Toxicology News and Research

Latest Toxicology News and Research

Exposure to common flame retardant may affect fertility and long-term memory

Mice genetically engineered to be susceptible to autism-like behaviors that were exposed to a common flame retardant were less fertile and their offspring were smaller, less sociable and demonstrated marked deficits in learning and long-term memory when compared with the offspring of normal unexposed mice, a study by researchers at UC Davis has found.

16 Feb 2012

BioCryst fourth quarter revenues decrease to $5.2 million

BioCryst Pharmaceuticals, Inc. announced financial results for the fourth quarter and full year ended December 31, 2011.

16 Feb 2012

Air pollution raises risk of stroke and cognitive decline

According to data from two studies published in the Archives of Internal Medicine exposure to air pollution may have serious cognitive and cardiovascular health consequences, even at levels currently deemed acceptable by the U.S. Environmental Protection Agency (EPA).

15 Feb 2012

400 lipsticks found to contain too much lead and could be harmful

Reuters first reported that a new study conducted by the FDA found that 400 lipsticks on the market tested positive for lead, according to the Campaign for Safe Cosmetics, a coalition that advocates for safer cosmetics and hygiene products.

15 Feb 2012

Karo Bio decides to discontinue development program for eprotirome

Karo Bio AB (publ) has decided to discontinue the development program for eprotirome after an animal study has demonstrated unwanted effects following long-term exposure. The planned spin-off of the preclinical part of operations will not proceed.

14 Feb 2012

Marshall University researcher to understand connections between cancer and obesity

A Marshall University researcher has been awarded a one-year, $60,000 grant from the Pharmaceutical Research and Manufacturers of America (PhRMA) Foundation.

14 Feb 2012

New iHeal project aims to detect drug cravings and prevent medication use

Imagine a device combining sensors to measure physiological changes. Then imagine a smartphone with software applications designed to respond to your bodily changes in an attempt to change your behavior. That is the vision behind "iHeal," currently being developed- by Edward Boyer from the University of Massachusetts Medical School in the US, and his colleagues.

9 Feb 2012

EpiCept seeks FDA Fast Track designation for AmiKet to treat CIPN

EpiCept Corporation today announced that it has filed for Fast Track designation for AmiKet(amitriptyline 4%, ketamine 2% cream) for the treatment for chemotherapy-induced peripheral neuropathy (CIPN) with the U.S. Food and Drug Administration.

7 Feb 2012

Pediatricians lead statewide effort to raise awareness about childhood vaccination

Two Saint Louis University pediatricians are leading a Missouri State Medical Association statewide effort to change the way doctors respond to parents' fears of vaccines, and to raise awareness about the importance of getting children vaccinated.

3 Feb 2012

Multiple DNA repair defect in monocytes

Scientists working with Professor Bernd Kaina of the Institute of Toxicology at the Medical Center of Johannes Gutenberg University Mainz have demonstrated for the first time that certain cells circulating in human blood - so-called monocytes - are extremely sensitive to reactive oxygen species (ROS).

3 Feb 2012

Researchers identify mechanism that leads to ischemia-reperfusion damage

For patients with incurable pulmonary conditions, a lung transplantation is the only available treatment option. However, suitable donor organs are scarce, and even getting them to prospective recipients is not easy. As Professor Alexander Dietrich of the Walther Straub Institute of Pharmacology and Toxicology at LMU explains, "An isolated lung which is no longer perfused with blood can become so severely damaged that it is no longer functional. This so-called ischemia-reperfusion injury is one of the major problems in the field of lung transplantation."

2 Feb 2012

Sigma-Aldrich acquires BioReliance

Sigma-Aldrich Corporation, a leading Life Science and High Technology company, announced it has completed its acquisition of BioReliance Holdings, Inc., a leading provider of global biopharmaceutical testing services, from Avista Capital Partners for $350 million in cash, subject to normal post-closing adjustments.

31 Jan 2012

Mystery teen neurological illness followed up by Erin Brockovich meets resistance

Famous environmental activist Erin Brockovich’s team faced resistance as they tried to test the area around an upstate New York school for clues to a case involving more than a dozen teens plagued by mysterious Tourette's-like symptoms and seizures. One neurologist who has seen most of the affected girls has diagnosed their illness as psychological in origin, but some parents and members of the community have disputed that diagnosis.

30 Jan 2012

BGSU chemist uses supercomputer to help unlock benefits of toxic bacteria

Blue-green algae is causing havoc in Midwestern lakes saturated with agricultural run-off, but researchers in a northwest Ohio lab are using supercomputers to study a closely related strain of the toxic cyanobacteria to harness its beneficial properties.

26 Jan 2012

Chemicals in packaged food and textiles linked to low immunity in kids: Study

According to researchers children exposed to chemicals from food packaging and textile products may have compromised immune systems. They found kids with more perfluorinated compounds, or PFCs, in their blood stream were less likely to respond to routine vaccines.

26 Jan 2012

Society of Toxicology 51st Annual Meeting and ToxExpo to be held March 11-15

More than 7,000 toxicologists from every corner of the globe are expected to attend the Society of Toxicology (SOT) 51st Annual Meeting and ToxExpo-, which will highlight toxicology's crucial role in creating a safer and healthier world. The five-day meeting will take place at the Moscone Convention Center in San Francisco from March 11-15, 2012.

25 Jan 2012

CQA derivatives in mate tea kill human colon cancer cells

Could preventing colon cancer be as simple as developing a taste for yerba mate tea? In a recent University of Illinois study, scientists showed that human colon cancer cells die when they are exposed to the approximate number of bioactive compounds present in one cup of this brew, which has long been consumed in South America for its medicinal properties.

24 Jan 2012

Bioengineers receive $2 million NIH grant to develop new toxicology tests

Chemicals in pharmaceutical drugs can obviously save lives. But as more and stronger chemicals have been introduced, our basic knowledge of the broader health impact of all these chemicals has not kept up with the rapid pace of innovation. There is exceptionally little information on how chemicals in our drugs and also in the environment around us, including on the food we eat, impact some of the most important cells in our body: stem cells. Without basic knowledge and tests on the impact of chemicals on our stem cells, we may be unwittingly damaging essential regenerative functions in our body.

18 Jan 2012

Animal study confirms dramatic effects of natural formula against prostate cancer

New animal study confirms the dramatic effects of a natural formula against aggressive prostate cancer tumors. Researchers at the Methodist Research Institute at Indiana University conducted the study on mice, using a human prostate cancer xenograft model.

17 Jan 2012

Links between deodorants and breast cancer refuted but more information needed: Study

A chemical present in cosmetics, food products and pharmaceuticals has been found in tissue samples from 40 women with breast cancer. A number of studies since 1998 have raised concerns about the potential role of these chemicals called parabens in breast cancer as they possess estrogenic properties. Estrogen is known to play a central role in the development, growth and progression of breast cancer.

16 Jan 2012