Sepsis News and Research

Latest Sepsis News and Research

First new antibiotic class in decades discovered using explainable AI platform

Scientists have discovered one of the first new classes of antibiotics identified in the past 60 years, and the first discovered leveraging an AI-powered platform built around explainable deep learning.

20 Dec 2023

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

COVID-19 significantly raises risk of severe complications in pregnant women

Study found that pregnant mothers with COVID-19 face a significantly higher risk of severe maternal morbidity (SMM), including adult respiratory distress syndrome and acute renal failure, emphasizing the urgent need for their early diagnosis and treatment.

10 Dec 2023

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

The clinical significance of Streptococcus agalactiae (Group B Streptococcus; GBS) deoxyribonucleic acid (DNA) in the placenta.

4 Dec 2023

Balanced IV fluids can reduce death risk for critically ill patients

Results of a new meta-analysis in shows that intravenous fluid (IV) therapy using balanced solutions rather than commonly used saline can reduce the risk of in-hospital death of critically ill patients by four percent.

30 Nov 2023

The impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome

Researchers from the United Kingdom evaluated the use of a high-sensitivity assay to measure cardiac troponin I and its impact on myocardial infarction (MI) risk or other long-term outcomes such as death at five years in individuals with suspected acute coronary syndrome.

30 Nov 2023

Associations between socioeconomic status, clinical variables, and non-COVID-19 sepsis risk

The impact of socioeconomic status and clinical variables on sepsis incidence and mortality.

28 Nov 2023

Novel AI-powered method detects antimicrobial resistance within 30 minutes

To mark World Antimicrobial Awareness Week, researchers supported by the Oxford Martin Programme on Antimicrobial Resistance Testing (University of Oxford) have reported advances towards a novel and rapid antimicrobial susceptibility test that can return results within as little as 30 minutes.

22 Nov 2023

Green tea-silver nanoparticles: A promising weapon against superbugs

Once upon a time, people believed to be invincible against bacterial diseases, thanks to the antibiotics. Does this sound like a fairy tale? By all means! Nothing could be further from the truth.

17 Nov 2023

Latest surveillance data shows a rise in antibiotic resistant infections and associated deaths

The latest national surveillance data, announced at the UK Health Security Agency (UKHSA) annual conference in Leeds today, shows that an estimated 58,224 people in England had an antibiotic resistant infection in 2022 - a rise of 4% since 2021 (55,792).

15 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

BMI should not be used to determine eligibility for gender-affirming chest surgery

Body mass index, or BMI, is a person's mass (weight) in kilograms divided by the square of their height in meters.

7 Nov 2023

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

This research paper delves into the risks of contamination in ready-to-eat fruits and vegetables by enteric pathogens like E. coli, Salmonella, and Listeria, which can lead to foodborne illnesses. It also explores the contamination sources and plant-pathogen interactions, emphasizing the importance of improved safety measures in the food supply chain.

6 Nov 2023

Study exposes gaps in pediatric antibiotic effectiveness in Southeast Asia, calls for tailored treatments

A study in The Lancet Regional Health exposes significant gaps in the effectiveness of WHO-recommended antibiotic regimens for serious infections in Southeast Asian and Pacific children, underscoring the urgent need for region-specific treatment guidelines to combat rising antimicrobial resistance.

5 Nov 2023

Microscopic inflammation in IBD linked to higher risk of serious infections

Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.

1 Nov 2023

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

The lungs were once at the forefront of SARS-Cov-2 research, but as reports of organ failure and other serious complications poured in, scientists set out to discover how and why the respiratory virus was causing serious damage to the body's major organs, including the lungs.

31 Oct 2023

Antibiotics no longer effective in treating childhood infections in large parts of the world

Drugs to treat common infections in children and babies are no longer effective in large parts of the world, due to high rates of antibiotic resistance.

31 Oct 2023

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

A four-year, $3.4 million grant to investigate molecular mechanisms and therapeutic treatments for acute respiratory distress syndrome (ARDS) has been awarded to UTHealth Houston researchers by the National Heart, Lung, and Blood Institute, part of the National Institutes of Health.

26 Oct 2023

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies.

25 Oct 2023

Sepsis News and Research

Latest Sepsis News and Research

First new antibiotic class in decades discovered using explainable AI platform

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

COVID-19 significantly raises risk of severe complications in pregnant women

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

Balanced IV fluids can reduce death risk for critically ill patients

The impact of implementing a high sensitivity assay for cardiac troponin I on long term outcomes in patients with suspected acute coronary syndrome

Associations between socioeconomic status, clinical variables, and non-COVID-19 sepsis risk

Novel AI-powered method detects antimicrobial resistance within 30 minutes

Green tea-silver nanoparticles: A promising weapon against superbugs

Latest surveillance data shows a rise in antibiotic resistant infections and associated deaths

Revolutionizing critical care: the potential of gut microbiota therapeutics

BMI should not be used to determine eligibility for gender-affirming chest surgery

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

Study exposes gaps in pediatric antibiotic effectiveness in Southeast Asia, calls for tailored treatments

Microscopic inflammation in IBD linked to higher risk of serious infections

Study reveals how SARS-CoV-2 alters mitochondria, leading to energy outages and organ failure

Antibiotics no longer effective in treating childhood infections in large parts of the world

$3.4 million grant awarded to identify therapeutic treatments for acute respiratory distress syndrome

How strep bacteria outsmart your immune system and why it matters for treatment

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sepsis News and Research

Latest Sepsis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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