Polycystic Kidney Disease News and Research

Latest Polycystic Kidney Disease News and Research

New insight into human ciliopathy

In the September 1st issue of G&D, Dr. Karen Oegema (UCSD) and colleagues identify the molecular basis of the lethal developmental disorder, hydrolethalus syndrome, and reveal that hydrolethalus syndrome actually belongs to the emerging class of human ciliopathy diseases.

4 Aug 2009

How cells control the great divide

A scientist whose work is key to understanding how cancer cells divide and spread in the body is to present advances in his latest research at a public forum to be held at the University of Leicester.

22 Apr 2009

Garden peas may help fight high blood pressure, kidney disease

Researchers in Canada are reporting that proteins found in a common garden pea show promise as a natural food additive or new dietary supplement for fighting high blood pressure and chronic kidney disease (CKD).

22 Mar 2009

Measuring quality of life in patients with hereditary kidney disease

A commonly used questionnaire that measures quality of life is not sensitive enough to pick up mental and physical problems experienced by patients with autosomal dominant polycystic kidney disease (ADPKD), according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).

4 Mar 2009

Researchers disrupt biochemical system involved in cancer, degenerative disease

Screening a chemical library of 200,000 compounds, researchers at UT Southwestern Medical Center have identified two new classes that can be used to study and possibly manipulate a cellular pathway involved in many types of cancer and degenerative diseases.

2 Feb 2009

Primary cilium's GPS-like cell structure crucial to wound repair

The primary cilium, the solitary, antenna-like structure that studs the outer surfaces of virtually all human cells, orient cells to move in the right direction and at the speed needed to heal wounds, much like a Global Positioning System helps ships navigate to their destinations.

17 Dec 2008

Potential gene target for treatment of common hearing, vertigo and balance problems

A UCLA study shows for the first time how microscopic crystals form sound and gravity sensors inside the inner ear.

30 Nov 2008

First NY to LA living-donor transplant chain results in three lifesaving kidney transplants at UCLA

The lives of three Los Angeles-area kidney transplant patients were transformed by one of the West Coast's first three-way living donor kidney transplant chains, made possible through the generosity of a non-directed, altruistic kidney donor from New York City -- announced today at a joint news conference.

4 Aug 2008

Potential new treatments for polycystic kidney disease

A family of small molecules called CFTR inhibitors show promising effects in slowing the progression of polycystic kidney disease (PKD), the most common genetic disease of the kidneys, according to preliminary research reported in the July 2008 issue of the Journal of the American Society Nephrology.

3 Apr 2008

Northwestern Memorial trial may wean kidney transplant patients off antirejection drugs

After a transplant surgery, anti-rejection drugs for the organ recipient are a must, but with prolonged use can have serious side effects, including infections, heart disease and cancer.

24 Jan 2008

New role discovered for cilia

Johns Hopkins researchers and colleagues have found a previously unrecognized role for tiny hair-like cell structures known as cilia: They help form our sense of touch.

22 Oct 2007

Chlamydomonas reinhardtii genome holds clues for renewable energy, the environment and human health

University of Minnesota researchers contributed to a national effort to sequence the genome of an ancient, one-celled organism that will help advance research in a broad range of areas, from biofuels to restoring the environment to understanding a variety of human diseases.

12 Oct 2007

Sex and gender in cardiovascular-renal physiology and pathophysiology

Gender influences the prevalence and progression rate of many renal diseases, such as polycystic kidney disease (PKD).

9 Aug 2007

Link between ciliary signaling and cancer

Submarines have periscopes. Insects have antennae. And increasingly, biologists are finding that most normal vertebrate cells have cilia, small hair-like structures that protrude like antennae into the surrounding environment to detect signals that control cell growth.

29 Jun 2007