Toxicology News and Research

Latest Toxicology News and Research

Thermo Fisher launches innovations that enable customers to improve lab productivity

Thermo Fisher Scientific Inc., the world leader in serving science, today introduced innovations that enable customers to improve laboratory productivity - by delivering results faster and with greater accuracy - while extending the boundaries of routine analysis. During Pittcon, being held from March 11-15, in Orlando, the company will showcase its scale and depth of capabilities across its three premier brands: Thermo Scientific, Fisher Scientific and Unity Lab Services.

From Thermo Fisher Scientific Inc. 13 Mar 2012

DNDi commences Oxaborole SCYX-7158 Phase I clinical trial for sleeping sickness

The Drugs for Neglected Diseases initiative (DNDi) has commenced a Phase I clinical trial in healthy adults in Paris, France, to determine the safety and tolerability of a promising oral drug candidate Oxaborole SCYX-7158, to treat human African trypanosomiasis (HAT, or sleeping sickness) for stage 1 and stage 2 of the disease.

12 Mar 2012

AB SCIEX introduces new triple quadrupole mass spectrometry instrumentation system

AB SCIEX, a global leader in life science analytical technologies, today announced the introduction of the AB SCIEX 4500 series, which is next-generation, mass spectrometry instrumentation that sets a new benchmark for routine quantitation and screening.

12 Mar 2012

AB SCIEX announces commercial expansion in Brazil

AB SCIEX, a global leader in life science analytical technologies, today announced its expansion of commercial operations in Brazil to support the Brazilian scientific community's increasing use of mass spectrometry for food safety testing, environmental analysis, academic research, drug development, forensic toxicology and clinical research.

12 Mar 2012

OSU researchers use carbon nanotubes to increase the speed of biological sensors

Researchers at Oregon State University have tapped into the extraordinary power of carbon "nanotubes" to increase the speed of biological sensors, a technology that might one day allow a doctor to routinely perform lab tests in minutes, speeding diagnosis and treatment while reducing costs.

12 Mar 2012

First 'theranostic' agent for treatment of ALL

A team of researchers at Case Western Reserve University School of Medicine has developed the first "theranostic" agent for the treatment of acute lymphoblastic leukemia (ALL).

8 Mar 2012

MTPC, Medicago partner to develop and commercialize three new vaccines

Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), today announced the establishment of a strategic alliance with Mitsubishi Tanabe Pharma Corporation (MTPC) through the execution of a Master Research Collaboration Agreement.

6 Mar 2012

Diesel exhaust fumes linked to lung cancer among miners

It has been known that diesel exhaust may be a probable carcinogen. But the 20-year study from the National Cancer Institute took a closer look in the Diesel Exhaust in Miners Study, which followed 12,315 miners working in eight underground nonmetal mining facilities. Data were collected on the miners' health and exposure to various elements and chemicals from the time when the mine company first introduced diesel-powered equipment (between 1947 and 1967) until the end of the study in 1997. They breathed varying levels of exhaust from diesel-powered equipment, levels higher than the general population encounters.

4 Mar 2012

Induced hyperammonaemia increases daytime sleepiness in patients with cirrhosis

Italian and Swiss researchers confirm that induced hyperammonaemia significantly increases daytime sleepiness in patients with cirrhosis. The findings available in the March issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, show that higher blood levels of ammonia reduced the ability of cirrhotic patients to produce restorative sleep.

2 Mar 2012

Loss of STAT1 transcription factor causes breast cancer development

Breast cancer represents about a fifth of all cancers diagnosed in women. The reasons for the rapid progression of the disease remain relatively poorly understood but recent work in the group of Veronika Sexl at the University of Veterinary Medicine, Vienna has pointed the finger strongly at loss or inactivation of the transcription factor STAT1.

1 Mar 2012

EpiCept fourth quarter revenue decreases to $0.2 million

EpiCept Corporation today announced operating and financial results for the fourth quarter and full year ended December 31, 2011, and provided an update on the Company's key business initiatives.

29 Feb 2012

AB SCIEX granted ISO 13485 certification for quality management system.

AB SCIEX, a global leader in life science analytical technologies, today announced that it has achieved ISO 13485 certification for its quality management system. ISO 13485 is an international standard that requires a manufacturer to demonstrate a comprehensive and compliant quality management system suitable for the design and manufacturing of medical devices.

27 Feb 2012

Insight into relationship between two types of suppressors in cancerous tumors

The University of Kentucky has announced that Dr. Daret St. Clair, the James Graham Brown Endowed Chair and professor of toxicology, has published the first comprehensive study that provides insight into the relationship between two types of suppressors in cancerous tumors. The results will enhance the understanding of transcriptional mechanisms in carcinogenesis.

23 Feb 2012

UMMS' iHeal project uses emerging technologies to detect drug cravings and intervene

Clinical researchers at the University of Massachusetts Medical School (UMMS) are combining an innovative constellation of technologies such as artificial intelligence, smartphone programming, biosensors and wireless connectivity to develop a device designed to detect physiological stressors associated with drug cravings and respond with user-tailored behavioral interventions that prevent substance use.

22 Feb 2012

SOT 51st Annual Meeting and ToxExpo to be held March 11-15

The Society of Toxicology (SOT) 51st Annual Meeting and ToxExpo - the largest meeting and expo of its kind anywhere in the world - will take place from March 11-15. The five-day program will feature more than 180 sessions, presenting the latest research findings and recommendations for remedial action on a wide range of issues affecting human and animal health and the environment.

22 Feb 2012

Some answers about prescription psychiatric drugs

The circumstances of Whitney Houston's demise have dominated headlines and search trends since news outlets first reported of her death. Her struggle with addiction was covered extensively by the media, and even discussed candidly by Houston herself during several high-profile interviews.

20 Feb 2012

Arsenic found in baby formula containing organic brown rice syrup

Rice is among the plants that are efficient in taking up arsenic from the soil, environmental chemist Brian Jackson of Dartmouth College in Hanover, N.H., and his co-authors said in Thursday's issue of the journal Environmental Health Perspectives. Long-term exposure to extremely high levels of inorganic arsenic can increase the risk of lung, liver and bladder cancer as well as miscarriage and infertility.

18 Feb 2012

TRANSFUSION publishes positive results from CryoStor collaborative research

BioLife Solutions, Inc., a leading developer, manufacturer and marketer of proprietary clinical grade hypothermic storage and cryopreservation freeze media for cells and tissues, today announced that TRANSFUSION, the foremost publication in the world for new information regarding transfusion medicine, has published a peer-reviewed journal article reporting positive results of collaborative research on CryoStor, BioLife's serum-free, protein-free cryopreservation freeze media.

18 Feb 2012

Pharmos reports net loss of $0.4 million for fourth quarter 2011

Pharmos Corporation reported financial results for the fourth quarter and twelve-month period ended December 31, 2011. These results are included in the Company's Yearly Report on Form 10-K which has been filed with the SEC.

17 Feb 2012

Collaborative Cross can help fast-track key discoveries about genetics and disease

A series of 15 scientific papers published this week in the journals of the Genetics Society of America (Genetics and G3: Genes|Genomes|Genetics) put North Carolina at the epicenter of a scientific resource called the Collaborative Cross - a "library" of genetic diversity that scientists believe can help fast-track important discoveries about genetics and disease into new discoveries, tests, and treatments that impact human health.

17 Feb 2012