Prostate cancer is the second most common cancer in men worldwide. However, unlike many solid tumors, a significant number of men die with the disease rather than because of it. This presents unique challenges in determining whether, when, and how to intervene to manage tumor growth and spread, balancing the goal of extending survival with preserving quality of life.
Since the previous edition of this book, the field has seen significant advancements, particularly in improving the detection and monitoring of prostate cancer. Notable developments include the evaluation of MRI for screening and PSMA-PET/CT for staging. Treatment options have also expanded and evolved across all stages of the disease, with innovations such as ultrahypofractionated radiotherapy, oral LHRH antagonists, PARP inhibitors, and lutetium-177 PSMA-617 radioligand therapy.
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