Toxicology News and Research

Latest Toxicology News and Research

Drugs approved for various conditions also have antibiotic properties

A number of drugs already approved to treat parasitic infections, cancers, infertility and other conditions also show promise as antibiotic agents against staph and tuberculosis infections, according to a new study by University of Illinois chemists and collaborators. Because these agents act against multiple targets within the bacteria, it may be harder for bacteria to develop resistance.

23 Dec 2015

New article explores harmful algal blooms and their impact on public health, environment

Harmful algal blooms (HABs) occur naturally, but their outbreaks are influenced by climate change and droughts, nutrient enrichment and manmade factors, such as contaminants from sewage and stormwater discharge, natural resource extraction or agricultural runoff, to name a few.

23 Dec 2015

Recreational drug and alcohol use can increase risk of poisoning-related hospital admissions

Poisonings from recreational drug and alcohol use account for 9 percent of all poisoning-related hospital admissions, says a new University of Sydney study revealing that males and people under 30 are at greatest risk.

17 Dec 2015

Many gene variants affect person's response to medication

In recent decades much hope was based on the development of personalised drug treatments, in which genetic tests determine the choice and optimal dose of medication for each individual patient. However, the real breakthrough is still to be seen, and now researchers at Karolinska Institutet show in two separate scientific papers that many more gene variants affect how a person responds to medication than previously thought - and thus that today's analytical tools are too coarse.

16 Dec 2015

Bile acid may help treat fatty liver disease and obesity

A bile acid that can turn off a receptor in the gut has prevented and reversed fatty liver disease in mice, according to an international team of researchers. The compound may help treat certain metabolic disorders, such as Type 2 diabetes and obesity, as well.

16 Dec 2015

VCU Massey Cancer Center scientists reveal signaling process that leads to excessive growth of cancer

The gene p53 has been described as the "guardian of the genome" due to its prominent role in preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function, and now a recent study by VCU Massey Cancer Center scientist Richard Moran, Ph.D., explains why.

15 Dec 2015

Palatin achieves patient enrollment target in pivotal phase 3 studies of bremelanotide for FSD treatment

Palatin Technologies, Inc., a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical needs and commercial potential, today announced it has achieved its patient enrollment target in its two pivotal phase 3 clinical studies of bremelanotide for the treatment of female sexual dysfunction (FSD).

10 Dec 2015

Researchers evaluate contaminants in community garden soils in New York City

While community gardens provide benefits including urban green space, opportunities for recreation, art expression, social gathering, and improved diets, urban gardening may also increase the opportunity for exposure to common urban soil contaminants such as polycyclic aromatic hydrocarbons (PAHs).

8 Dec 2015

Researchers reveal new technique to grow human hepatocytes in the laboratory

In new research appearing in the prestigious journal Nature Biotechnology, an international research team led by The Hebrew University of Jerusalem describes a new technique for growing human hepatocytes in the laboratory. This groundbreaking development could help advance a variety of liver-related research and applications, from studying drug toxicity to creating bio-artificial liver support for patients awaiting transplantations.

27 Nov 2015

New test can detect drug abuse faster

A new test for club drugs like ketamine can detect low levels of drugs in urine and plasma, making it faster, easier and cheaper to identify them. The authors of the study, published in Journal of Chromatography B, say it could give authorities the boost they need to keep up with trends drug (ab)use.

26 Nov 2015

Scientists show evidence for exchange of lactate between different brain cells

Nerve cells cover their high energy demand with glucose and lactate. Scientists of the University of Zurich now provide new support for this. They show for the first time in the intact mouse brain evidence for an exchange of lactate between different brain cells. With this study they were able to confirm a 20-year old hypothesis.

25 Nov 2015

Role of biomarkers in drug development and regulatory decision making

Biomarkers in Medicine, a leading MEDLINE-indexed journal, has published a special focus issue exploring the increasingly important role of biomarkers in both drug development and regulatory decision making.

19 Nov 2015

Lead exposure in early childhood increases risk for sleep problems in later childhood

A new research study from the University of Pennsylvania School of Nursing shows that lead exposure in early childhood are associated with increased risk for sleep problems and excessive daytime sleepiness in later childhood.

13 Nov 2015

New computational method helps predict adverse drug reaction better than traditional computing methods

A new integrated computational method helps predicting adverse drug reaction--which are often lethal--more reliably than with traditional computing methods. This improved ability to foresee the possible adverse effects of drugs may entail saving many lives in the future.

4 Nov 2015

Pittcon will exhibit at the Bioconference clinical diagnostics and research virtual conference

Pittcon is pleased to announce its participation in the “Clinical Diagnostics & Research” virtual conference from November 11 to 12, 2015. Clinicians, researchers, medical experts, and professionals from around the world convene for this free web-conference to learn and interact with a community of like-minded colleagues.

From Pittcon 27 Oct 2015

Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Estrogen-mimicking chemicals called parabens, which are commonly found in an array of personal care products, may be more dangerous at lower doses than previously thought, according to a new study.

27 Oct 2015

Orange pigment may have potential as anti-cancer drug

An orange pigment found in lichens and rhubarb called parietin may have potential as an anti-cancer drug, scientists at Winship Cancer Institute of Emory University have discovered.

20 Oct 2015

Nanodiamonds may improve outcomes for patients undergoing root canals

People undergoing root canals may have gained a powerful, if tiny, new ally. Researchers from the UCLA School of Dentistry have found that using nanodiamonds to fortify a material used in the procedure could significantly improve outcomes for patients.

19 Oct 2015

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

Toxicology News and Research

Latest Toxicology News and Research

Drugs approved for various conditions also have antibiotic properties

New article explores harmful algal blooms and their impact on public health, environment

Recreational drug and alcohol use can increase risk of poisoning-related hospital admissions

Many gene variants affect person's response to medication

Bile acid may help treat fatty liver disease and obesity

VCU Massey Cancer Center scientists reveal signaling process that leads to excessive growth of cancer

Palatin achieves patient enrollment target in pivotal phase 3 studies of bremelanotide for FSD treatment

Researchers evaluate contaminants in community garden soils in New York City

Researchers reveal new technique to grow human hepatocytes in the laboratory

New test can detect drug abuse faster

Scientists show evidence for exchange of lactate between different brain cells

Role of biomarkers in drug development and regulatory decision making

Lead exposure in early childhood increases risk for sleep problems in later childhood

New computational method helps predict adverse drug reaction better than traditional computing methods

Pittcon will exhibit at the Bioconference clinical diagnostics and research virtual conference

Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Orange pigment may have potential as anti-cancer drug

Nanodiamonds may improve outcomes for patients undergoing root canals

New research shows nicotine increases codeine-induced analgesia

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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