T Cell News and Research

Latest T Cell News and Research

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Children's Hospital Los Angeles has been awarded a $2 million grant from the state of California to study a precision medicine approach to screening children for adverse childhood experiences.

3 Jun 2021

Could a green tea compound combat SARS-CoV-2?

Researchers recently published an article that reviewed the mechanisms by which EGCG could inhibit SARS-CoV-2 infection and the various syndromes caused by COVID-19.

3 Jun 2021

Heterologous AstraZeneca and Pfizer vaccines induce strong immune response and T cell reactivity against multiple SARS-CoV-2 variants

Researchers from Germany recently analyzed a cohort of 26 individuals in the age range of 25 to 46 (median 30.5) years who had received a ChAdOx1 nCoV-19 prime vaccine followed by a BNT162b2 boost vaccine after a 56-day interval due to changing vaccine recommendations in Germany. There were 16 females and 10 males in the cohort, and they were assessed for immune responses, reactogenicity, and T cell reactivity. This study is published on the medRxiv* preprint server.

3 Jun 2021

Antibody treatment reactivates the immune defense in patients with advanced-stage cancer

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer.

3 Jun 2021

Scientists identify many existing drugs with antiviral activity against coronavirus

Mining the world's most comprehensive drug repurposing collection for COVID-19 therapies, scientists have identified 90 existing drugs or drug candidates with antiviral activity against the coronavirus that's driving the ongoing global pandemic.

3 Jun 2021

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Type 2 diabetes patients who are not overweight and who have had the disorder for less than a decade can benefit from stromal stem cells transplanted from their own bone marrow, according to a study published today in STEM CELLS Translational Medicine.

3 Jun 2021

Researchers develop rapid antibody screening method for novel COVID-19 therapeutics development

New research undertaken by researchers in the USA describes two parallel but distinct in vivo approaches for the accelerated discovery of antibodies targeting SARS-CoV-2 spike protein.

3 Jun 2021

Known pharmaceutical compounds could provide new therapies for COVID-19

After screening over 12,000 existing treatments, researchers have found many promising antiviral compounds that could treat COVID-19.

3 Jun 2021

Study shows how the physical nature of genome changes before and after cell differentiation

The organization of the human genome relies on physics of different states of matter - such as liquid and solid - a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes as cells transform to serve specific functions, point to new ways to potentially better understand disease and to create improved therapies for cancer and genetic disorders.

3 Jun 2021

Cdkn1a transcript variant 2 is selectively elevated during natural aging across mouse tissues

Aging published "Cdkn1a transcript variant 2 is a marker of aging and cellular senescence" which reported that cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16Ink4a and p21Cip1/Waf1.

3 Jun 2021

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

Oncotarget published "Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations" which reported that unlike lung adenocarcinoma patients, there is no FDA-approved targeted-therapy likely to benefit lung squamous cell carcinoma patients.

3 Jun 2021

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

Oncotarget published "A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV+ head and neck squamous cell carcinomas" which reported that the incidence of human papillomavirus-positive head and neck squamous cell carcinoma has increased dramatically over the past decades due to an increase in infection of the oral mucosa by HPV.

3 Jun 2021

Single mutation to bat virus spike protein allows cell entry using human ACE2

In a paper recently uploaded to the preprint server bioRxiv by Kirchhoff et al. (May 31st, 2021) it is demonstrated that a single mutation to the RaTG13 spike protein results in significantly greater affinity towards the human receptor, indicating that the presence of a positively charged amino group at this position better facilitates interaction with the human ACE2 receptor, and helping to identify other viruses with zoonotic potential.

3 Jun 2021

Epigenetic regulation affects the 3D structure of genome

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

3 Jun 2021

Experts offer plausible solutions to mitigate zoonotic risk associated with intensive animal agriculture

As early as the Neolithic period (circa 3900 BC), the domestication of animals likely led to the development of diseases including measles and smallpox. Since then, zoonotic disease has led to other major transnational outbreaks including HIV, Ebola, SARS, MERS, and H1N1 swine flu, among others.

3 Jun 2021

New research sheds light on the origins of synovial sarcoma

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

3 Jun 2021

Tiny implant reverses diabetes in mice without requiring drugs

A team of researchers led by diabetes specialists and biomedical engineers at Washington University School of Medicine in St. Louis and Cornell University has demonstrated that, using a miniscule device, they can implant insulin-secreting cells into diabetic mice.

3 Jun 2021

T Cell News and Research

Latest T Cell News and Research

Study aims to improve early screening for adverse childhood experiences by using precision medicine

Could a green tea compound combat SARS-CoV-2?

Heterologous AstraZeneca and Pfizer vaccines induce strong immune response and T cell reactivity against multiple SARS-CoV-2 variants

Antibody treatment reactivates the immune defense in patients with advanced-stage cancer

Scientists identify many existing drugs with antiviral activity against coronavirus

Study: Some Type 2 diabetes patients can benefit from bone marrow stem cell transplants

Researchers develop rapid antibody screening method for novel COVID-19 therapeutics development

Known pharmaceutical compounds could provide new therapies for COVID-19

Study shows how the physical nature of genome changes before and after cell differentiation

Cdkn1a transcript variant 2 is selectively elevated during natural aging across mouse tissues

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

E6-specific inhibitors offer a unique, strategic approach for treating HPV-HNSCC

Single mutation to bat virus spike protein allows cell entry using human ACE2

Epigenetic regulation affects the 3D structure of genome

Experts offer plausible solutions to mitigate zoonotic risk associated with intensive animal agriculture

New research sheds light on the origins of synovial sarcoma

Tiny implant reverses diabetes in mice without requiring drugs

Nanopore sequencing contradicts human genome integration of SARS-CoV-2

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

Long COVID patients at higher risk of small airway disease

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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