T Cell News and Research

Latest T Cell News and Research

New project aims to study the combination of two therapies for pediatric brain cancer

Natasha Sheybani, assistant professor of biomedical engineering at the University of Virginia School of Engineering, will collaborate with researchers at Children's National Hospital to study the combination of two therapies for pediatric brain cancer.

19 Aug 2024

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia (T-ALL), an aggressive and high-risk form of cancer, to one frequently driven by genetic changes in non-coding portions of our DNA.

14 Aug 2024

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

University Hospitals (UH) Seidman Cancer Center hematologist-oncologist Leland Metheny, MD, is leading the trial.

14 Aug 2024

Exploring the distinct characteristics of Nodular Lymphocyte Predominant Hodgkin Lymphoma

This review offers an in-depth exploration of Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL), highlighting its distinct characteristics across various domains such as epidemiology, clinical presentation, histopathology, immunophenotype, genetic findings, and challenges in differential diagnosis.

13 Aug 2024

EZH2's role in cancer progression and therapy explored

Enhancer of zeste homolog 2 (EZH2) is a catalytic subunit of the Polycomb-repressive complex 2 (PRC2), which plays a crucial role in transcriptional repression through the methylation of histone H3 on lysine 27 (H3K27me3).

9 Aug 2024

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

A new research paper was published in Oncotarget's Volume 15 on August 5, 2024, entitled, "Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival."

8 Aug 2024

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

For decades, researchers have worked to develop therapies that can prime the immune system to recognize and attack proteins on the surface of tumor cells.

8 Aug 2024

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

Study reveals a mechanism behind multisystem inflammatory syndrome in children (MIS-C).

7 Aug 2024

The real cost of processed foods: How Western diets are harming global health

A recent study in Nature Medicine reviews the adverse effects of Western diets on human health, highlighting increased risks of chronic diseases and gut dysbiosis. Researchers call for global awareness and promotion of healthier dietary patterns.

6 Aug 2024

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

Chimeric antigen receptor (CAR) T–cell immunotherapy re-engineers a patient's immune cells to target cancer cells.

5 Aug 2024

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

On June 14, 2024, the U.S. FDA approved AstraZeneca's Durvalumab (IMFINZI®) for primary advanced or recurrent endometrial cancer with mismatch repair deficiency. Endometrial cancer is the most prevalent gynecologic cancer, with an estimated 66,200 new U.S. cases in 2023.

From Sino Biological Inc. 5 Aug 2024

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

A study uncovers the presence and activity of immune cells in glioblastoma, revealing new insights into brain tumor immunology and potential treatment avenues.

4 Aug 2024

New AI test may help bowel cancer patients avoid unnecessary chemotherapy

A new artificial intelligence (AI) test to determine the risk of bowel cancers coming back could help patients avoid chemotherapy, according to new research led by the University of Leeds.

31 Jul 2024

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

Neurodivergent traits in childhood double the risk of chronic disabling fatigue by age 18, with inflammation playing a significant mediating role. This highlights the importance of addressing inflammatory markers in managing the health of neurodivergent individuals.

31 Jul 2024

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

The University of Texas MD Anderson Cancer Center and collaborators are initiating a research project that will send T cells to the International Space Station (ISS) to study the effects of prolonged microgravity on cell differentiation, activation, memory and exhaustion.

31 Jul 2024

Can diet alter your biological age?

Research shows that healthy diets lower epigenetic age while added sugar accelerates aging in midlife Black and White women.

31 Jul 2024

ACE technology enhances single-cell protein detection with advanced signal amplification

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize different types of immune cells in research studies and in blood samples from human individuals.

30 Jul 2024

Loss of Gα13 in B-cells linked to increased lymphoma risk due to dietary glutamine

Researchers find that the deletion of Gα13 in B-cells increases lymphoma risk by enhancing proliferation in gut-associated lymph nodes. Dietary glutamine significantly promotes these effects, highlighting a crucial link between diet and cancer.

29 Jul 2024

Overcoming cancer relapse with CAR-Enhancer therapy

Even as they have revolutionized the treatment of certain forms of cancer, CAR T-cell therapies have been shadowed by a significant limitation: many patients, including those whose cancer goes into full remission, eventually relapse. In a new study, Dana-Farber Cancer Institute researchers report on a technique with the potential to eliminate that problem.

29 Jul 2024

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

Allogeneic hematopoietic cell transplantation (HCT) is a commonly used curative therapy for individuals with inborn errors of immunity (IEI).

28 Jul 2024

T Cell News and Research

Latest T Cell News and Research

New project aims to study the combination of two therapies for pediatric brain cancer

Study reveals a paradigm shift in the understanding of T-lineage acute lymphoblastic leukemia

New trial explores BAFF CAR T-cell therapy for relapsed myeloma

Exploring the distinct characteristics of Nodular Lymphocyte Predominant Hodgkin Lymphoma

EZH2's role in cancer progression and therapy explored

Study links renalase-1 and T-cell receptor interaction to increased melanoma survival

Individualized neoantigen cancer therapy demonstrates safety and efficacy in early trials

Research reveals autoimmune mechanism behind multisystem inflammatory syndrome in children

The real cost of processed foods: How Western diets are harming global health

Enhanced CAR T-cell homing boosts treatment efficacy for osteosarcoma

FDA accepted PD-L1 inhibitor durvalumab for the treatment of endometrial cancer

Active immune cells discovered in brain's cranial bone marrow fighting glioblastomas

New AI test may help bowel cancer patients avoid unnecessary chemotherapy

Neurodivergent children face higher risk of chronic disabling fatigue by 18, study finds

MD Anderson and collaborators initiate space project to explore T cell behavior in microgravity

Can diet alter your biological age?

ACE technology enhances single-cell protein detection with advanced signal amplification

Loss of Gα13 in B-cells linked to increased lymphoma risk due to dietary glutamine

Overcoming cancer relapse with CAR-Enhancer therapy

Exploring alemtuzumab in reduced-toxicity conditioning for Asian patients with inborn errors of immunity

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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