Toxicology News and Research

Latest Toxicology News and Research

Comprehensive ADMESeq Research Screening Panel launched

RainDance Technologies, Inc., the Digital Biology Company, and Ambry Genetics, today announced the launch of a comprehensive targeted sequencing panel to screen genes involved with drug absorption, distribution, metabolism, and excretion (ADME) research. The ADMESeq Research Screening Panel enables researchers to simultaneously interrogate 242 known pharmacogenetic genes using next-generation sequencing (NGS) systems.

24 Oct 2011

Covance Shanghai facility receives OECD Good Laboratory Practice certification

Covance Inc. today announced that its early development facility located in Shanghai, China, has received Good Laboratory Practice (GLP) certification from the Belgian GLP Monitoring Authority, a member of the Organization for Economic Cooperation and Development (OECD). The Covance facility in Shanghai provides bioanalytical, toxicology, lead optimization toxicology, in-vivo PK screening, and metabolism services.

24 Oct 2011

First step in the development of new drug combinations against diseases, conditions

The researchers found a way of identifying ideal drug combinations from billions of others which would prevent inflammation from occurring.

From The University of Manchester 24 Oct 2011

New metabolic pathway for controlling brain inflammation

A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.

21 Oct 2011

JHU, Eisai enter drug-discovery research collaboration for brain disorders

The Johns Hopkins University (JHU) has entered into a drug-discovery research collaboration with Eisai, a pharmaceutical company based in Tokyo, to develop proprietary small-molecule drugs for a range of brain conditions such as schizophrenia, pain, brain tumors and Alzheimer's disease.

20 Oct 2011

Potential new protein target for pulmonary hypertension

A protein critical to development appears to have a grave impact on lungs exposed to smoking and air pollution, researchers report.

18 Oct 2011

FDA may be lax when it comes to laws on sea food safety: Study

Due to the last year’s BP oil spill in the Gulf of Mexico, a new study contends that current federal standards underestimate the risk to pregnant women and children of cancer-causing contaminants that can accumulate in seafood from such spills.

16 Oct 2011

Brain stem cell treatment for multiple sclerosis

The prospect of doing human clinical trials with stem cells to treat diseases like multiple sclerosis may be growing closer, say scientists at the University at Buffalo and the University at Rochester, who have developed a more precise way to isolate stem cells that will make myelin.

15 Oct 2011

Scientists characterize and isolate potential stem cells to treat MS, myelin disorders

Scientists have improved upon their own previous world-best efforts to pluck out just the right stem cells to address the brain problem at the core of multiple sclerosis and a large number of rare, fatal children's diseases.

14 Oct 2011

Study explores link between BPA exposure and breast cancer

Chronic low-level exposure to a compound found in a variety of plastic household items could pose a threat to women who overproduce a protein linked with breast cancer, say researchers at University of Alabama at Birmingham.

13 Oct 2011

FDA grants Advaxis pre-IND meeting for ADXS-HER2 cancer immunotherapy

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has been granted a pre-Investigational New Drug meeting with the U.S. Food and Drug Administration on November 22nd, 2011 to discuss the initial clinical development plan for ADXS-HER2, a construct for the treatment of HER2 expressing cancers.

12 Oct 2011

AIT Laboratories introduces new suite of services for prescription compliance monitoring

Chronic pain affects an estimated 116 million adults in the U.S.—more than the number affected by heart disease, diabetes, and cancer combined, according to a recent report by the Institute of Medicine.

10 Oct 2011

VGX International, Inovio partner to co-develop SynCon vaccines for hepatitis B and C infections

Inovio Pharmaceuticals, Inc., a leader in the development of synthetic vaccines against cancers and infectious diseases, announced today that it has entered into a product development collaboration agreement with its affiliate, VGX International Inc., to co-develop Inovio's SynCon therapeutic vaccines for hepatitis B and C infections.

10 Oct 2011

University of Leicester's public lectures to explore reality of toxic damage

The genetic and biochemical consequences of exposure to toxins and mutagens are the theme of the next in a series of accessible lecture events at the University of Leicester.

7 Oct 2011

Tips on how to prevent unnecessary medication/supplement mishaps

Navigating the supplement and medication maze can get confusing especially when you have multiple prescriptions. It is important to organize yourself with your medications and supplements to prevent unnecessary mishaps.

7 Oct 2011

USDTL releases CordStat EtOH assay screens for newborn alcohol exposure in utero

United States Drug Testing Laboratories (USDTL), a reference laboratory specializing in alcohol and drugs of abuse testing, released a new assay testing umbilical cord for newborn alcohol exposure in utero on Monday, October 3, 2011.

3 Oct 2011

ViroPharma licenses worldwide rights from Intellect Neurosciences to OX1 for treatment of FA

ViroPharma Incorporated today announced the license of worldwide rights from Intellect Neurosciences, Inc. to its clinical stage drug candidate, OX1, being developed for the treatment of Friedreich's Ataxia (FA), a rare, hereditary, progressive neurodegenerative disease.

1 Oct 2011

Circadian subsidiary submits IND application to FDA to initiate VGX-100 study against cancer

Circadian Technologies Limited is extremely proud to announce that its 100% owned subsidiary, Vegenics Pty Ltd, has submitted an investigational new drug application to the U.S. Food and Drug Administration to initiate clinical studies of VGX-100.

1 Oct 2011

Circadian files IND with FDA for VGX-100 for the treatment of cancer patients with solid tumors

Circadian Technologies Limited (ASX: CIR, OTCQX:CKDXY) is extremely proud to announce that its 100% owned subsidiary, Vegenics Pty Ltd, has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) to initiate clinical studies of VGX-100. The first trial (Phase I) will involve the treatment of a variety of different cancer types in patients with late stage cancer.

29 Sep 2011

InterMune reports new data from Esbriet clinical trial on IPF

InterMune, Inc. today reported that new data was presented at the European Respiratory Society (ERS) Annual Congress supporting the longer-term safety and tolerability of Esbriet(pirfenidone) in patients with idiopathic pulmonary fibrosis (IPF), a devastating lung disease.

26 Sep 2011

Toxicology News and Research

Latest Toxicology News and Research

Comprehensive ADMESeq Research Screening Panel launched

Covance Shanghai facility receives OECD Good Laboratory Practice certification

First step in the development of new drug combinations against diseases, conditions

New metabolic pathway for controlling brain inflammation

JHU, Eisai enter drug-discovery research collaboration for brain disorders

Potential new protein target for pulmonary hypertension

FDA may be lax when it comes to laws on sea food safety: Study

Brain stem cell treatment for multiple sclerosis

Scientists characterize and isolate potential stem cells to treat MS, myelin disorders

Study explores link between BPA exposure and breast cancer

FDA grants Advaxis pre-IND meeting for ADXS-HER2 cancer immunotherapy

AIT Laboratories introduces new suite of services for prescription compliance monitoring

VGX International, Inovio partner to co-develop SynCon vaccines for hepatitis B and C infections

University of Leicester's public lectures to explore reality of toxic damage

Tips on how to prevent unnecessary medication/supplement mishaps

USDTL releases CordStat EtOH assay screens for newborn alcohol exposure in utero

ViroPharma licenses worldwide rights from Intellect Neurosciences to OX1 for treatment of FA

Circadian subsidiary submits IND application to FDA to initiate VGX-100 study against cancer

Circadian files IND with FDA for VGX-100 for the treatment of cancer patients with solid tumors

InterMune reports new data from Esbriet clinical trial on IPF

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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