Toxicology News and Research

Latest Toxicology News and Research

Novel community-produced biological network models hold potential in drug discovery and toxicology

A new set of community-produced biological network models has been shown to allow a deeper understanding of the mechanisms underlying a range of diseases.

26 Jul 2016

Predictive power of computational toxicology demonstrated with crowd-sources scientific challenge

Results of the Systems Toxicology Computational Challenge have demonstrated how transcriptomics information present in the blood can be used to predict whether people have been exposed or not exposed to specific toxicants.

22 Jul 2016

New multicomponent reactions to develop active compounds against sleeping sickness

Multicomponent reactions are protocols that ease the chemical synthesis of new compounds, and are particularly important to gain molecules with biological activity as therapeutic agents against several pathogens.

13 Jul 2016

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

With more than 7.5 million new cases of Alzheimer’s disease a year, the race to find a vaccine and effective treatment for dementia is growing by the day.

12 Jul 2016

Hops extract activates chemical pathway in cells to help prevent breast cancer

An enriched hops extract activates a chemical pathway in cells that could help prevent breast cancer, according to new laboratory findings from the UIC/NIH Center for Botanical Dietary Supplements Research at the University of Illinois at Chicago.

12 Jul 2016

Food additive tBHQ may be linked to increase in food allergies

A Michigan State University researcher has found that a common food additive may be linked to a rise in food allergies.

11 Jul 2016

Prenatal butylparaben exposure causes various endocrine disrupting effects in rats

Research suggests that butylparaben - which is used in cosmetics and skin care products such as sunscreen - have more endocrine disrupting effects than previously thought.

7 Jul 2016

Buck researchers find new way for possible treatment of AMD

Buck researchers boosted the potency of a broccoli-related compound by ten times and identified it as a possible treatment for age-related macular degeneration (AMD), the leading cause of vision loss affecting more than 10 million older Americans.

7 Jul 2016

WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

The Walter Reed Army Institute of Research announces a Cooperative Research and Development Agreement for the development of a Zika vaccine candidate with Sanofi Pasteur, the vaccines division of Sanofi.

7 Jul 2016

Environmental toxins affect children's brain development, experts agree

An unprecedented alliance of leading scientists, health professionals, and children's and environmental health advocates agree for the first time that today's scientific evidence supports a link between exposures to toxic chemicals in air, water, food and everyday products and children's risks for neurodevelopmental disorders.

4 Jul 2016

KIT researchers develop 3D prostate model based on cryogels

A team of researchers led by Dr. Friederike J. Gruhl and Professor Andrew C. B. Cato at Karlsruhe Institute of Technology are developing a three-dimensional model for prostate cancer research based on cryogels.

25 Jun 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

There is merit in looking at the use of wearable biosensors to detect whether opioid users stay focused on their rehabilitation programs.

23 Jun 2016

Metal ions released by implant wear can damage progenitors of bone-forming cells

In metal-on-metal pairings, both the shell and head of an implant consist of a cobalt-chromium-molybdenum alloy. The release of metal ions into the body has been reported as a result of implant wear. Bone loss (osteolysis) was observed in many cases.

22 Jun 2016

Hops show promise in reducing breast cancer risk

Hops, the flower cones used in beer-making, are also found in dietary supplements designed to help treat post-menopausal symptoms and other conditions. Scientists are now investigating whether an extract from the plant could also help fend off breast cancer.

22 Jun 2016

Highly efficient bacterial agent could improve treatment of Wilson disease

In the 'Journal of Clinical Investigation', scientists at the Helmholtz Zentrum München describe a small peptide that very efficiently binds excess copper from liver cells. This molecule comes from a bacterium's bag of tricks and could be suitable for treating Wilson disease.

21 Jun 2016

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation.

21 Jun 2016

Scientists study fundamentals of tumour surveillance by immune system in mice models

The body's defences detect and eliminate not only pathogens but also tumour cells. Natural killer cells (NK-Cells) are specifically activated by chemical messengers, the Cytokines, to seek and destroy tumour cells.

20 Jun 2016

Endocrine Society members advocate science-based policies to address danger of EDCs

To protect human health, Endocrine Society members called on the European Commission to adopt science-based policies for regulating endocrine-disrupting chemicals in an opinion piece published today in The Lancet Diabetes & Endocrinology.

14 Jun 2016

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

As individuals and as populations our risks of getting diseases are determined partly genetically and partly from the environment that we live in. An important part of that environment that mediates between the outside world and the inside world of our bodies is the microbiome.

10 Jun 2016

Toxicology News and Research

Latest Toxicology News and Research

Novel community-produced biological network models hold potential in drug discovery and toxicology

Predictive power of computational toxicology demonstrated with crowd-sources scientific challenge

New multicomponent reactions to develop active compounds against sleeping sickness

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

Hops extract activates chemical pathway in cells to help prevent breast cancer

Food additive tBHQ may be linked to increase in food allergies

Prenatal butylparaben exposure causes various endocrine disrupting effects in rats

Buck researchers find new way for possible treatment of AMD

WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

Environmental toxins affect children's brain development, experts agree

KIT researchers develop 3D prostate model based on cryogels

Mutant fruit flies provide insight into origins of Parkinson's disease

Researchers use wristband sensors to detect how opioid users in emergency room reacted to dosages

Metal ions released by implant wear can damage progenitors of bone-forming cells

Hops show promise in reducing breast cancer risk

Highly efficient bacterial agent could improve treatment of Wilson disease

E-cigarette use modifies gene expression important for upper airway immune defense

Scientists study fundamentals of tumour surveillance by immune system in mice models

Endocrine Society members advocate science-based policies to address danger of EDCs

Tackling Healthcare Challenges in a Changing World: an Interview with Professor Jeremy Nicholson

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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