Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Study identifies genetic risk for fatal blood clots in IBD patients

Blood clots are the biggest cause of death in patients with inflammatory bowel disease (IBD) ─ ulcerative colitis or Crohn's disease. In a retrospective study recently published in the journal Gastroenterology, Cedars-Sinai investigators found that a combination of rare and common genetic variants in some IBD patients significantly increased their risk of developing clot-causing thromboembolic diseases.

11 Nov 2020

Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

New research presented at ACR Convergence, the American College Rheumatology's annual meeting, showed that patients with rheumatic diseases whose infliximab treatment was individually assessed and adjusted with a new strategy called therapeutic drug monitoring did not achieve remission at higher rates compared to those who received standard care.

8 Nov 2020

New IBD safety registry established to support the completion of post-marketing safety requirements

The Pediatric IBD Foundation, ImproveCareNow, and the Critical Path Institute (C-Path) are proud to announce a collaboration establishing the Children's Registry for the Advancement of Therapeutics (CREATE™).

6 Nov 2020

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies, researchers at Children's Hospital of Philadelphia have found significant genetic correlations between inflammatory bowel disease and stress and depression.

29 Oct 2020

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

Bacteria from the mouth could hold clues to understanding – and potentially treating – severe ulcerative colitis, a painful bowel disease.

29 Oct 2020

People with depression are more likely to develop Crohn's disease

A new study, published inGut, has found depression is more common among people with Crohn's disease or ulcerative colitis in the years before they are diagnosed with these bowel conditions.

28 Oct 2020

Readers and tweeters shed light on vaccine trials and bias in health care

In the piece about the AstraZeneca vaccine trial subject who suffered severe spinal cord inflammation, that person was repeatedly referred to as a "patient" ("NIH 'Very Concerned' About Serious Side Effect in Coronavirus Vaccine Trial," Sept. 14).

28 Oct 2020

Intestinal microbiota offers new prospects for treating celiac disease

Celiac disease is an immune disease of the intestine that affects more than 1% of the population. It is characterised by gluten intolerance that causes inflammation of the gut, abdominal pain and diarrhoea, and can lead to weight loss and deficiencies among patients.

23 Oct 2020

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

People with celiac disease may find themselves more comfortable with extra Thanksgiving turkey dinners.An international team of researchers led by McMaster University has found that tryptophan, an amino acid present in high amounts in turkey, along with some probiotics, may help them heal and respond better to a gluten-free diet.

22 Oct 2020

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

In many patients with Crohn's disease, abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to "creep" through the abdomen and wrap around the intestines of many patients with this inflammatory bowel disease (IBD) has been an enduring mystery.

1 Oct 2020

Study shows tofacitinib drug can repair permeability defects in the intestine

A team of researchers led by biomedical scientist Declan F. McCole at the University of California, Riverside, has found that the drug tofacitinib, also called Xeljanz and approved by the FDA to treat rheumatoid arthritis and ulcerative colitis, can repair permeability defects in the intestine.

30 Sep 2020

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

University of Texas at Dallas researchers have designed a wearable device that monitors sweat for biomarkers that could signal flare-ups of inflammatory bowel disease (IBD).

28 Sep 2020

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

The research by the UPV/EHU-University of the Basque Country, in collaboration with Harvard University, has yielded highly encouraging results, and studies in animal models have already begun

28 Sep 2020

Treatment with a cannabinoid prevented the development of colon cancers in mice

Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are caused by unrestrained inflammation of the gastrointestinal tract.

15 Sep 2020

Study shows lack knowledge about colonoscopy among high-risk patients

Colorectal cancer is the third most common cause of cancer deaths in the United States and advanced colorectal polyps are a major risk factor.

14 Sep 2020

Scientists discover tissue reparative role for a rare immune cell type in the gut

Scientists from King's College London have discovered an unexpected tissue reparative role for a rare immune cell type in the gut that could tip toward fibrosis or cancer if dysregulated.

8 Sep 2020

Lasting nature of IBD linked to a long-lived immune cell that provokes damaging inflammation

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide.

24 Aug 2020

Researchers identify a useful biomarker for intestinal diseases

Enzymes used by bacteria to break down mucus in the gut could provide a useful biomarker for intestinal diseases, according to new research published in Nature Communications.

11 Aug 2020

New computational model can help determine drug viability

About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn's disease, end up becoming resistant or unresponsive to it.

5 Aug 2020

Finding the right treatment for people with IBD may soon become easier

Finding the right treatment for people living with chronic intestinal inflammation, also known as inflammatory bowel disease, might soon be getting easier.

27 Jul 2020

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Study identifies genetic risk for fatal blood clots in IBD patients

Researchers launch clinical trial to assess therapeutic drug monitoring for patients with inflammatory diseases

New IBD safety registry established to support the completion of post-marketing safety requirements

Study suggests a role for the hypothalamus in genetic susceptibility to IBD

Severe ulcerative colitis linked to a newly-discovered strain of oral bacteria

People with depression are more likely to develop Crohn's disease

Readers and tweeters shed light on vaccine trials and bias in health care

Intestinal microbiota offers new prospects for treating celiac disease

Tryptophan found in turkeys can accelerate intestinal healing in people with celiac disease

Researchers identify pathogen responsible for creeping migration of fat in Crohn's patients

Study shows tofacitinib drug can repair permeability defects in the intestine

Wearable device tracks biomarkers in sweat associated with inflammatory bowel disease

Multifunctional cell therapy system raises hopes to treat inflammatory bowel disease

Treatment with a cannabinoid prevented the development of colon cancers in mice

Study shows lack knowledge about colonoscopy among high-risk patients

Scientists discover tissue reparative role for a rare immune cell type in the gut

Lasting nature of IBD linked to a long-lived immune cell that provokes damaging inflammation

Researchers identify a useful biomarker for intestinal diseases

New computational model can help determine drug viability

Finding the right treatment for people with IBD may soon become easier

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Ulcerative Colitis News and Research

Latest Ulcerative Colitis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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