Sepsis News and Research

Latest Sepsis News and Research

Boston researchers develop neonatal mouse model of sepsis

Sepsis, or bacterial infection of the bloodstream, is a grave, hard-to-diagnose threat in premature newborns in the NICU. Even when it's detected and treated with antibiotics, its inflammatory effects can harm fragile babies' development. Now, researchers at Boston Children's Hospital have modeled the effects of sepsis on the unique newborn immune system, using mice.

7 Sep 2012

Hebrew University researcher develops anti-inflammatory and anti-allergic family of drugs

A synthetic, anti-inflammatory and anti-allergic family of drugs to combat a variety of illnesses while avoiding detrimental side effects has been developed by a Hebrew University of Jerusalem researcher.

7 Sep 2012

Postop complications are greatest risk for 30-day readmission

Postoperative complications, particularly gastrointestinal, are the greatest driver behind 30-day hospital readmissions, show study results involving data for over 1000 general surgery patients.

6 Sep 2012

On-the-spot test aids postsurgical coagulopathy management

Point-of-care thromboelastometric and aggregometric testing helps to reduce exposure to allogenic blood products in patients with coagulopathy after cardiac surgery, a randomized trial shows.

5 Sep 2012

Pediatric central line infections reduced by ‘best practice’ guidelines

The number of central line-associated bloodstream infections sustained by hospitalized children with cancer can be substantially reduced by encouraging staff to follow simple “best practice” regulations, say researchers.

4 Sep 2012

High-dose vitamin D appears to help patients with TB recover more quickly

For decades before antibiotics became generally available, sunshine was used to treat tuberculosis, with patients often being sent to Swiss clinics to soak up the sun's healing rays. Now, for the first time scientists have shown how and why heliotherapy might, indeed, have made a difference.

4 Sep 2012

Relocating intensive care nurseries reduces late-onset sepsis rates

Relocating to a newly designed neonatal intensive care nursery significantly reduces severe late-onset sepsis rates in very-preterm and/or very-low-birthweight infants, although it remains relatively common, conclude Australian scientists.

3 Sep 2012

Sophiris announces data from PRX302 transrectal safety study on Benign Prostatic Hyperplasia

Sophiris Bio Inc. today announced data from its transrectal safety study, in which PRX302, the company's drug candidate for the treatment of Benign Prostatic Hyperplasia (BPH or enlarged prostate), was well tolerated through three months following a transrectal injection.

1 Sep 2012

Postoperative complications lead to hospital readmissions among general surgery patients

Postoperative complications are the most significant independent risk factor leading to 30-day hospital readmissions among general surgery patients, according to a new exploratory study published in the September issue of the Journal of the American College of Surgeons.

28 Aug 2012

Blood clotting treatment algorithms help decrease transfusion requirements in cardiac surgery patients

In patients who undergo cardiac surgery, severe perioperative bleeding and its treatment are often associated with increases in major cardiac and non-cardiac adverse events and greater mortality. A study from the September issue of Anesthesiology determined certain blood clotting treatment algorithms helped decrease blood transfusion requirements in cardiac surgery patients and were associated with improved outcomes and hospital cost-savings.

23 Aug 2012

Bile duct cancer chosen as next indication for PCI Biotech

PCI Biotech (PCIB) the Norwegian biopharmaceutical company, reported today that it has chosen bileduct cancer as the next indication for the use of its PCI (photochemical internalisation) localised cancer therapy. In this indication PCI Biotech’s proprietary photosensitiser Amphinex® will be used in combination with the generic cytotoxic agent gemcitabine. The aim is to start the clinical Proof of Concept study within end of 1H 2013.

21 Aug 2012

Talk smoothes the way to better understanding sick babies

Clinicians must foster improved communication with the mothers of critically ill newborns to improve understanding of their child’s condition, research suggests.

20 Aug 2012

Communication problems between clinicians and mothers of critically ill newborns

Research from the Johns Hopkins Children’s Center suggests that common language may also be the divide standing between mothers of critically ill newborns and the clinicians who care for them.

17 Aug 2012

Vancomycin may not always be the best choice for treatment of bloodstream infections

The antibiotic most commonly prescribed to treat bloodstream infections in dialysis patients may not always be the best choice, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

17 Aug 2012

Johns Hopkins undergraduates invent disposable suturing tool

After a surgeon stitches up a patient's abdomen, costly complications -- some life-threatening -- can occur. To cut down on these postoperative problems, Johns Hopkins undergraduates have invented a disposable suturing tool to guide the placement of stitches and guard against the accidental puncture of internal organs.

17 Aug 2012

Special device provides evidence of how bloodstream infections begin

New research may help explain why hundreds of thousands of Americans a year get sick - and tens of thousands die - after bacteria get into their blood. It also suggests why some of those bloodstream infections resist treatment with even the most powerful antibiotics.

16 Aug 2012

U of U researchers receive NIH grant to study cellular and molecular causes of blood clots

University of Utah Department of Medicine researchers have received $16 million from the National Institutes of Health (NIH) to set up a translational research center to study the cellular and molecular causes of blood clots, a serious threat to millions of people who have diabetes, are obese or have other metabolic disorders.

15 Aug 2012

Low platelet count not associated with patent ductus arteriosus

Thrombocytopenia in the first 24 hours after birth is not linked to patent ductus arteriosus in low birthweight infants, research shows.

13 Aug 2012

Clinical trials to test safety of 3K3A-APC in patients with ischemic stroke

Clinical trials start this week for a stroke drug initially created by a team led by scientists at The Scripps Research Institute and the University of Southern California (USC), and further developed by biotech company ZZ Biotech.

9 Aug 2012

Giving antibiotics just before cesarean section prevents infections

Giving antibiotics before cesarean section surgery rather than just after the newborn's umbilical cord is clamped cuts the infection rate at the surgical site in half, according to researchers at Washington University School of Medicine in St. Louis and Barnes-Jewish Hospital.

3 Aug 2012