Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Overabundance of gut bacteria may exacerbate pain in patients with sickle cell disease

An overabundance of the bacteria Veillonella in the digestive tract may increase pain in patients with sickle cell disease (SCD).

8 Nov 2017

Genotype may help identify patients at increased risk for sickle cell disease-related complications

Researchers have found a genotype that could help identify sickle cell disease (SCD) patients at greatest risk of common, yet severe, complications of SCD.

7 Nov 2017

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

A popular drug commonly used to treat Alzheimer's disease has shown promise in laboratory and clinical trials for treating patients with sickle cell disease (SCD).

7 Nov 2017

Mental stress and anticipation of pain may trigger painful sickle cell episodes

Mental stress and the anticipation of pain may cause blood vessels to narrow and trigger episodes of severe pain (vaso-occlusive crisis, or VOC) in sickle cell disease (SCD).

7 Nov 2017

Sickle cell patients suffer discrimination, poor care — and shorter lives

For more than a year, NeDina Brocks-Capla avoided one room in her large, brightly colored San Francisco house — the bathroom on the second floor.

6 Nov 2017

Conference to focus on preventing and reversing consequences of sickle cell disease

Leading experts in the field of sickle cell disease (SCD) research will convene in Washington, D.C., for the Physiological and Pathophysiological Consequences of Sickle Cell Disease conference (November 6–8). The conference, organized by the American Physiological Society, will explore SCD- the world's most prevalent single-gene mutation disease-; and new research on preventing and reversing its deadly consequences.

1 Nov 2017

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

In a recent clinical trial, a gene therapy to treat cerebral adrenoleukodystrophy (CALD) -- a neurodegenerative disease that typically claims young boys' lives within 10 years of diagnosis -- effectively stabilized the disease's progression in 88 percent of patients, researchers from the Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Massachusetts General Hospital report today.

4 Oct 2017

Study suggests frequent blood donation as feasible and safe option for donors

Giving blood more frequently – up to every 8 weeks for men and every 12 weeks for women – has no major side effects and could help to increase blood stocks, according to the first ever randomised trial of blood donation involving more than 45000 people in England published in The Lancet.

25 Sep 2017

Study may contribute to genetic understanding of high-altitude adaptation

Many research groups have recently explored human adaptation and successfully identified candidate genes to high altitude living among three major far-flung global populations: Tibetans, Ethiopians and Peruvians.

22 Sep 2017

New sickle cell disease poll dispels long-held perceptions of African Americans

Pfizer Inc., the National Newspaper Publishers Association, and scholars from Howard University today announced results from a new national poll designed to deepen understanding and gauge perceptions around sickle cell disease (SCD) among African Americans.

21 Sep 2017

New clinical trial begins testing Epigem’s instrument for detection, cure of rare anemias

Epigem today announced that one of its development instruments, MeChem, is being tested in a new clinical trial into the detection and cure of rare anemias. The company has filed two patents relating to the test methods and the associated system.

14 Sep 2017

PCORI Board awards $18 million for two new studies on sickle cell disease

The Patient-Centered Outcomes Research Institute Board of Governors today approved about $18 million to fund two studies comparing different ways to manage the transition of people with sickle cell disease from pediatric to adult care.

13 Sep 2017

Research reveals LEGO-like stacking of protein complexes

When hemoglobin undergoes just one mutation, the protein complexes stick to one another, stacking like LEGO blocks to form long, stiff filaments.

29 Aug 2017

Scientists develop new system to identify and characterize regulatory DNA sequences

Scientists from the Children's Medical Center Research Institute at UT Southwestern have developed an innovative system to identify and characterize the molecular components that control the activities of regulatory DNA sequences in the human genome.

24 Aug 2017

Expert highlights CRISPR’s applications, limitations, and ethical concerns

"Good morning, doctor, I am here for my gene editing appointment." In the future, could this be a greeting heard in physician offices around the world? With the introduction of CRISPR technology, genetic material can now be more easily and precisely edited, even creating changes that can subsequently be inherited by offspring.

1 Aug 2017

Computer models provide new details of how sickle cell disease manifests inside red blood cells

Computer models developed by Brown University mathematicians show new details of what happens inside a red blood cell affected by sickle cell disease.

28 Jul 2017

First in-car study of rush hour pollution finds alarming results

The first in-car measurements of exposure to pollutants that cause oxidative stress during rush hour commutes has turned up potentially alarming results.

21 Jul 2017

Infographic displays facts and information about stem cells, cord blood

Over 40,000 people have successfully stored stem cells with Smart Cells, however the industry is still relatively unknown and often subject to misinformation. In a bid to increase awareness and understanding of stem cell collection at birth, Smart Cells have created an informative infographic.

17 Jul 2017

New program gives free legal help to families for health-related issues

Chicago families with kids who have complicated medical conditions now have easier access to legal help, thanks to a new partnership between the University of Illinois at Chicago and Legal Council for Health Justice.

11 Jul 2017

New treatment receives FDA approval to reduce complications of sickle cell disease

The U.S. Food and Drug Administration today approved Endari (L-glutamine oral powder) for patients age five years and older with sickle cell disease to reduce severe complications associated with the blood disorder.

7 Jul 2017

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Overabundance of gut bacteria may exacerbate pain in patients with sickle cell disease

Genotype may help identify patients at increased risk for sickle cell disease-related complications

Popular Alzheimer's drug shows promise in clinical trials for treating patients with sickle cell disease

Mental stress and anticipation of pain may trigger painful sickle cell episodes

Sickle cell patients suffer discrimination, poor care — and shorter lives

Conference to focus on preventing and reversing consequences of sickle cell disease

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

Study suggests frequent blood donation as feasible and safe option for donors

Study may contribute to genetic understanding of high-altitude adaptation

New sickle cell disease poll dispels long-held perceptions of African Americans

New clinical trial begins testing Epigem’s instrument for detection, cure of rare anemias

PCORI Board awards $18 million for two new studies on sickle cell disease

Research reveals LEGO-like stacking of protein complexes

Scientists develop new system to identify and characterize regulatory DNA sequences

Expert highlights CRISPR’s applications, limitations, and ethical concerns

Computer models provide new details of how sickle cell disease manifests inside red blood cells

First in-car study of rush hour pollution finds alarming results

Infographic displays facts and information about stem cells, cord blood

New program gives free legal help to families for health-related issues

New treatment receives FDA approval to reduce complications of sickle cell disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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