Polycystic Kidney Disease

Polycystic kidney disease (PKD) is a hereditary condition in which the kidneys develop multiple cysts. This leads to renal enlargement, distortion of the normal structure of the kidneys and functional impairment.

Polycystic Kidney Disease (PKD) Overview

Simple Kidney Cysts vs Polycystic Kidney Disease

Signs and Symptoms of Polycystic Kidney Disease

Diagnosis of Polycystic Kidney Disease (PKD)

Complications of Polycystic Kidney Disease (PKD)

Treatment of Polycystic Kidney Disease (PKD)

Genetics of Polycystic Kidney Disease (PKD)

Autosomal Dominant vs Autosomal Recessive Polycystic Kidney Disease (PKD)

Polycystic Kidney Disease vs. Acquired Cystic Kidney Disease

Non-Inherited Polycystic Kidney Disease

Latest Polycystic Kidney Disease News and Research

New FDA award fuels research into autosomal dominant tubulointerstitial kidney disease

Critical Path Institute (C-Path) is thrilled to announce its Polycystic Kidney Disease Outcomes Consortium (PKDOC) has been awarded an Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) focused Broad Agency Announcement (BAA) contract from the U.S. Food and Drug Administration (FDA).

24 Sep 2024

Addressing the challenges of polycystic kidney disease

Polycystic kidney disease (PKD) is an intractable disorder that causes fluid-filled cysts to grow in the kidneys. It is typically seen in adults. As one of the most prevalent hereditary kidney diseases, the autosomal dominant form of PKD is usually caused by mutations in the PKD1 and PKD2 genes.

11 Sep 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Gene therapy and glycoside drugs offer new hope for polycystic kidney disease treatment

Researchers have shown that dangerous cysts, which form over time in polycystic kidney disease (PKD), can be prevented by a single normal copy of a defective gene.

4 Apr 2024

Genetic analysis reveals hidden causes of chronic kidney disease in adults

Chronic kidney disease (CKD) is extremely prevalent among adults, affecting over 800 million individuals worldwide.

3 Apr 2024

Focusing on rare conditions could reduce kidney disease burden

Focusing on rare conditions could significantly reduce the burden of kidney disease on both patients and the NHS, according to a major new study led by UCL and the UK Kidney Association.

15 Mar 2024

Chronic underhydration linked to major health risks, study finds

Chronic underhydration has been linked to severe long-term health issues, including heart disease, diabetes, and kidney dysfunction, underscoring the need for increased hydration awareness and intervention strategies.

27 Feb 2024

Cancer drug holds promise for shrinking polycystic kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function.

22 Jan 2024

Ketogenic diet proved to be effective at controlling polycystic kidney disease

It's official: The ketogenic diet proved to be effective at controlling polycystic kidney disease (PKD) in the first randomized controlled clinical trial of ketogenic metabolic therapy for PKD.

11 Dec 2023

Coffee and genetics: A complex blend impacting kidney health

Researchers dive into the intricate connection between caffeine consumption and genetic predisposition, uncovering paradoxical effects on kidney function.

22 Oct 2023

UQ-led clinical trial to test the effectiveness of diabetes drug for polycystic kidney disease

Patient recruitment is underway for a University of Queensland-led clinical trial to test the effectiveness of a diabetes drug to slow the progression of polycystic kidney disease (PKD).

30 Aug 2023

Research provides new insights into the underlying disease mechanisms for polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease-;about a half million people in the United States alone suffer from the condition.

4 Apr 2023

Sugar appears to play a role in polycystic kidney disease, study finds

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

5 Jan 2023

Researchers develop a new approach to better understand the biology of polycystic kidney disease

A research team supported by the National Institutes of Health has developed a new approach to better understand the biology of polycystic kidney disease (PKD), an often-life-threatening genetic disorder that affects millions worldwide.

5 Jan 2023

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Organoids-;lab grown cells or tissues that resemble organs-;serve as a new tool for disease modeling, but researchers often have difficulty replicating the biophysical conditions in which the organs operate within the body.

22 Sep 2022

Study identifies a promising target for polycystic kidney disease treatment

Blocking the inhibition of PKD1 and PKD2 gene expression by deleting a binding site for microRNAs hindered the formation and growth of kidney cysts in autosomal dominant polycystic kidney disease (ADPKD) models, UT Southwestern researchers reported.

16 Sep 2022

Research provides a major step forward to growing human kidney in a dish

Kidney disease affects one in nine adults globally and the incidence of kidney failure is steadily rising around the world.

30 Aug 2022

Study uncovers an over-looked mechanism that likely contributes to autosomal dominant polycystic kidney disease

Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic condition that can lead to kidney failure and that has no cure.

13 Jul 2022

Ketogenic diets may help ward off polycystic kidney disease

The team of UC Santa Barbara biochemist Thomas Weimbs published the results of a clinical study that gives the first indication that ketogenic diets may be safe and effective in patients with polycystic kidney disease (PKD).

7 Jun 2022

New guidelines outline physical activities that are safe for dialysis patients

On dialysis for kidney failure and assume swimming or sit ups are out of the question? Think again. New international guidelines have been released on the eve of Kidney Health Week showing how important it is for dialysis patients to incorporate physical activity into their daily lives.

8 Mar 2022