Sepsis

Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

Everything You Need To Know About Sepsis

Sepsis is a life-threatening systemic response to an infection. This article provides an overview of sepsis, including stages, diagnosis and treatment.

Sepsis Diagnosis

Causes and Symptoms of Sepsis in Newborns

Diagnosis and Treatment of Sepsis in Newborns

Sepsis Prevention

Recovering from Sepsis

Sepsis Epidemiology

Sepsis Pathophysiology

Sepsis at the Molecular Level

Sepsis and Pregnancy

Sepsis: Identifying the Signs and Administering First Aid

Acute Respiratory Distress Syndrome (ARDS) and Sepsis

See more featured articles »

Sepsis Complications and Prevention

The Stages of Sepsis

How Antimicrobial Resistance Amplifies the Burden of Sepsis

Lactate Levels and Sepsis

Sepsis and Influenza

Sepsis History

The Development of a Sepsis Scoring System in a Murine Model

Latest Sepsis News and Research

Study provides insights into trends and disparities of neonatal infectious diseases in LMICs

Researchers from Peking University have conducted an in-depth study on the epidemic status, secular trends, and risk factors of 15 common neonatal infectious diseases across low- and middle-income countries (LMICs) from 1990 to 2019.

19 Nov 2024

HMGB1 as a key mediator in liver disease pathogenesis

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates.

8 Nov 2024

HNL Dimer as a promising biomarker for monitoring antibiotic treatment in sepsis

The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis.

8 Nov 2024

SpaceX CRS-31 supports heart health, neurodegeneration, and student science

More than 25 payloads sponsored by the International Space Station (ISSInternational Space Station) National Laboratory, including technology demonstrations, in-space manufacturing, student experiments, and multiple projects funded by the U.S. National Science Foundation (NSF), are bound for the orbiting outpost.

4 Nov 2024

AI provides same-day assessments of antimicrobial resistance in ICUs

Artificial intelligence (AI) can provide same-day assessments of antimicrobial resistance for patients in intensive care – critical to preventing life-threatening sepsis.

1 Nov 2024

Researchers identify 4-gene signature to predict neonatal sepsis before symptoms

The study uncovers gene expression signatures that predict neonatal sepsis, highlighting the potential for early intervention to reduce mortality in infants.

31 Oct 2024

Machine learning reveals distinct clinical states in pneumonia patients

Two patients being treated for pneumonia, an infection that causes difficulty breathing due to fluid-filled sacs in the lungs, can look vastly different and have opposing outcomes. Yet doctors struggle to accurately predict patients' prognoses and determine the most effective treatments.

29 Oct 2024

Genetic marker could revolutionize neonatal sepsis diagnosis

A genetic signature in newborns can predict neonatal sepsis before symptoms even start to show, according to a new study.

29 Oct 2024

Researchers decode MRSA biofilm structure to combat antibiotic resistance

Imagine falling seriously ill with an infection. Normally, we visit the doctor, are prescribed antibiotics, and after 7-10 days, we're back on our feet.

24 Oct 2024

New technology enables targeted delivery of antibiotics

Researchers from the University of Waterloo have developed a new technology that can hold an entire course of antibiotics in one tiny dose and deliver on demand just the right amount of medication that a particular patient needs to fight an infection.

24 Oct 2024

Study links gut bacteria infection to Alzheimer's disease progression

A groundbreaking study by researchers at Florida State University's Gut Biome Lab has revealed a potential link between an infection caused by gut bacteria and the progression of Alzheimer's disease.

24 Oct 2024

Research reveals AI's potential to transform hospital reporting processes

A pilot study led by researchers at University of California San Diego School of Medicine found that advanced artificial intelligence (AI) could potentially lead to easier, faster and more efficient hospital quality reporting while retaining high accuracy, which could lead to enhanced health care delivery.

21 Oct 2024

FDA strengthens AI regulation to ensure patient safety and innovation in healthcare

The FDA is adapting regulations to manage AI’s rapid development in healthcare, focusing on patient safety and the life cycle of AI tools. This review emphasizes the need for continuous monitoring to ensure AI performs effectively in clinical settings.

16 Oct 2024

Half of sepsis patients face death within two years

Half of all patients with sepsis admitted to an emergency medical department died within two years, according to Danish researchers investigating factors that could predict outcomes for these patients.

14 Oct 2024

Spatiotemporal trends in maternal deaths and mortality surveillance

Analysis reveals that misclassified maternal fatalities may distort US mortality statistics, emphasizing the importance of accurate death certificate reporting.

9 Oct 2024

New X-ray technique reveals metal ion role in antibiotic efficacy

Researchers from City St George's, University of London have used a new ultra-high precision x-ray scattering technique to unveil the location and identity of metal ions in bacteria that are crucial for antibiotics to work optimally.

4 Oct 2024

Breast milk antibodies linked to protection against rotavirus in infants

A study led by researchers at the University of Rochester Medical Center found that breast milk provides protection against rotavirus, a common gastrointestinal disease that causes diarrhea, vomiting and fever in infants.

1 Oct 2024

Diagnostic errors affecting one in fourteen hospital patients

Harmful diagnostic errors may be occurring in as many as 1 in every 14 (7%) hospital patients-;at least those receiving general medical care-;suggest the findings of a single center study in the US, published online in the journal BMJ Quality & Safety.

1 Oct 2024

New mechanism uncovered behind immune decline after tuberculosis treatment

Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.

1 Oct 2024

High magnesium levels drive higher mortality in sepsis patients

Study identifies high serum magnesium levels as a significant factor associated with increased mortality in sepsis patients, demonstrating a dose-response relationship across diverse patient cohorts. It highlights magnesium as a potential marker for risk stratification in sepsis.

30 Sep 2024