Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

New study finds nitric oxide gas appears to affect source of sickle cell pain crises

Nitric oxide gas appears to directly impact the source of the classic, disabling pain crises of sickle cell disease, Georgia Health Sciences University researchers report.

10 May 2011

Selexys begins patient enrollment in SelG1 Phase I study for sickle cell disease

Selexys Pharmaceuticals announced today that it has initiated enrollment in a Phase I clinical study of its lead compound, SelG1, a humanized anti-P-selectin antibody.

5 May 2011

Frequently hospitalized patients may need a specialist focused on their care: Hospital care expert

Declining rates of hospitalization have discouraged primary care doctors from seeing their patients in the hospital and encouraged the growing use of "hospitalists," a new physician specialty focused on the care of hospitalized patients.

30 Apr 2011

HemaQuest initiates HQK-1001 Phase 2 study in sickle cell disease

HemaQuest Pharmaceuticals, Inc., a biotechnology company focused on developing small molecule therapeutics to treat hemoglobin disorders, announced today that clinical investigators have enrolled the first patient in a randomized multi-dose Phase 2 study of HQK-1001 in patients with sickle cell disease.

26 Apr 2011

Malaria diagnosis made easy with smart phone app

Malaria kills nearly 1 million children a year, mostly in developing countries with little infrastructure and few resources. For the 9th Imagine Cup 2011 - a student contest sponsored by Microsoft, student entrants were asked to “imagine a world where technology helps solve the toughest problems.” Tristan Gibeau 25, a graduate computer engineering student at the University of Central Florida in Orlando and his team developed an ‘app’, LifeLens, to detect malaria.

10 Apr 2011

Pregnancy and pre-pregnancy genetic tests approved for all

According to a government’s advisory body on genetics, genetic tests for conditions that can be passed on to future generations should be more widely available before pregnancy. There are “no specific social, ethical or legal principles” against preconception screening, a Human Genetics Commission report has ruled. It said testing should be available to any couples who may benefit from it. The UK National Screening Committee will now consider the findings.

7 Apr 2011

Texas Children's Hospital and Baylor College of Medicine create Texas Children's Center for Global Health

Texas Children's Hospital and Baylor College of Medicine (BCM) today announced the creation of the Texas Children's Center for Global Health and the appointment of renowned physician-scientist Dr. Russell E. Ware as director.

31 Mar 2011

State laws regarding baby blood samples analyzed

State laws and policies governing the storage and use of surplus blood samples taken from newborns as part of the routine health screening process range from explicit to non-existent, leaving many parents ill-informed about how their babies' left over blood might be used, according to a team led by a member of the Johns Hopkins Berman Institute of Bioethics, in collaboration with researchers from the University of Utah. A report on their analysis of the subject is published March 28 in the journal Pediatrics.

28 Mar 2011

Cortex reports net loss of $0.01 per share for quarter ended December 31, 2010

Cortex Pharmaceuticals, Inc. reported a net loss applicable to common stock of $984,000, or $0.01 per share for the quarter ended December 31, 2010 compared with a net loss of $1,599,000, or $0.02 per share for the corresponding prior year period.

18 Mar 2011

Researchers develop novel system to show how specific mutations can induce glioblastoma

Mutations in three pathways important for suppressing tumors cooperate to launch glioblastoma, an aggressive brain tumor that strikes children and adults. But new research from St. Jude Children's Research Hospital scientists shows those changes alone are not sufficient to cause cancer.

15 Mar 2011

Research: CREBBP mutation may help cancer resist steroid treatment, fuel ALL's return

Despite dramatically improved survival rates for childhood acute lymphoblastic leukemia, relapse remains a leading cause of death from the disease. Work led by St. Jude Children's Research Hospital investigators identified mutations in a gene named CREBBP that may help the cancer resist steroid treatment and fuel ALL's return.

10 Mar 2011

NYBC urges African American, Hispanic descent to donate blood for special patients

A hospitalized single mother from Queens is calling for more African Americans to become blood donors, so that she and many others may be able to live. People may call New York Blood Center at 1-800-933-BLOOD or visit www.nybloodcenter.org for more information about giving blood, and where to donate.

22 Feb 2011

SynthRx to become wholly-owned subsidiary of ADVENTRX

ADVENTRX Pharmaceuticals, Inc. today announced that it has entered into a definitive agreement to acquire SynthRx, Inc., a private biotechnology company developing a purified form of a rheologic and antithrombotic agent, poloxamer 188.

14 Feb 2011

Silent strokes can cause long-term cognitive, learning deficits in children with sickle cell disease

Silent strokes, which have no immediate symptoms but could cause long-term cognitive and learning deficits, occur in a significant number of severely anemic children, especially those with sickle cell disease, according to research presented at the American Stroke Association's International Stroke Conference 2011.

13 Feb 2011

Genomic study identifies link between Native American ancestry, relapse in young leukemia patients

The first genome-wide study to demonstrate an inherited genetic basis for racial and ethnic disparities in cancer survival linked Native American ancestry with an increased risk of relapse in young leukemia patients. The work was done by investigators at St. Jude Children's Research Hospital and the Children's Oncology Group.

6 Feb 2011

New compound appears to prevent pain crises in sickle cell disease: GHSU

A new compound appears to prevent the traffic jam of cells that causes debilitating pain crises and associated mortality in sickle cell disease, Georgia Health Sciences University researchers report.

1 Feb 2011

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

Widespread screening or routine ultrasound for blocked neck arteries to determine stroke risk isn't necessary, according to new guidelines from the American Heart Association/American Stroke Association, American College of Cardiology and other groups.

1 Feb 2011

American Red Cross urges all eligible donors to donate blood

Severe winter weather throughout much of the eastern half of the United States in recent weeks has already caused the cancellation of more than 14,000 blood and platelet donations through the American Red Cross. With more winter weather and a possible coastal storm predicted, the Red Cross is urging all eligible blood donors to help boost its blood supply back up to sufficient levels.

25 Jan 2011

Collaborative study may lead to improved influenza vaccine and vaccines for other respiratory virus infections

A collaborative project between researchers at the Trudeau Institute and their colleagues at St. Jude Children's Research Hospital in Memphis, Tenn., offers new insights that may lead to an improved strategy to protect against the influenza virus and other viruses that infect the respiratory tract.

19 Jan 2011

Study reveals novel role of adenosine signaling in sickle cell disease

Metabolon, Inc., the leader in metabolomics, biomarker discovery and analysis, announces the publication of "Novel Role of Adenosine Signaling in Sickle Cell Disease", in Nature Medicine. Application of non-targeted biochemical profiling (metabolomics) to a mouse model of sickle cell disease (SCD) revealed a detrimental role of adenosine signaling in SCD and suggested novel therapeutic targets. The study was carried out in collaboration with The University of Texas Health Science Center at Houston.

21 Dec 2010

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

New study finds nitric oxide gas appears to affect source of sickle cell pain crises

Selexys begins patient enrollment in SelG1 Phase I study for sickle cell disease

Frequently hospitalized patients may need a specialist focused on their care: Hospital care expert

HemaQuest initiates HQK-1001 Phase 2 study in sickle cell disease

Malaria diagnosis made easy with smart phone app

Pregnancy and pre-pregnancy genetic tests approved for all

Texas Children's Hospital and Baylor College of Medicine create Texas Children's Center for Global Health

State laws regarding baby blood samples analyzed

Cortex reports net loss of $0.01 per share for quarter ended December 31, 2010

Researchers develop novel system to show how specific mutations can induce glioblastoma

Research: CREBBP mutation may help cancer resist steroid treatment, fuel ALL's return

NYBC urges African American, Hispanic descent to donate blood for special patients

SynthRx to become wholly-owned subsidiary of ADVENTRX

Silent strokes can cause long-term cognitive, learning deficits in children with sickle cell disease

Genomic study identifies link between Native American ancestry, relapse in young leukemia patients

New compound appears to prevent pain crises in sickle cell disease: GHSU

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

American Red Cross urges all eligible donors to donate blood

Collaborative study may lead to improved influenza vaccine and vaccines for other respiratory virus infections

Study reveals novel role of adenosine signaling in sickle cell disease

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Sickle Cell Disease News and Research

Latest Sickle Cell Disease News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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