Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

New clinical trial to test possible therapeutics for COVID-19 in hospitalized patients

The Clinical Trials Network of Tennessee (CTN2) at the University of Tennessee Health Science Center has contracted a new clinical trial to test possible therapeutics for COVID-19 in hospitalized patients. This new trial brings the total generated by CTN2 contracts for the university to nearly $7 million.

12 May 2021

Patient support program for painful conditions may also help avoid use of risky opioids

A program that provides ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.

6 May 2021

Study describes IgG antibodies in Crohn's disease specific for human bacterial flagellins

Last year, Charles O. Elson, M.D., demonstrated a potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease. He used a mouse model that included immune-reactive T cells from patients with Crohn's disease in a flagellin peptide-specific immunotherapy.

6 May 2021

Artificial super stool may be a game-changer in the treatment of chronic gut infections

The urgent need for human stool donations to treat chronic gut infections could soon be eased with innovative research to develop artificial super stool.

28 Apr 2021

Commonly-prescribed drug for IBD blunts COVID-19 vaccine response

People who take a commonly-prescribed drug for inflammatory bowel disease (IBD) should not assume they are protected after a first dose of COVID-19 vaccine, after a large-scale study found many had poor antibody responses.

26 Apr 2021

Defects in specific goblet cells may be a factor contributing to ulcerative colitis

There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg.

19 Apr 2021

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

The gut is a well-established route of infection and target for viral damage by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent for COVID-19. This is supported by the clinical observation that about half of COVID-19 patients exhibit gastrointestinal (GI) symptoms.

8 Apr 2021

Infliximab may hinder the effectiveness of some COVID-19 vaccines

A new study reports reduced vaccine efficacy following the use of a single COVID-19 vaccine dose in people who are on the immunosuppressive monoclonal antibody Infliximab.

31 Mar 2021

New study may shed light on inflammatory bowel disease

Researchers have found an unexpected synergy between a T-cell stimulatory protein -- the ICOS ligand -- and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice.

26 Mar 2021

DNMT3a plays a key role in regulating HSC responses to infections

Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections.

26 Mar 2021

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

In African Americans, the genetic risk landscape for inflammatory bowel disease (IBD) is very different from that of people with European ancestry, according to results of the first whole-genome study of IBD in African Americans.

20 Feb 2021

Nanotherapy shows potential for treating severe Crohn's disease

Scientists from the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn's disease.

17 Feb 2021

Inherited genetic variation may affect the response to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer.

10 Feb 2021

Novel method instructs immune cells to help repair damaged tissues in the intestine

A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University.

8 Feb 2021

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

A healthy person has a general balance of good and bad bacteria. But that balance is thrown off when someone gets sick.

5 Feb 2021

New partnership to develop test for predicting disease course in pediatric Crohn's patients

The Crohn's & Colitis Foundation, the leading non-profit organization focused on both research and patient support for inflammatory bowel disease (IBD), has entered into a partnership with LifeArc, an independent medical research charity that advances translation of early science into health care treatments or diagnostics, to potentially develop the first clinical lab test to predict disease course in pediatric patients with Crohn's disease and response to treatment.

25 Jan 2021

Researchers develop a novel, patient-derived model of ulcerative colitis

As reported in Nature Communications, researchers from Cleveland Clinic's Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease.

11 Jan 2021

Polygenic risk scores from multi-population data could improve IBD predictions

Using genetic data from nearly 30,000 people, Mount Sinai researchers have built risk scores from a combination of datasets representing distinct ancestral populations that improve prediction of risk for inflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis. The study was published in Gastroenterology on December 24.

24 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Could number two be number one when it comes to combating recurrent Clostridium difficile (CDI) infections?Using genetic material analysis and machine learning, UBC researchers have pinpointed several key factors to ensure successful fecal microbiota transplants (FMT), which have proven successful in treating bacterial infections in the gut including illnesses like C. difficile, Crohn's Disease, Colitis and even obesity, explains lead author Negin Kazemian.

10 Dec 2020

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

New clinical trial to test possible therapeutics for COVID-19 in hospitalized patients

Patient support program for painful conditions may also help avoid use of risky opioids

Study describes IgG antibodies in Crohn's disease specific for human bacterial flagellins

Artificial super stool may be a game-changer in the treatment of chronic gut infections

Commonly-prescribed drug for IBD blunts COVID-19 vaccine response

Defects in specific goblet cells may be a factor contributing to ulcerative colitis

Leaky gut and microbial dysbiosis could contribute to cytokine storm in severely ill COVID-19 cases

Infliximab may hinder the effectiveness of some COVID-19 vaccines

New study may shed light on inflammatory bowel disease

DNMT3a plays a key role in regulating HSC responses to infections

Whole-genome study of IBD in African Americans reveals a different genetic risk landscape

Nanotherapy shows potential for treating severe Crohn's disease

Inherited genetic variation may affect the response to cancer immunotherapy

Novel method instructs immune cells to help repair damaged tissues in the intestine

New diagnostic imaging tool measures naturally occurring enzymes in the gastrointestinal tract

New partnership to develop test for predicting disease course in pediatric Crohn's patients

Researchers develop a novel, patient-derived model of ulcerative colitis

Polygenic risk scores from multi-population data could improve IBD predictions

Researchers demonstrate potential preventive treatment for Crohn's disease

Researchers pinpoint key factors to ensure successful fecal microbiota transplants

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Newsletters you may be interested in