Renal Cell Carcinoma News and Research

Latest Renal Cell Carcinoma News and Research

ZHX2 protein could offer a new treatment strategy for kidney cancer

University of North Carolina Lineberger Comprehensive Cancer Center scientists have uncovered a potential therapeutic target for kidney cancers that have a common genetic change.

20 Jul 2018

Cancer patients receiving anti-PD-1 therapies may experience delayed skin reactions

Cancer patients receiving anti-PD-1 therapies who develop lesions, eczema, psoriasis, or other forms of auto-immune diseases affecting the skin may experience those adverse reactions on a delay – sometimes even after treatment has concluded.

19 Jul 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

An analysis of lymph node dissection in renal cell carcinoma that has not spread to other organs indicates the procedure is often performed for stage 1 disease and shows no overall survival benefit.

21 May 2018

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.

10 May 2018

Non-aspirin NSAID use linked to shorter survival in patients with metastatic renal cell carcinoma

Ibuprofen, aspirin, and other non-steroidal anti-inflammatory medications are among the most commonly utilized medications in the United States. Primarily for treating pain, inflammation, and preventing cardiovascular disease, NSAIDs' promising anti-cancer properties have been highlighted by a growing body of data in recent years.

2 May 2018

Study finds link between industry payments and prescription practices for two cancer types

Physicians who received payment from pharmaceutical companies for meals, talks and travel were more likely to prescribe those companies' drugs for two cancer types, a University of North Carolina Lineberger Comprehensive Cancer Center-led study has found.

9 Apr 2018

Immunotherapy combination increases overall survival in people with kidney cancer, study shows

Treating people with advanced metastatic kidney cancer using a combination of the immunotherapy drugs nivolumab (Opdivo) and ipilimumab (Yervoy) significantly increased overall survival versus treatment with sunitinib (Sutent) alone, according to new findings from researchers at Memorial Sloan Kettering Cancer Center that were reported today in the New England Journal of Medicine.

22 Mar 2018

Oncolytic virus alerts the immune system to attack tumors

A new UC San Francisco study has shown that a cancer-killing virus currently in clinical trials may function as a cancer vaccine - in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumor, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region.

14 Feb 2018

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

The U.S. Food and Drug Administration today approved Sutent (sunitinib malate) for the adjuvant treatment of adult patients who are at a high risk of kidney cancer (renal cell carcinoma) returning after a kidney has been removed (nephrectomy).

17 Nov 2017

New study describes unique role of androgens in kidney cancer

A new study is believed to be the first to describe the unique role of androgens in kidney cancer, and it suggests that a new approach to treatment, targeting the androgen receptor (AR), is worth further investigation.

13 Oct 2017

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

FDA grants approval for new biosimilar to treat multiple types of cancer

The U.S. Food and Drug Administration today approved Mvasi (bevacizumab-awwb) as a biosimilar to Avastin (bevacizumab) for the treatment of multiple types of cancer. Mvasi is the first biosimilar approved in the U.S. for the treatment of cancer.

14 Sep 2017

Combination immunotherapy shows better overall survival in kidney cancer patients

A combination immunotherapy treatment showed better overall survival in patients with previously untreated advanced or metastatic renal cell carcinoma than current therapy, according to results from a phase 3 clinical trial presented at the Presidential Symposium of the European Society for Medical Oncology's 2017 Congress in Spain.

13 Sep 2017

Penn researcher wins National Cancer Institute Outstanding Investigator Award

M. Celeste Simon, PhD, who studies cancer cell metabolism, tumor immunology, and the influence of oxygen availability and deprivation on tumor growth, has been given a National Cancer Institute Outstanding Investigator Award.

8 Sep 2017

Review of kidney cancer incidence in California signals end of a trend

A review of kidney cancer in California from 1988 through 2013 by the UC Davis Institute for Population Health Improvement has concluded that the high incidence of small tumors and early-stage disease observed in California from 1988 until about 2009 has declined and stabilized in recent years, signaling the end of a trend.

18 Aug 2017

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

A new cooperative research study including Norris Cotton Cancer Center's Lionel Lewis, MB BCh, MD, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with metastatic renal cell cancer (mRCC).

26 Jul 2017

Experimental drug benefits some patients with advanced kidney cancer

Some patients with a form of advanced kidney cancer that carries a poor prognosis benefited from an experimental drug targeted to an abnormal genetic pathway causing cancerous growth, according to research led by a Dana-Farber Cancer Institute scientist.

24 Jun 2017

Blocking newly discovered cellular pathway could help control tumor growth

Scientists have discovered a new cellular pathway that can promote and support the growth of cancer cells. In a mouse model of melanoma, blocking this pathway resulted in reduction of tumor growth.

15 Jun 2017

Renal Cell Carcinoma News and Research

Latest Renal Cell Carcinoma News and Research

ZHX2 protein could offer a new treatment strategy for kidney cancer

Cancer patients receiving anti-PD-1 therapies may experience delayed skin reactions

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Analysis of lymph node dissection shows no overall survival benefit in renal carcinoma patients

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Non-aspirin NSAID use linked to shorter survival in patients with metastatic renal cell carcinoma

Study finds link between industry payments and prescription practices for two cancer types

Immunotherapy combination increases overall survival in people with kidney cancer, study shows

Oncolytic virus alerts the immune system to attack tumors

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

New study describes unique role of androgens in kidney cancer

First-ever treatment for Merkel cell carcinoma receives approval in Japan

FDA grants approval for new biosimilar to treat multiple types of cancer

Combination immunotherapy shows better overall survival in kidney cancer patients

Penn researcher wins National Cancer Institute Outstanding Investigator Award

Review of kidney cancer incidence in California signals end of a trend

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

Experimental drug benefits some patients with advanced kidney cancer

Blocking newly discovered cellular pathway could help control tumor growth

Free guide - everything about renal proximal tubule cells eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

Renal Cell Carcinoma News and Research

Latest Renal Cell Carcinoma News and Research

Free guide - everything about renal proximal tubule cells eBook

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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