Sepsis News and Research

Latest Sepsis News and Research

New tool can help doctors identify patients at highest risk for respiratory failure after surgery

A new prediction tool can help doctors better identify patients who are at highest risk for respiratory failure after surgery and therefore prevent the often deadly condition, suggest data from a large multi-center study published in the May issue of Anesthesiology.

23 Apr 2014

Study helps physicians better identify patients at risk of acute respiratory distress syndrome

Acute respiratory distress syndrome is a leading cause of respiratory failure after surgery. Patients who develop the lung disorder postoperatively are at higher risk of dying in the hospital, and those who survive the syndrome may still bear its physical effects years later.

22 Apr 2014

Genmab/GSK receive FDA sBLA approval for Arzerra in combination with chlorambucil for treatment of CLL

GlaxoSmithKline plc and Genmab A/S announced today that the U.S. Food and Drug Administration (FDA) has approved a Supplemental Biologic License Application (sBLA) for the use of Arzerra® (ofatumumab), a CD20-directed cytolytic monoclonal antibody, in combination with chlorambucil for the treatment of previously untreated patients with chronic lymphocytic leukaemia (CLL) for whom fludarabine-based therapy is considered inappropriate.

21 Apr 2014

Study suggests that improving newborns' bacterial environment could fend off infections

Mothers give a newborn baby a gift of germs-germs that help to kick-start the infant's immune system. But antibiotics, used to fend off infection, may paradoxically interrupt a newborn's own immune responses, leaving already-vulnerable premature babies more susceptible to dangerous pathogens.

21 Apr 2014

New insight provides potential to improve treatment for sepsis

In a review published in the April issue of Immunity, Kevin J. Tracey, MD, president of The Feinstein Institute for Medical Research, says it's time to take a fresh look at the medical community's approach to treating sepsis, which kills millions worldwide every year, including more than 200,000 Americans.

18 Apr 2014

Isansys awarded two SBRI Healthcare contracts to improve patient monitoring services

Isansys Lifecare Limited, the provider of complete real-time physiological patient status services and systems, today announces that it has won two SBRI (Small Business Research Initiative) Healthcare contracts.

From Isansys Lifecare Ltd. 15 Apr 2014

1/3 of ICU patients develop depression that typically manifests as physical symptoms

A third of intensive care patients develop depression that typically manifests as physical, or somatic, symptoms such as weakness, appetite change, and fatigue, rather than psychological symptoms, according to one of the largest studies to investigate the mental health and functional outcomes of survivors of critical care, published in The Lancet Respiratory Medicine.

7 Apr 2014

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Astellas Pharma Inc. and Medivation Inc. today announced the submission of a variation to amend the European Marketing Authorization Application for XTANDI® (enzalutamide) capsules for the treatment of adult men with metastatic castration-resistant prostate cancer (mCRPC) who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy and in whom chemotherapy is not yet clinically indicated.

4 Apr 2014

Managing pregnancy-related complications: an interview with Dr. Mark Zakowski

Pregnancy-related mortality has increased over the last 25 years. Ten years ago the top three pregnancy-related mortality diagnoses were hemorrhage, preeclampsia, and embolism (includes thrombotic and amniotic).

2 Apr 2014

Fewer blood transfusions reduce infection rates by nearly 20%

Blood transfusions are among the most common treatments for hospitalized patients nationwide, but doing them less often reduces infection rates by nearly 20 percent, according to a study in the Journal of the American Medical Association co-authored by Neil Blumberg, M.D., professor at the University of Rochester School of Medicine and Dentistry.

2 Apr 2014

New biomarker test accurately estimates mortality risk in patients with septicemia

Septic shock is a severe systemic infection and major cause of death for the old and young alike. Unfortunately, researchers say testing new drug regimens to stop the infection is confounded because clinical trials include patients who are either too sick to be saved by experimental therapies or not sick enough to warrant the treatments.

27 Mar 2014

Researchers decode effects of antimicrobial peptide on bacterial cells

The team of Julia Bandow, who heads the RUB's Junior Research Group Microbial Antibiotic Research, has been studying the MP196 peptide as a representative of a group of very small positively charged peptides that consist of some four to ten amino acids.

27 Mar 2014

AM-Pharma reports positive results from recAP Phase I trial for Acute Kidney Injury

AM-Pharma B.V., a biopharmaceutical company focused on the development of recAP (recombinant human Alkaline Phosphatase) for inflammatory indications, announces the results of its Phase I trial with both single and multiple ascending doses, which demonstrate that recAP is safe and well tolerated at all doses.

26 Mar 2014

United Therapeutics' Remodulin Injection gets approval in Japan for PAH treatment

United Therapeutics Corporation today announced that Japan's Ministry of Health, Labour and Welfare has granted approval for Remodulin (treprostinil) Injection for the treatment of pulmonary arterial hypertension (PAH) by subcutaneous and intravenous administration.

26 Mar 2014

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

A University of Cincinnati (UC) trauma and critical care researcher has received a National Institutes of Health grant to better understand how "microparticles" in stored blood can contribute to inflammation and injury after resuscitation from traumatic injury.

25 Mar 2014

Study examines events that lead to sepsis by Streptococcus pneumoniae

An international team of academics, including Professor Marco Oggioni from the University of Leicester's Department of Genetics, has studied how localised infections can turn into the dangerous systematic disease sepsis - and has identified for the first time through genetic evidence that a single bacteria could be the cause.

24 Mar 2014

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

Babies born prematurely are surviving in increasing numbers. But many withstand complications of early birth only to suffer late-onset sepsis - life-threatening bloodstream infections that strike after infants reach 72 hours of age.

20 Mar 2014

Scientists describe gut bacteria that cause sepsis in preterm infants

Researchers studying intestinal bacteria in newborns have characterized the gut bacteria of premature infants who go on to develop sepsis, a serious and potentially life-threatening condition caused by bacteria in the bloodstream.

19 Mar 2014

Study provides evidence that sepsis-related mortality has steadily decreased over time

In critically ill patients in Australia and New Zealand with severe sepsis or septic shock, there was a decrease in the risk of death from 2000 to 2012, findings that were accompanied by changes in the patterns of discharge of intensive care unit (ICU) patients to home, rehabilitation, and other hospitals, according to a study appearing in JAMA.

19 Mar 2014

Cardiac arrest during childbirth may be 2 times more common than previously reported

Although cardiac arrest during childbirth is rare, it may be two times more common than previously reported in the literature, suggests the first large U.S. study on the potentially deadly condition published in the April issue of Anesthesiology.

19 Mar 2014

Sepsis News and Research

Latest Sepsis News and Research

New tool can help doctors identify patients at highest risk for respiratory failure after surgery

Study helps physicians better identify patients at risk of acute respiratory distress syndrome

Genmab/GSK receive FDA sBLA approval for Arzerra in combination with chlorambucil for treatment of CLL

Study suggests that improving newborns' bacterial environment could fend off infections

New insight provides potential to improve treatment for sepsis

Isansys awarded two SBRI Healthcare contracts to improve patient monitoring services

1/3 of ICU patients develop depression that typically manifests as physical symptoms

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Managing pregnancy-related complications: an interview with Dr. Mark Zakowski

Fewer blood transfusions reduce infection rates by nearly 20%

New biomarker test accurately estimates mortality risk in patients with septicemia

Researchers decode effects of antimicrobial peptide on bacterial cells

AM-Pharma reports positive results from recAP Phase I trial for Acute Kidney Injury

United Therapeutics' Remodulin Injection gets approval in Japan for PAH treatment

UC receives grant to better understand how "microparticles" in blood contribute to inflammation, injury

Study examines events that lead to sepsis by Streptococcus pneumoniae

Preterm babies' guts harbor infectious microbes that can cause late-onset sepsis

Scientists describe gut bacteria that cause sepsis in preterm infants

Study provides evidence that sepsis-related mortality has steadily decreased over time

Cardiac arrest during childbirth may be 2 times more common than previously reported

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sepsis News and Research

Latest Sepsis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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