Severe Acute Respiratory Syndrome News and Research

Latest Severe Acute Respiratory Syndrome News and Research

J&J vaccine prevents SARS-CoV-2-induced thrombosis and inflammation in hamsters

In a recent study, researchers performed bulk RNA-Seq transcriptomic profiling of lungs from vaccinated and unvaccinated hamsters with the Janssen vaccine.

4 Oct 2021

How durable is the immune response generated from the BNT162b2 vaccine?

In a recent study, researchers analyzed antibody responses to the homologous Wu strain and several other SARS-CoV-2 variants after BNT162b2 vaccination.

4 Oct 2021

mRNA vaccination induces strong humoral immune responses against SARS-CoV-2 in over 80's

A recent study assesses the serological and cellular responses to Pfizer’s BNT162b2 mRNA vaccine in people aged 80-96 years.

4 Oct 2021

Health-related quality of life of COVID-19 patients with long-COVID: Study

Researchers conducted a survey-based study and assessed the impact of long COVID on the health-related quality of life in Japanese COVID-19 patients.

4 Oct 2021

Using nasopharyngeal microbiota as early biomarker in patients with COVID-19

A new study aimed to analyze the nasopharyngeal microbiota of patients who were hospitalized with COVID-19.

4 Oct 2021

Elucidating the natural spillover theory on the SARS-CoV-2 emergence

To determine whether SARS-CoV-2 resulted from a natural spillover into humans, researchers discuss the veracity of early SARS-CoV-2 lineages.

4 Oct 2021

Prevalence of adaptive and prolonged infections’ mutations in receptor-binding domain of SARS-CoV-2 spike protein

A new study used the available nucleotide sequence data on the NCBI COVID-19 database and estimated the global prevalence of adaptive and prolonged infections' mutations in the RBD of the S protein.

4 Oct 2021

Antibody kinetics after natural SARS-CoV-2 infection and COVID-19 vaccination in Hispanic/Latino population

A new study addressing this issue has been published in Viruses that shows that functional neutralizing antibody tests are more relevant indicators than the presence or absence of binding antibodies.

4 Oct 2021

Difficulties of stability and storage of mRNA COVID-19 vaccines

Two researchers have collaborated to review the difficulties faced in storing and transporting these vaccines in a manner that will keep them stable.

4 Oct 2021

Key lessons from COVID-19 pandemic for scientific and clinical communities

In a paper published in the journal Cell, researchers have investigated and criticized clinical care management and drug administration within the pandemic.

4 Oct 2021

Antiviral activity of wheat germ Agglutinin against SARS-CoV-2

A new study reports the antiviral activity of WGA against SARS-CoV-2 and its two Variants of Concern - Alpha and Beta.

4 Oct 2021

Vaccination reduces risk of hospitalization from all SARS-CoV-2 variants

The findings reveal that patients infected with alpha, beta, gamma, and delta variants have a higher risk of hospitalization than those infected with the original viral strain that emerged in Wuhan, China, in late December 2019. The study is currently available on the medRxiv* preprint server while awaiting peer review.

4 Oct 2021

Using a new public antibody to understand SARS-CoV-2 neutralization

SARS-CoV-2 infects host cells by binding to the angiotensin convertase 2 receptor (ACE2) on the cell surface through its trimeric spike (S) protein. SARS-CoV enters host human cells through endosomes, while SARS-CoV-2 enters through the cell surface and endosomes. The present study published in the journal “Cell Reports” aimed to understand the mechanisms of SARS-CoV-2 antibody neutralization to facilitate the development of therapeutic interventions for COVID-19.

4 Oct 2021

REGEN-COV shown to reduce risk of COVID-19–related hospitalization or death from any cause

The phase 1-2 clinical trials conducted using REGEN-COV had shown promising therapeutic benefits in COVID-19 outpatients. Its effect was further investigated in the present phase 3 clinical trial, the findings of which have been published in the "The New England Journal of Medicine".

3 Oct 2021

Machine learning predicts hospital-onset COVID-19 infections using patient contact networks

Researchers from the UK recently developed a real-time machine learning framework that uses dynamic patient contact networks to predict hospital-onset COVID-19 infections (HOCIs) at the patient level. They then tested and validated the framework on international multi-site datasets across various epidemic and endemic periods. This study can be found on the medRxiv* preprint server.

3 Oct 2021

Immune response to SARS-CoV-2 variants of concern after natural infection or vaccination

A recent review paper published in the MDPI's journal Viruses highlights how available vaccines may be effective in protecting individuals against severe forms of coronavirus disease 2019 (COVID-19), but the protection against infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its transmission to others may be reduced – with consequences for community protection and herd immunity.

3 Oct 2021