Sepsis News and Research

Latest Sepsis News and Research

COVID-19's impact on maternal mortality demands rethink of public health strategies

During the peak of the SARS-CoV-2 pandemic, there was an increase in maternal mortality in Chile. This is confirmed by a natural population experiment based on data from the Department of Health Statistics and Information (DEIS) of the Chilean Ministry of Health. The research was published in PLOS Global Public Health.

23 Jul 2024

Novel method enables RNA detection with Cas12 nucleases

CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

17 Jul 2024

AI model boosts cancer gene prediction and patient prognosis

The artificial intelligence (AI) model GPT-4, known from its application in ChatGPT, shows impressive capabilities in biomedical research and can be used in many ways for simulations. A simulator developed at MedUni Vienna and based on GPT-4 shows increased accuracy in classifying the importance of genes in cancer cells, as well as in the prognosis of cancer patients. The results of the study were published in the journal Computers in Biology and Medicine.

12 Jul 2024

Real-world data confirms safety of RSV vaccination in late pregnancy

Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

8 Jul 2024

Mapping pathogen spread and evolution using genomic and human mobility data

A new way to map the spread and evolution of pathogens, and their responses to vaccines and antibiotics, will provide key insights to help predict and prevent future outbreaks.

3 Jul 2024

Expert orthopedic surgeon saves man’s leg from being amputated after damage from advanced cancer

Richard Monti, a father of six and a real estate developer on Long Island, thought that his metastatic kidney cancer diagnosis would be the toughest battle to endure in his life.

21 Jun 2024

Drug-related infant deaths surge in the U.S., study finds

A recent study from the Journal of Perinatal Medicine reveals a significant rise in drug-related infant deaths in the U.S. between 2018 and 2022, highlighting the urgent need for targeted interventions.

18 Jun 2024

Personalized medicine approaches for sepsis based on immune response profiling

Sepsis patients could be treated based on their immune system's response to infection, not their symptoms.

18 Jun 2024

Researchers develop cutting-edge smart bandages for improved wound healing

Chronic wounds, which include diabetic ulcers, surgical wounds, pressure injuries, and other problems, are deadlier than many people realize.

17 Jun 2024

MEK inhibitor trametinib shows potential in pediatric JMML treatment

The MEK inhibitor trametinib (Mekinist) was an effective treatment for pediatric patients with relapsed or refractory juvenile myelomonocytic leukemia (JMML) enrolled in a phase II clinical trial, with seven of 10 patients alive after a median of two years.

13 Jun 2024

Changing antibiotic delivery method improves sepsis outcomes globally

Changing the way antibiotics are given to adult patients with sepsis will save thousands of lives a year globally, according to research by The University of Queensland and The George Institute for Global Health.

12 Jun 2024

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in Microbiology Spectrum, a journal of the American Society for Microbiology.

12 Jun 2024

Precision medicine in sepsis care: Identifying and treating the PHES subgroup in children

Sepsis – the leading cause of mortality in children around the world – can present with a wide range of signs and symptoms, making a one-size-fits-all treatment strategy ineffective.

11 Jun 2024

Novel insights into the underlying, contributing, and direct causes of death in Australia

Coronary heart disease (CHD) was involved in 1 in 5 deaths in 2022 when using all of the information included on the medical death certificate, according to a new Australian Institute of Health and Welfare (AIHW) release revealing what Australians are most likely to die from.

8 Jun 2024

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Bacteria, parasites, viruses-;the immune system tackles them all. At the front line of the human immune response are cells called macrophages, which are responsible for correctly identifying intruders and then directing how the entire immune system responds.

5 Jun 2024

Study challenges use of in-hospital mortality as sepsis quality metric for safety-net hospitals

Sepsis is a leading cause of death and disability and a key target of state and federal quality measures for hospitals.

31 May 2024

Notre Dame study identifies high-risk population for CAUTIs due to fibrinolytic deficiencies

Urinary catheters are required for nearly every surgical procedure. However, a major challenge for the health care industry is predicting who may develop catheter-associated urinary tract infections (CAUTIs) and when these infections may lead to death.

30 May 2024

New antibiotic lolamicin shows promise in fighting drug-resistant infections

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.

29 May 2024

UMSOM receives $3.96 million grant for maternal vaccine against neonatal sepsis

University of Maryland School of Medicine (UMSOM) researchers at the Center for Vaccine Development and Global Health (CVD) have been awarded $3.96 million to develop a maternal vaccine that prevents sepsis caused by Klebsiella pneumoniae in newborns and infants.

23 May 2024

Labor epidurals linked to lower risk of severe maternal morbidity

Having an epidural during labor is associated with a marked reduction in serious complications in the first few weeks after giving birth, finds a study published by The BMJ today.

22 May 2024