Toxicology News and Research

Latest Toxicology News and Research

Genta announces initial trial results for novel drug for bone disease

Genta Incorporated has announced the release of final results from the Company's Phase 1 clinical trial of G4544, a proprietary small molecule that is intended as a treatment for diseases associated with accelerated bone loss. Results showed that the drug was very well-tolerated, and that blood levels were achieved in a range that is known to be clinically bioactive. The data were featured in a poster session at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago on Saturday, May 31, 2008.

2 Jun 2008

Gulf Coast area children who lived in trailer units at risk for long-term illnesses

Tens of thousands of Gulf Coast area children who lived in trailer units provided by the Federal Emergency Management Agency after Hurricane Katrina in 2005 might have increased risk for long-term health problems, according to physicians and federal health officials, the AP/Denver Post reports.

28 May 2008

U.S. patent office grants re-examination of RNA splicing microarray patent on behalf of Jivan

Jivan Biologics, Inc. announced today that the United States Patent and Trademark Office has ordered the re-examination of U.S. Patent No. 6,881,571. The serial number for the reexamination is 90/009,017.

19 May 2008

Risk of Bisphenol A in plastic products, Q & A's

Bisphenol A, an estrogenlike compound in polycarbonate plastics and epoxy resin, has been popping up in the news a lot lately.

30 Apr 2008

Lorus initiates development program exploring novel route of administration for LOR-2040

Lorus Therapeutics Inc. today announced the start of a development program aimed at expanding the therapeutic application of its lead clinical-stage drug LOR-2040 for the treatment of superficial bladder cancer.

22 Apr 2008

Warning about chemical found in plastic bottles and food containers

A chemical used to make plastic bottles and other food containers, is suspected to be linked to hormonal and neurological problems.

17 Apr 2008

New decontamination agent

A new decontamination agent devised by US chemists can deactivate toxic chemicals such as nerve agents and pesticides - leaving only non-toxic, easily disposable by-products, according to research in the New Journal of Chemistry.

8 Apr 2008

What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?

Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.

19 Mar 2008

Artificial butter chemical acetyl harmful to lungs

A new study shows that exposure to a chemical called diacetyl, a component of artificial butter flavoring, can be harmful to the nose and airways of mice.

14 Mar 2008

Scientists unlock secrets of E coli contamination

Using new genetic techniques, scientists are unlocking the secrets of how E coli bacteria contaminate food and make people sick.

11 Mar 2008

Just one hour of exposure to diesel exhaust fumes induces a stress response in brain

If the smell of diesel exhaust isn't enough to make you avoid getting a lungful, new research now shows that even a short exposure to the fumes can affect your brain.

11 Mar 2008

Nanoparticulate matter from exhaust fumes alter the way the brain functions

Dutch researchers say exhaust fumes may give you more than a headache, they could in fact alter the way the brain functions.

11 Mar 2008

Jivan Biologics awarded US patent for splice array analysis

Jivan Biologics Inc., a privately held corporation located in Berkeley, CA, has been awarded US Patent #7,340,349, "Method and System for Identifying Splice Variants of a Gene."

10 Mar 2008

Springer launches 18,000 searchable online protocols in life sciences and biomedicine

Springer Science+Business Media (www.springer.com) has announced the release of Springer Protocols, a protocol database of more than 18,000 searchable online protocols in life sciences and biomedicine.

28 Feb 2008

Protein that stimulates blood vessel growth worsens ovarian cancer

A protein that stimulates blood vessel growth worsens ovarian cancer, but its production can be stifled by a tiny bit of RNA wrapped in a fatty nanoparticle, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute.

27 Feb 2008

Hair loss breakthrough

A healthy individual loses around a hundred hairs a day. Nothing to worry about as long as they are constantly replaced and the losses occur evenly around the whole scalp.

26 Feb 2008

NIH and EPA announce new chemical toxicity testing agreement

Testing the safety of chemicals ranging from pesticides to household cleaners will benefit from new technologies and a plan for collaboration, according to federal scientists from the National Institutes of Health (NIH) and the U.S. Environmental Protection Agency (EPA), who today announced a new toxicity testing agreement.

17 Feb 2008

New understanding of cancer initiation

Researchers at the University of Nebraska Medical Center (UNMC) in Omaha have assisted in a significant discovery - the understanding of a common mechanism of cancer initiation - that could result in better cancer assessment, prevention and detection.

7 Feb 2008

A loss in DNS repair function causes acute myeloid leukemia relapse

A University of Kentucky research team reports that loss of an important DNA repair function, called DNA mismatch repair (MMR), is responsible for refractory/relapsed Acute Myeloid Leukemia (AML).

4 Feb 2008

Leukemia relapse stems from DNA repair function loss

A University of Kentucky research team reports that loss of an important DNA repair function, called DNA mismatch repair (MMR), is responsible for refractory/relapsed Acute Myeloid Leukemia (AML).

30 Jan 2008