Serotonin News and Research

Latest Serotonin News and Research

TSRI scientists study 3-D structure of glucagon receptor for treatment of diabetes

The study is reported on July 17, 2013, in an advance online edition of the journal Nature, alongside a British laboratory's structural study of another member of the same class of receptors-known as "class B" G protein-coupled receptors (GPCRs).

18 Jul 2013

USC study shows missing brain protein may be responsible for severe over-worry and fear

A little bit of learned fear is a good thing, keeping us from making risky, stupid decisions or falling over and over again into the same trap. But new research from neuroscientists and molecular biologists at USC shows that a missing brain protein may be the culprit in cases of severe over-worry, where the fear perseveres even when there's nothing of which to be afraid.

16 Jul 2013

Coffee and appetite: an interview with Matt Schubert and Associate Professor Ben Desbrow, Griffith University

We wanted to do something a bit different than the “typical” work on caffeine and exercise, and I have considerable interest in appetite regulation, so we built up from there.

15 Jul 2013

MDPV stimulant effects could be more addictive than methamphetamine, say TSRI researchers

Scientists at The Scripps Research Institute have published one of the first laboratory studies of MDPV, an emerging recreational drug that has been sold as “bath salts.”

11 Jul 2013

Researchers confirm that bath salts could be more addictive than methamphetamine

Scientists at The Scripps Research Institute (TSRI) have published one of the first laboratory studies of MDPV, an emerging recreational drug that has been sold as "bath salts." The TSRI researchers confirmed the drug's powerful stimulant effects in rats and found evidence that it could be more addictive than methamphetamine, one of the most addictive substances to date.

11 Jul 2013

Brisdelle receives FDA approval to treat hot flashes associated with menopause

The U.S. Food and Drug Administration today approved Brisdelle (paroxetine) to treat moderate to severe hot flashes (vasomotor symptoms) associated with menopause. Brisdelle, which contains the selective serotonin reuptake inhibitor paroxetine mesylate, is currently the only non-hormonal treatment for hot flashes approved by the FDA.

29 Jun 2013

Eisai submits BELVIQ NDS with Health Canada

Arena Pharmaceuticals, Inc. announced today that Eisai Limited (based in Mississauga, Ontario), a subsidiary of Eisai Inc., has submitted a New Drug Submission for BELVIQ (lorcaserin HCl) with Health Canada.

26 Jun 2013

Researchers discover a rational source of pain in skin of patients with fibromyalgia

Fibromyalgia, a painful condition affecting approximately 10 million people in the U.S., is not imaginary after all, as some doctors have believed. A discovery, published this month in PAIN MEDICINE (the journal of the American Academy of Pain Medicine), clearly now demonstrates that fibromyalgia may have a rational biological basis located in the skin.

19 Jun 2013

Study shows 1 in 8 patients at risk of developing serious ADE take OTC NSAIDs

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, shows that one in eight patients at risk of developing a serious adverse drug event is taking over-the-counter non-steroidal anti-inflammatory drugs, often to treat a musculoskeletal complaint.

13 Jun 2013

Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

The presence of Lewy bodies in nerve cells, formed by intracellular deposits of the protein α-synuclein, is a characteristic pathologic feature of Parkinson's Disease (PD). In the quest for an animal model of PD that mimics motor and non-motor symptoms of human PD, scientists have developed strains of mice that overexpress α-synuclein.

10 Jun 2013

Common antidepressant medications may impair a form of learning, new report suggests

An interesting new report of animal research published in Biological Psychiatry suggests that common antidepressant medications may impair a form of learning that is important clinically.

10 Jun 2013

Study: Individuals with ASDs show decrease metabolism of amino acid L-tryptophan

Researchers at the JC Self Research Institute of the Greenwood Genetic Center (GGC), along with collaborators from Biolog, Inc. in California, have reported an important discovery in the understanding of autism which was published this week in Molecular Autism.

7 Jun 2013

GLYX-13 drug induces antidepressant results without street drug side effects

GLYX-13, a molecular cousin to ketamine, induces similar antidepressant results without the street drug side effects, reported a study funded by the National Institute of Mental Health (NIMH) that was published last month in Neuropsychopharmacology.

31 May 2013

Long-term depression linked with life-threatening chronic disease, earlier death

The first symptoms of major depression may be behavioral, but the common mental illness is based in biology — and not limited to the brain. In recent years some studies have linked major, long-term depression with life-threatening chronic disease and with earlier death, even after lifestyle risk factors have been taken into account.

23 May 2013

Antidepressant treatment results in lower rate of MSIMI

Among patients with stable coronary heart disease and mental stress-induced myocardial ischemia (MSIMI), 6 weeks of treatment with the antidepressant escitalopram, compared with placebo, resulted in a lower rate of MSIMI, according to a study in the May 22/29 issue of JAMA.

22 May 2013

UTMB researchers awarded grant to study gene therapy techniques to eliminate neuropathic pain

University of Texas Medical Branch at Galveston researchers have been awarded a five-year, $1.8 million grant by the National Institute of Neurological Disorders and Stroke to apply the techniques of gene therapy to the problem of neuropathic pain - that is, pain that arises from a malfunction in the nervous system.

21 May 2013

Patients with treatment-resistant depression benefit from ketamine

Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the Icahn School of Medicine at Mount Sinai.

20 May 2013

Takeda, Lundbeck announce presentation of data from four studies that evaluate vortioxetine for MDD

Takeda Pharmaceutical Company Limited and H. Lundbeck A/S today announced that the companies will be presenting new data from four studies that evaluated effectiveness in treating the overall symptoms of depression in patients taking vortioxetine, an investigational agent under review with the U.S. Food and Drug Administration for the treatment of major depressive disorder.

20 May 2013

Depression and time perception: an interview with Dr Rachel Msetfi, University of Limerick

In clinical terms, depression is defined by the presence of a cluster of symptoms. The Diagnostic Manual used by many psychologists and psychiatrists cites nine symptoms of depression, of which five must be present for a two-week period.

16 May 2013

Findings could help develop new approaches to treat depression and memory loss in the elderly

Scientists have known for some time that exercise induces neurogenesis in a specific brain region, the hippocampus. However, until this study, the underlying mechanism was not fully understood.

14 May 2013

Serotonin News and Research

Latest Serotonin News and Research

TSRI scientists study 3-D structure of glucagon receptor for treatment of diabetes

USC study shows missing brain protein may be responsible for severe over-worry and fear

Coffee and appetite: an interview with Matt Schubert and Associate Professor Ben Desbrow, Griffith University

MDPV stimulant effects could be more addictive than methamphetamine, say TSRI researchers

Researchers confirm that bath salts could be more addictive than methamphetamine

Brisdelle receives FDA approval to treat hot flashes associated with menopause

Eisai submits BELVIQ NDS with Health Canada

Researchers discover a rational source of pain in skin of patients with fibromyalgia

Study shows 1 in 8 patients at risk of developing serious ADE take OTC NSAIDs

Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

Common antidepressant medications may impair a form of learning, new report suggests

Study: Individuals with ASDs show decrease metabolism of amino acid L-tryptophan

GLYX-13 drug induces antidepressant results without street drug side effects

Long-term depression linked with life-threatening chronic disease, earlier death

Antidepressant treatment results in lower rate of MSIMI

UTMB researchers awarded grant to study gene therapy techniques to eliminate neuropathic pain

Patients with treatment-resistant depression benefit from ketamine

Takeda, Lundbeck announce presentation of data from four studies that evaluate vortioxetine for MDD

Depression and time perception: an interview with Dr Rachel Msetfi, University of Limerick

Findings could help develop new approaches to treat depression and memory loss in the elderly

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Serotonin News and Research

Latest Serotonin News and Research

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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