Serotonin News and Research

Latest Serotonin News and Research

PE, CT appear to reduce PTSD symptoms in patients with recent traumatic event

Prolonged exposure therapy, cognitive therapy, and delayed prolonged exposure therapy, appear to reduce posttraumatic stress disorder symptoms in patients who have experienced a recent traumatic event, according to a report published Online First by Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Oct 2011

Novel binding assay can simplify search for potential SERT inhibitors

Many psychiatric conditions are caused by aberrant metabolism of the neurotransmitter serotonin. Researchers in the Department of Pharmacy at LMU have now developed a new screening method, which will facilitate the search for new drugs that modulate the biological activity of serotonin.

1 Oct 2011

Study links pain severity with depression

A new study in The Journal of Pain, published by the American Pain Society, www.ampainsoc.org, shows that changes in pain severity can predict subsequent depression severity and, likewise, a worsening change in depression is an equally strong predictor of subsequent pain severity.

29 Sep 2011

Arena, Eisai announce new data from lorcaserin Phase 3 clinical trial program

Arena Pharmaceuticals, Inc. and Eisai Inc. announced today that new data analyses from the lorcaserin Phase 3 clinical trial program will be presented in poster sessions at Obesity 2011, the 29th Annual Scientific Meeting of The Obesity Society in Orlando, Florida.

27 Sep 2011

Anti-obesity drug Contrave may get another chance to prove itself

With rise obesity around the world there should have been a number of drugs to combat it. The reality is different. There are no safe and effective drugs in the market at present.

22 Sep 2011

Jefferson experts review most commonly used CAM practices for mood disorders

Mood disorders are among the most prevalent mental health issues today. While medication is available, more and more people are turning to complementary and alternative medicine (CAM), including herbal remedies, acupuncture, and meditation to help manage their mood disorders.

22 Sep 2011

Combination of SRIs and cognitive behavior therapy reduces pediatric OCD symptoms

Children and teens with obsessive-compulsive disorder (OCD) who were receiving some benefit from treatment with medication had a significantly greater reduction in OCD symptoms with the addition of cognitive behavior therapy, according to a study in the September 21 issue of JAMA.

21 Sep 2011

Researchers reveal crystal structure of dynamin protein

The crystal structure of the dynamin protein - one of the molecular machines that makes cells work - has been revealed, bringing insights into a class of molecules with a wide influence on health and disease.

19 Sep 2011

U of C researchers create new model of obsessive-compulsive disorder

A new model of obsessive-compulsive disorder (OCD) that mirrors both symptoms of the disease and the timing of its treatment in humans has been created by University of Chicago researchers, according to a new study.

16 Sep 2011

New insight into why some individuals may be more aggressive than others

Fluctuations of serotonin levels in the brain, which often occur when someone hasn't eaten or is stressed, affects brain regions that enable people to regulate anger, new research from the University of Cambridge has shown.

16 Sep 2011

Gene variants that help regulate serotonin may serve as predictor of risk for PSTD symptoms

Data in a study published in the Archives of General Psychiatry suggest that certain variants of a gene that helps regulate serotonin, may serve as a useful predictor of risk for symptoms related to posttraumatic stress disorder (PTSD) following a trauma.

6 Sep 2011

UTHealth to study BMS-820836 in Phase II trial for major depressive disorder

A new medication to treat major depressive disorder in patients who have not responded to other antidepressants is being studied in a Phase II clinical trial by researchers at The University of Texas Health Science Center at Houston.

2 Sep 2011

Health Canada accepts Sunovion Pharmaceuticals Canada's lurasidone NDS for review

Sunovion Pharmaceuticals Canada Inc., formerly Sepracor Pharmaceuticals, Inc., today announced that the New Drug Submission (NDS) for Lurasidone HCl, for the treatment of adult patients with schizophrenia has been accepted for review by Health Canada. The NDS was submitted to Health Canada in June 2011 and will receive a standard review.

24 Aug 2011

Daily exercise can work as well as second antidepressant drug

Exercise can be as effective as a second medication for as many as half of depressed patients whose condition have not been cured by a single antidepressant medication.

24 Aug 2011

Only 20.6% of Medicaid-covered Ohio youths complete full six month antidepressant treatment

About half of Medicaid-covered children and adolescents in Ohio who are in treatment for depression complete their first three months of prescribed antidepressants, and only one-fifth complete the recommended minimum six-month course of drugs to treat depression, new research suggests.

24 Aug 2011

IRSF announces new Rett syndrome translational research awards

The International Rett Syndrome Foundation (IRSF) announced today that it is awarding over $650,000 to support eight cutting-edge projects that aim to accelerate translational research to develop treatments for Rett syndrome.

19 Aug 2011

Mice with enzyme deficiency are unable to properly assess threat

Do you run when you should stay? Are you afraid of all the wrong things? An enzyme deficiency might be to blame, reveals new research in mice by scientists at the University of Southern California.

12 Aug 2011

Women with depression at higher risk of stroke

A new study published this week shows that depression puts middle-aged and older women at significant risk of suffering potentially debilitating strokes.

12 Aug 2011

Research: p38α MAPK protein plays a role in addiction, depression-like behavior

Researchers studying mice are getting closer to understanding how stress affects mood and motivation for drugs.

11 Aug 2011

New research uncovers role of p38alpha in mood disorders, addiction

Stressful experiences increase addictive drug consumption and can precipitate bouts of anxiety or depression in vulnerable people. Although the mechanisms linking stress and human behaviors are not well understood, animal models of some aspects of these behaviors have been developed and have been used to define some of the molecular events that may be responsible for stress vulnerability in people.

11 Aug 2011