Scleroderma News and Research

Latest Scleroderma News and Research

Translational research training program helps students to better understand patients' problems

Translational research aims to speed research breakthroughs into the clinic. And yet, training for basic scientists and clinicians too often remains siloed, leading to divergent cultures and a loss of opportunity for cross-disciplinary collaboration.

26 Sep 2020

Research uncovers potential cause of neurotoxicity due to immunotherapy

New research has uncovered the previously unknown presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).

21 Sep 2020

Study sheds wider light on the clinical profile of patients with pulmonary hypertension

When most people think of high blood pressure, they think of being tested with an arm cuff at a doctor's appointment. That type of blood pressure is separate from pulmonary hypertension (PH), which is high blood pressure in the lung arteries.

28 Jul 2020

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

A study by investigators at Hospital for Special Surgery has discovered a molecule in the lymphatic system that has the potential to play a role in autoimmune disease.

22 Mar 2020

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.

11 Dec 2019

BU researcher receives NIH grant for clinical research in rheumatology

David Felson, MD, MPH, professor of medicine and epidemiology at Boston University Schools of Medicine and Public Health, was awarded a National Institute of Health P30 Center Grant.

15 Oct 2019

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

An international, multicenter phase II clinical trial is evaluating the efficacy and safety of mavrilimumab co-administered with a 26-week corticosteroid taper in patients with giant cell arteritis.

26 Sep 2019

Survey says half of people with rheumatoid disease struggle to pay for treatment

Rheumatoid disease encompasses inflammatory conditions that affect the joints, muscle, bones, and organs. A new study found that despite 90 of patients have health insurance, nearly 60 percent said that they are struggling to afford medication or treatment in the last year.

16 Sep 2019

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings.

From Johns Hopkins Medicine 13 Sep 2019

FDA approves first drug to treat patients with rare lung condition

The U.S. Food and Drug Administration today approved Ofev (nintedanib) capsules to slow the rate of decline in pulmonary function in adults with interstitial lung disease associated with systemic sclerosis or scleroderma, called SSc-ILD. It is the first FDA-approved treatment for this rare lung condition.

7 Sep 2019

Elevated estrogen levels associated with more severe disease in scleroderma

Estrogen is the quintessentially female hormone. It is surprising, then, that a Medical University of South Carolina study found that a type of estrogen, estradiol, was more abundant in older men with scleroderma than in postmenopausal women with the disease.

6 Jun 2019

Newly identified internal regulator helps control body's response to fight infection

Scientists have identified a new internal regulator which helps control the body's response to fight infection.

30 May 2019

Finding potential treatments for autoimmune diseases

More than 50 million Americans are affected by an autoimmune disease, with women at an increased risk for developing one.

7 May 2019

Suppressing cancer-causing protein could correct increased fibrosis in scleroderma patients

A protein known to play a role in cancer may also be increasing fibrosis in scleroderma patients.

27 Feb 2019

MUSC researchers identify potential therapeutic target for lung fibrosis

In an article published online by Frontiers in Endocrinology, researchers at the Medical University of South Carolina report that they have identified a potential therapeutic target for lung fibrosis or scarring.

19 Dec 2018

Silicone breast implants may increase risk of rare adverse outcomes in women

Women receiving silicone breast implants may be at increased risk of several rare adverse outcomes compared to the general population, reports a study in Annals of Surgery.

18 Sep 2018

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal organs.

30 Aug 2018

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Dr. Lesley Ann Saketkoo, an associate professor of clinical medicine at Tulane University School of Medicine, has been named Doctor of the Year by the Scleroderma Foundation. The award recognizes leadership and commitment to the community battling scleroderma, a disabling and life-limiting multi-organ autoimmune disease with progressive lung, heart, kidney, gastrointestinal tract and/or vascular involvement.

21 Aug 2018

Seeking solutions to treat scleroderma

It begins with cold hands. Not just put-on-some-gloves cold. Instead, the fingers overreact to cold by turning white or blue and may become numb or tingly.

17 Aug 2018

Researchers find experimental compound to treat fibrotic diseases

Normal scar tissue forms to heal an internal wound and quietly retreats when the job is done. But in many common diseases - kidney, liver and lung fibrosis -- the scar tissue goes rogue and strangles vital organs. These diseases are largely untreatable and ultimately fatal.

13 Jul 2018

Scleroderma News and Research

Latest Scleroderma News and Research

Translational research training program helps students to better understand patients' problems

Research uncovers potential cause of neurotoxicity due to immunotherapy

Study sheds wider light on the clinical profile of patients with pulmonary hypertension

Newly discovered molecule in the lymphatic system could play a role in autoimmune diseases

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

BU researcher receives NIH grant for clinical research in rheumatology

Clinical trial to evaluate efficacy and safety of new treatment for giant cell arteritis

Survey says half of people with rheumatoid disease struggle to pay for treatment

Failed cancer drug could potentially be used to treat fibrotic diseases and scleroderma

FDA approves first drug to treat patients with rare lung condition

Elevated estrogen levels associated with more severe disease in scleroderma

Newly identified internal regulator helps control body's response to fight infection

Finding potential treatments for autoimmune diseases

Suppressing cancer-causing protein could correct increased fibrosis in scleroderma patients

MUSC researchers identify potential therapeutic target for lung fibrosis

Silicone breast implants may increase risk of rare adverse outcomes in women

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Scleroderma Foundation names Tulane professor as 'Doctor of the Year'

Seeking solutions to treat scleroderma

Researchers find experimental compound to treat fibrotic diseases

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Scleroderma News and Research

Latest Scleroderma News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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