Pharmacology News and Research

Latest Pharmacology News and Research

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERT promoter -- the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma -- confers "immortality" on tumor cells, enabling the unchecked cell division that powers their aggressive growth.

10 Sep 2018

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption.

10 Sep 2018

Immune system that fights infection could join battle against opioid addiction

The same immune system that fights infection and the flu could join the battle against opioid addiction, new research out of the Vanderbilt Center for Addiction Research indicates.

7 Sep 2018

Study identifies intrinsic cell properties that influence fate of neural stem cells

Researchers from the University of California, Irvine have identified intrinsic cell properties that influence the fate of neural stem cells, affecting what type of brain cell they will form: neurons, astrocytes, or oligodendrocytes.

7 Sep 2018

Research team identifies new therapeutic target for castration-resistant prostate cancer

A collaborative research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target for one of the deadliest forms of cancer among men.

7 Sep 2018

Global warming may increase likelihood of HFMD transmission

Hand, foot, and mouth disease is a common childhood viral infection that is most common in warmer summer months.

6 Sep 2018

Study examines unnecessary medicine use in patients with advanced lung cancer

Individuals with advanced lung cancer often have other comorbid conditions, and many may be on complex, costly, and even inappropriate medication regimens.

6 Sep 2018

Bee venom may be effective treatment for eczema

Bee venom and its major component, melittin, may be effective treatments for atopic dermatitis (or eczema), according to a British Journal of Pharmacology study.

6 Sep 2018

Immune system may join battle against opioid addiction

The same immune system that fights infection and the flu could join the battle against opioid addiction, new research out of the Vanderbilt Center for Addiction Research indicates.

6 Sep 2018

New method may speed up development of novel drugs

Researchers of the University of Würzburg have developed a method that makes it possible to measure the activation of receptors in a very short time. This might speed up the development of new drugs.

6 Sep 2018

Huntington's disease may take effect much earlier in life than previously believed, study suggests

A new study published in the Proceedings of the National Academy of Sciences suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling the disease.

5 Sep 2018

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

New work from researchers at Columbia University Vagelos College of Physicians and Surgeons sheds light on how dopamine receptors signal within cells, opening the door for more targeted--and more tolerable--therapeutics to treat an array of neuropsychiatric disorders.

4 Sep 2018

Dr. Clinton Webb selected for top award from AHA Council on Hypertension

Dr. R. Clinton Webb, Herbert S. Kupperman Chair in Cardiovascular Disease in the Department of Physiology at the Medical College of Georgia at Augusta University, has been selected for the top award from the American Heart Association's Council on Hypertension.

4 Sep 2018

UCLA biologists find 8,000 new antibiotic combinations to be effective

Scientists have traditionally believed that combining more than two drugs to fight harmful bacteria would yield diminishing returns.

3 Sep 2018

Genetic mutations may drive tumor formation by blurring growth signals

Genetic mutations in a form of non-small cell lung cancer (NSCLC) may drive tumor formation by blurring cells' perception of key growth signals, according to a new laboratory study published August 31, 2018 in Science.

3 Sep 2018

Groundbreaking CURATE.AI platform halts progression of advanced cancer

A translational research team led by the National University of Singapore has harnessed CURATE.AI, a powerful artificial intelligence platform, to successfully treat a patient with advanced cancer, completely halting disease progression.

31 Aug 2018

NUS researchers harness AI platform to treat patient with advanced cancer

31 Aug 2018

Leukogene receives STTR grant to optimize compound for treatment-resistant multiple myeloma

A $2 million phase 2 Small Business Technology Transfer grant to optimize a promising new compound that has shown efficacy in preclinical studies against treatment-resistant multiple myeloma has been awarded to a Medical University of South Carolina startup company, Leukogene Therapeutics, Inc., in collaboration with MUSC researcher and company founder, Nathan G. Dolloff, Ph.D. Dolloff is an assistant professor in the Department of Cell and Molecular Pharmacology & Experimental Therapeutics at MUSC and a member of MUSC Hollings Cancer Center.

31 Aug 2018

Researchers take major step forward in finding safe and non-addictive pain killer

With the support of the National Institute on Drug Abuse, scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer to help fight the current opioid crisis in this country.

30 Aug 2018

Peptilogics held pre-IND meeting with FDA to develop PLG0206 for treating prosthetic joint infections

Peptilogics, a development stage company utilizing its innovative peptide platform to treat multidrug-resistant bacterial infections, today announced it recently held a pre-Investigational New Drug (pre-IND) meeting with the U.S. Food and Drug Administration to discuss the regulatory pathway for the development of PLG0206 for the treatment of prosthetic joint infections.

25 Aug 2018