Toxicology News and Research

Latest Toxicology News and Research

Arius begins toxicology program for lead anti-cancer antibody

ARIUS Research Inc has announced that the Company has initiated the first study in the formal pre-clinical toxicology program for its lead anti-CD44 drug candidate, which is under development for the treatment of breast, prostate and liver cancers.

23 Jul 2007

Protein IKKa protects checkpoint gene from chemical shutdown

A protein that is largely absent in one type of skin cancer protects an important gene in a cell's defense against harmful mutations from being silenced, researchers at The University of Texas M. D. Anderson Cancer Center report in the July 20 edition of Molecular Cell.

20 Jul 2007

New genomics-based technology

Bruce S. Gillis, M.D., M.P.H., a medical toxicologist and CEO of the research group, The Cytokine Institute, will present a tutorial on a new genomics-based technology, msds1(TM).

16 Jul 2007

$2.5 million for study on how insecticides affect human health

The National Institute of Environmental Health Sciences (NIEHS) has awarded Cornell insecticide toxicologist David Soderlund two grants, providing more than $2.5 million over five years, to study how insecticides affect human health.

4 Jul 2007

Alternative to blood test to detect drugs in the body

The presence of narcotic substances in a person’s body can usually be detected by a blood or urine test.

23 Jun 2007

Men who smoke risk genetic damage to their sperm which is passed on to their children

According to Canadian researchers children could inherit genetic damage from a father who smokes.

3 Jun 2007

Smoking can cause changes in the DNA sequence of sperm cells

The science has long been clear that smoking causes cancer, but new research shows that children could inherit genetic damage from a father who smokes.

3 Jun 2007

Apple peel shows anti-cancer potential

An apple a day keeps the doctor away, Or, what appears to be more accurate: An apple peel a day might help keep cancer at bay, according to a new Cornell study.

3 Jun 2007

Mercury's link to heart disease

Heavy metals and other toxins have been linked to many human diseases, but determining exactly how they damage the body remains a mystery in many cases.

1 Jun 2007

Natalizumab returns to market

Just months after receiving FDA approval, natalizumab, a medication for the treatment of multiple sclerosis (MS) and other inflammatory disorders, was voluntarily withdrawn by its manufacturers after three patients developed a brain infection known as Progressive Multifocal Leukoencephalopathy (PML).

28 May 2007

Imported Chinese seafood not 100% safe

Adding to China's recent problems of food safety is now seafood contamination.

17 May 2007

Pycnogenol natural pine bark extract reduces heart failure

A study to be published in an upcoming edition of the journal of Cardiovascular Toxicology reveals Pycnogenol natural pine bark extract from the French maritime pine tree, helps prevent damage that high blood pressure causes to the heart.

17 May 2007

Chromium 6 in drinking water may cause cancer

Researchers announced today that there is strong evidence a chemical referred to as hexavalent chromium, or chromium 6, causes cancer in laboratory animals when it is consumed in drinking water.

17 May 2007

Discovery may lead to new treatments for lung cancer and blood cancer

The research team uses a genetically modified mouse that produces a muted and constantly active CAAX protein. This is a new model for an extremely aggressive lung cancer and a mild form of blood cancer. In these mice, the production of an enzyme called GGTas1 can also be stopped.

8 May 2007

Prenatal toxicity linked to immune dysfunctions in later life

A Cornell researcher and his wife have conducted the first comprehensive review of later-life diseases that develop in people who were exposed to environmental toxins or drugs either in the womb or as infants.

4 May 2007

Moderate coffee drinking reduces many risks

Although the American Society for Nutrition's popular ,controversy session, at Experimental Biology 2007 focuses on the health effects of coffee drinking, panel chair Dr. James Coughlin, a toxicology/safety consultant at Coughlin & Associates, says that recent advances in epidemiologic and experimental knowledge have transformed many of the negative health myths about coffee drinking into validated health benefits.

1 May 2007

Benzylpiperazine a 'new drug of abuse'

Professor Alison Jones said benzylpiperazine was a ,new drug of abuse, which could have serious clinical effects - similar to those of ecstasy to which it is structurally related.

30 Apr 2007

Babies are exposed to perfluorooctane sulfonate and perfluorooctanoate in the womb

An analysis of nearly 300 umbilical cord blood samples led by researchers at the Johns Hopkins Bloomberg School of Public Health shows that newborn babies are exposed to perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) while in the womb.

25 Apr 2007

Non-coplanar PCBs and related chemicals warrant serious attention for health reasons

Scientists have determined that a specific class of PCB causes significant developmental abnormalities in rat pups whose mothers were exposed to the toxicant in their food during pregnancy and during the early weeks when the pups were nursing.

24 Apr 2007

M. D. Anderson wins $8.3-million to research environmental causes of major diseases

An $8.3-million federal grant to The University of Texas M. D. Anderson Cancer Center Science Park - Research Division addresses the complex interplay between such varied factors as genetics, diet, and environmental exposure to toxins that cause cancer, asthma, diabetes, cardiovascular and other diseases.

21 Apr 2007