arthritis drug baricitinib can block viral entry and reduce mortality in patients with moderate to severe COVID-19, according to translational research by an international team coordinated by researchers from Karolinska Institutet in Sweden.

16 Nov 2020

Study reveals a previously undetected repertoire of cancer driver genes

A new study, led by researchers from the University of California, Irvine, has deepened the understanding of epigenetic mechanisms in tumorigenesis and revealed a previously undetected repertoire of cancer driver genes.

12 Nov 2020

Pharmacology News and Research

Latest Pharmacology News and Research

Direct oral anticoagulant does not appear to offer protection against severe COVID-19

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

Researchers successfully edit SIV virus from genomes of non-human primates

Steam inhalation therapy found to inactivate SARS-CoV-2 virions

Combining cell engineering with machine learning to design living medicines for cancer

Long-range regulation of tumor suppressor genes plays key role in cancer

Antimicrobial found in soaps worsens fatty liver disease in mice

Molecular action of tarantula toxin may hold clues to better control of chronic pain

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

International trialists receive prestigious award for research on low-dose aspirin

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

New druggable target for heart failure in neonates and infants identified

Machine learning-based prediction model may enable early diagnosis of opioid use disorder

Cannabidiol oils are equally or less effective at inhibiting certain cancer cell lines

UCLA researchers pinpoint how smoking causes more severe COVID-19 infection

Natural products and herbal medicines show promise in fight against COVID-19

Study identifies new factor that offers potential strategy for treating obesity

Hydrogen therapy may help severely ill COVID-19 patients

Baricitinib drug can reduce mortality in patients with moderate to severe COVID-19

Study reveals a previously undetected repertoire of cancer driver genes

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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