Renal Cell Carcinoma News and Research

Latest Renal Cell Carcinoma News and Research

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Funded by a Specialized Program of Research Excellence award from the National Cancer Institute (NCI), the Kidney Cancer Program at UT Southwestern's Harold C. Simmons Comprehensive Cancer Center reports the largest and most diverse catalog of kidney cancer tumor models to date.

29 Nov 2021

Immune checkpoint inhibitor therapy results in longer treatment-free survival for patients with advanced renal cell carcinoma

Patients with advanced renal cell carcinoma who received the checkpoint inhibitor combination nivolumab (Opdivo) plus ipilimumab (Yervoy) experienced longer treatment-free survival (TFS) over a 42-month period than patients who received the targeted therapy sunitinib (Sutent), regardless of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) risk group, according to new analysis of the CheckMate-214 clinical trial.

10 Nov 2021

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

28 Oct 2021

Kidney cancer study provides new insights into tumor invasion and metastatic competence

How cancers metastasize remains poorly understood. The process begins when cancer cells break off from a tumor and invade blood and lymphatic vessels, the body's alleyways. But studying invasion - typically a microscopic process - is challenging.

20 Oct 2021

Underexpression of specific metabolic enzyme is a common feature in kidney cancer, study shows

A team of investigators has discovered that the underexpression of a specific metabolic enzyme is a common and adverse epigenetic modulating feature in clear cell renal cell carcinoma (ccRCC), according to a recent study published in Proceedings of the National Academy of Sciences.

20 Oct 2021

Researchers explore the impact of venous thromboembolism during surgery for renal cell carcinoma

Venous thromboembolism (VTE) refers to blood clots in the veins, which is a serious yet preventable medical condition and is often seen with advanced cancers.

14 Sep 2021

Analysis finds untapped potential for immunotherapy in older cancer patients

A retrospective analysis of large datasets of biomarkers from tumors and healthy tissue by researchers at the Johns Hopkins Kimmel Cancer Center Convergence Institute suggests that older cancer patients could benefit as much as younger patients from cancer immunotherapies.

13 Sep 2021

Cancer immunotherapies could benefit older patients as much as younger people

7 Sep 2021

Penn study discovers a targetable vulnerability in clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) cells can be destroyed and kept from multiplying by inhibiting the HDL cholesterol receptor SCARB1, according to research from the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2021

Study may provide a new therapeutic target for treatment of LUAD patients

Aging-US published "A novel ferroptosis-related gene signature for prognostic prediction of patients with lung adenocarcinoma" which reported that RNA-seq transcriptome data of LUAD patients were obtained from The Cancer Genome Atlas database.

9 Aug 2021

New radiotracer opens the door for advancement of iron-targeted cancer therapies

A new radiotracer that detects iron in cancer cells has proven effective, opening the door for the advancement of iron-targeted therapies for cancer patients.

23 Jul 2021

Clinical trial demonstrates safety of new approach to treat invasive kidney cancer

A new approach using precisely targeted, high-dose radiation to treat invasive kidney cancer proves safe, based on a clinical trial by the UT Southwestern Harold C. Simmons Comprehensive Cancer Center's kidney cancer program. The study, published in the International Journal of Radiation Oncology*Biology*Physics, could offer new hope for patients with a historically dismal condition.

29 Jun 2021

Researchers identify the origins of seven types of kidney cancer

The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH), the Princess Máxima Center for Pediatric Oncology and Oncode Institute.

24 Jun 2021

Using natural killers from the immune system to target breast cancer cells

It sounds like a plot from a Quentin Tarantino movie -- something sets off natural killers and sends them on a killing spree.

16 Jun 2021

New study could help guide oncologists in selecting the best treatment for kidney cancers

Not all kidney cancers behave the same, with wildly different responses to immunotherapy or other treatments – and wildly different outcomes for patients as a result.

8 Jun 2021

Advanced-stage kidney cancer more common in Hispanic and Native Americans in Arizona

Recently published research from the University of Arizona Health Sciences shows that advanced-stage kidney cancer is more common in Hispanic Americans and Native Americans than in non-Hispanic whites, and that both Hispanic Americans and Native Americans in Arizona have an increased risk of mortality from the disease.

6 May 2021

FDA issues noncompliance notice for failing to submit clinical trial summary results to ClinicalTrials.gov

Being transparent about the results of completed clinical trials enables important advances in the development of medical products and helps ensure a safe, effective and efficient clinical research enterprise.

28 Apr 2021

Baseline brain imaging should be considered in most metastatic kidney cancer patients, study suggests

The April 2021 issue of JNCCN - Journal of the National Comprehensive Cancer Network publishes new research from Memorial Sloan Kettering Cancer Center (MSK) and Gustave Roussy Institute, which suggests that baseline brain imaging should be considered in most patients with metastatic kidney cancer.

13 Apr 2021

Cancer patients treated with immunotherapy at high risk of developing thrombotic complications

In a study recently published in the leading journal "Blood", Florian Moik and Cihan Ay from the Division of Hematology and Hemastasology of the Department of Medicine I of MedUni Vienna/Vienna General Hospital, working in collaboration with the Division of Oncology, the Department of Dermatology and the dispensary of Vienna General Hospital, provided preliminary data on the incidence, risk factors and clinical outcomes of thrombotic complications in this new form of cancer treatment.

31 Mar 2021

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Altered cellular energetics, a hallmark of cancers, has been associated with obesity. However, links between systemic energy regulation and aberrant cancer cell metabolism have been lacking.

25 Mar 2021

Renal Cell Carcinoma News and Research

Latest Renal Cell Carcinoma News and Research

SPORE-funded Kidney Cancer Program at UT Southwestern reports wide array of tumor models to date

Immune checkpoint inhibitor therapy results in longer treatment-free survival for patients with advanced renal cell carcinoma

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Kidney cancer study provides new insights into tumor invasion and metastatic competence

Underexpression of specific metabolic enzyme is a common feature in kidney cancer, study shows

Researchers explore the impact of venous thromboembolism during surgery for renal cell carcinoma

Analysis finds untapped potential for immunotherapy in older cancer patients

Cancer immunotherapies could benefit older patients as much as younger people

Penn study discovers a targetable vulnerability in clear cell renal cell carcinoma

Study may provide a new therapeutic target for treatment of LUAD patients

New radiotracer opens the door for advancement of iron-targeted cancer therapies

Clinical trial demonstrates safety of new approach to treat invasive kidney cancer

Researchers identify the origins of seven types of kidney cancer

Using natural killers from the immune system to target breast cancer cells

New study could help guide oncologists in selecting the best treatment for kidney cancers

Advanced-stage kidney cancer more common in Hispanic and Native Americans in Arizona

FDA issues noncompliance notice for failing to submit clinical trial summary results to ClinicalTrials.gov

Baseline brain imaging should be considered in most metastatic kidney cancer patients, study suggests

Cancer patients treated with immunotherapy at high risk of developing thrombotic complications

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Free guide - everything about renal proximal tubule cells eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

Renal Cell Carcinoma News and Research

Latest Renal Cell Carcinoma News and Research

Free guide - everything about renal proximal tubule cells eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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