Tuberculosis News and Research

Latest Tuberculosis News and Research

How pathogens are controlled under hypoxic conditions

Infected tissue has a low concentration of oxygen. The body's standard immune mechanisms, which rely on oxygen, can then only function to a limited extent.

24 May 2019

Study reveals a better way to help increase support for vaccinations

The re-introduction of measles, mumps and other previously eradicated diseases to the United States is nothing short of a public health crisis. Since Jan. 1, a staggering 880 individual cases of measles have been confirmed in 24 states -- the greatest number of cases since 1994. Measles was declared eliminated in the U.S. in 2000.

23 May 2019

HIV treatment via community-based clubs can reduce retention of patients in care, study finds

Delivery of antiretroviral HIV treatment via community-based clubs can reduce retention of patients in care, according to a new research study published in the open-access journal PLOS Medicine by Colleen Hanrahan of the Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland and colleagues.

22 May 2019

Virtual clinical trial: Improving methadone dosage for drug users with TB to prevent withdrawal symptoms

Drug users on methadone programs who contract tuberculosis should receive effective treatment while maintaining the correct level of methadone in their bodies, following a virtual clinical trial by pharmacy researchers at Aston University in partnership with drugs charity Addaction.

21 May 2019

Marine natural compounds could be potential treatments for triple negative breast cancer

The oceans cover more than 70 percent of the earth's surface and provide a rich source of unique, bioactive natural products.

17 May 2019

New approach to identify faster, more effective TB drug treatment regimens

Tuberculosis is a potentially deadly though curable disease. Each year about 10 million people develop active cases, and 1.6 million people die. In addition, about 1.7 billion people around the world are infected with TB bacteria, which can lie dormant for weeks to years, then become active and cause disease in up to 10 percent of those who are infected.

15 May 2019

New machine-learning approach discovers mechanism that helps antibiotics kill bacteria

Most antibiotics work by interfering with critical functions such as DNA replication or construction of the bacterial cell wall.

10 May 2019

Researchers identify genetic component involved in development of familial sarcoidosis

Working with their colleagues from the University of Lyon, researchers from MedUni Vienna's Center for Pathobiochemistry and Genetics have discovered mutations in genes that regulate the metabolic sensor mTOR in patients with familial sarcoidosis.

8 May 2019

Researchers win $6.2 million grant to study HIV/TB co-infection in children

About a third of us are walking around with the bacteria that causes tuberculosis in our bodies, but most don't actually end up with TB. For children living with HIV - about 2 million at last estimate - it's a different story.

1 May 2019

United Nations sounds alarm bell on drug-resistant infections

According to a new report from a United Nations Committee, antibiotic resistance levels are at an all time high and are the reason behind common infections becoming difficult to treat.

30 Apr 2019

New approach could simplify identification of transport proteins in mycobacteria

A team headed by Dr. Claudia Jessen-Trefzer of the University of Freiburg's Institute for Pharmaceuticals Sciences has for the first time identified a transport protein in mycobacteria which is responsible for the uptake of the nutrient L-arabinofuranose.

30 Apr 2019

New intervention improves healthy behavior among South African adolescents, study finds

In Sub-Saharan Africa, the leading causes of death are changing. Fewer people are dying of infectious diseases like malaria or tuberculosis, but non-communicable diseases, including heart disease and diabetes, are on the rise.

27 Apr 2019

Huge Malaria vaccine trial in Malawi

This week the African nation of Malawi became one of the first of the planned three to launch a pilot trial for a novel vaccine against malaria. The news and the efforts were lauded by the World Health Organization (WHO).

24 Apr 2019

Pregnant women with type 1 diabetes are at greater risk of preterm birth

Pregnant women with type 1 diabetes are at increased risk of delivering their baby prematurely. The risk increases as blood sugar levels rise, however women who maintain the recommended levels also risk giving birth prematurely.

23 Apr 2019

Key research takeaways from ECCMID 2019

This article aims to provide a brief overview of the key themes of the 29th ECCMID conference and update readers on current research projects.

From ESCMID 19 Apr 2019

Researchers discover new broad-spectrum antibiotic that contains arsenic

Antibiotic resistance has been called one of the biggest public health threats of our time. There is a pressing need for new and novel antibiotics to combat the rise in antibiotic-resistant bacteria worldwide.

16 Apr 2019

Novel models and strategies for TB detection, elimination, and care

This week, publication of a special issue on tuberculosis begins in PLOS Medicine, advised by guest editors Richard Chaisson of Johns Hopkins University, Claudia Denkinger of the University of Heidelberg, and Mark Hatherill of the South African Tuberculosis Vaccine Institute.

8 Apr 2019

Promising new way to thwart tricky Mtb pathogen

Tuberculosis, an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective.

29 Mar 2019

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

The U.S. Food and Drug Administration today approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation. This is the first time that the FDA has approved a treatment for nr-axSpA.

28 Mar 2019

Autophagy can help combat Salmonella and other pathogens

Autophagy - the process of recycling cellular material in the body, can help combat Salmonella and other pathogens according to researchers at the School of Life Sciences, University of Warwick who have studied how autophagy can get rid of bacteria, and prevent diseases developing.

27 Mar 2019