Sepsis

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Everything You Need To Know About Sepsis

Sepsis is a life-threatening systemic response to an infection. This article provides an overview of sepsis, including stages, diagnosis and treatment.

Sepsis Diagnosis

Causes and Symptoms of Sepsis in Newborns

Diagnosis and Treatment of Sepsis in Newborns

Sepsis Prevention

Recovering from Sepsis

Sepsis Epidemiology

Sepsis Pathophysiology

Sepsis at the Molecular Level

Sepsis and Pregnancy

Sepsis: Identifying the Signs and Administering First Aid

Acute Respiratory Distress Syndrome (ARDS) and Sepsis

See more featured articles »

Sepsis Complications and Prevention

The Stages of Sepsis

How Antimicrobial Resistance Amplifies the Burden of Sepsis

Lactate Levels and Sepsis

Sepsis and Influenza

Sepsis History

The Development of a Sepsis Scoring System in a Murine Model

Latest Sepsis News and Research

Ozone therapy shows promise in treating sepsis-induced lung injury

Sepsis, a severe and often fatal complication of infection, is a leading cause of both ALI and acute respiratory distress syndrome (ARDS).

27 Dec 2024

New prediction model improves early detection of infected pancreatic necrosis

A new prediction model for infected pancreatic necrosis (IPN) in patients with acute pancreatitis (AP) offers a groundbreaking approach to improving patient outcomes.

20 Dec 2024

AI-driven tool revolutionizes placenta examination at bedside

The placenta, the temporary organ grown to support fetal development, plays a vital role during pregnancy and contains crucial information about the health of both the parent and the baby.

17 Dec 2024

Breakthrough discovery could lead to effective vaccine for S. aureus

Staphylococcus aureus (S. aureus) is a major cause of skin and soft tissue infections that can sometimes lead to sepsis and toxic shock syndrome.

16 Dec 2024

AI tool could revolutionize placenta examination and improve neonatal care

A newly developed tool that harnesses computer vision and artificial intelligence (AI) may help clinicians rapidly evaluate placentas at birth, potentially improving neonatal and maternal care, according to new research from scientists at Northwestern Medicine and Penn State.

14 Dec 2024

New biomarker testing protocol could shorten antibiotic treatment for sepsis

A major UK patient trial of a new biomarker testing protocol for sepsis, led by University of Manchester researchers, has shown it is possible to safely stop antibiotic treatment earlier than current care.

10 Dec 2024

Potential new treatment for motor neurone disease shows promising results

A potential new treatment for motor neurone disease (MND) developed by a company spun-out of The University of Queensland has produced successful results in a human clinical trial.

9 Dec 2024

Vancouver study reveals surge in severe Shigella cases in homeless population

A recent study published in Clinical Infectious Diseases has uncovered an increase in severe multidrug-resistant (MDR) Shigella sonnei infections, particularly among people experiencing homelessness (PEH) in Vancouver, Canada.

6 Dec 2024

Study reveals non-invasive technique for early detection of sepsis

Clinicians lack methods for early detection of sepsis, a dysregulated response to infection that can result in life-threatening organ failure if treatment is delayed.

4 Dec 2024

Type 2 diabetes doubles infection-related mortality and exposes gaps in health reporting

People with type 2 diabetes face a significantly higher risk of infection-related deaths, particularly in younger age groups, with infections accounting for 13% of deaths compared to 1.2% in conventional records.

3 Dec 2024

Upcoding practices by hospitals lead to billions in extra payments

In five states over nearly a decade, hospitals have increased how frequently they document patients as needing the highest intensity care, which has led to hospitals receiving billions in extra payments from health plans and government programs, according to a new RAND study.

3 Dec 2024

Nanozyme breakthrough offers new hope for viral pneumonia treatment

A recent study in Nature Materials introduces an inhalable nanozyme treatment for viral pneumonia, showing promising results in reducing inflammation and viral load in various mouse models. The nanozyme, CeTA-K1tkP, demonstrates broad-spectrum effects and biocompatibility, offering a potential new approach to treating pneumonia and other inflammatory conditions.

3 Dec 2024

Researchers expose practices of crisis pregnancy centers across the U.S.

A new study from scientists at the University of California San Diego introduces a powerful new approach to understanding the operation of crisis pregnancy centers, non-profit organizations dedicated to an anti-abortion agenda.

2 Dec 2024

New study explores obecabtagene autoleucel for adults with hard-to-treat leukemia

FELIX study results reveal obe-cel's potential in relapsed B-cell ALL, achieving 77% remission with low severe toxicity, enhancing CAR T-cell therapy outcomes.

2 Dec 2024

Study provides insights into trends and disparities of neonatal infectious diseases in LMICs

Researchers from Peking University have conducted an in-depth study on the epidemic status, secular trends, and risk factors of 15 common neonatal infectious diseases across low- and middle-income countries (LMICs) from 1990 to 2019.

19 Nov 2024

HMGB1 as a key mediator in liver disease pathogenesis

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates.

8 Nov 2024

HNL Dimer as a promising biomarker for monitoring antibiotic treatment in sepsis

The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis.

8 Nov 2024

SpaceX CRS-31 supports heart health, neurodegeneration, and student science

More than 25 payloads sponsored by the International Space Station (ISSInternational Space Station) National Laboratory, including technology demonstrations, in-space manufacturing, student experiments, and multiple projects funded by the U.S. National Science Foundation (NSF), are bound for the orbiting outpost.

4 Nov 2024

AI provides same-day assessments of antimicrobial resistance in ICUs

Artificial intelligence (AI) can provide same-day assessments of antimicrobial resistance for patients in intensive care – critical to preventing life-threatening sepsis.

1 Nov 2024

Researchers identify 4-gene signature to predict neonatal sepsis before symptoms

The study uncovers gene expression signatures that predict neonatal sepsis, highlighting the potential for early intervention to reduce mortality in infants.

31 Oct 2024