Neurodegenerative disorders are marked by a loss of neuronal structure and function, which causes issues with movement (ataxia) or mental function (dementia). These changes occur as a result of genetic mutations or protein-folding abnormalities, which can accumulate with age.
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While some pathophysiologies, such as amyloid plaques, are well understood, many of the cellular processes that cause neurodegeneration are yet to be completely elucidated.
Defects in these critical processes may be shared by multiple neurodegenerative conditions, implying that new medicines targeting one process may alleviate the advancements of several disorders.
CST has created a beginner’s introduction to the cellular mechanisms that cause neurodegeneration in diseases, including Parkinson’s disease, Alzheimer’s disease, multiple sclerosis, amyotrophic lateral sclerosis, and Huntington’s disease.
Are you wondering how to identify the various cell types that make up the central nervous system (CNS)? You can find a Cell Type Marker guide at the end of this eBook.
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