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Grant supports gene-editing research for rare metabolic diseases

A $14M grant will fund research on gene-editing therapies for rare metabolic diseases at the Perelman School of Medicine at the University of Pennsylvania (Penn) and Children's Hospital of Philadelphia (CHOP).

10 Oct 2024

Understanding the mysterious cells in the brain's visual cortex

Imagine yourself sometime in the far future aboard a routine rocket to Mars. Someone just spilled their drink. Without gravity, it collects in floating blobs that ripple right before your eyes. Now freeze.

10 Oct 2024

Decoding Cannabis: Differentiating Hemp and Marijuana

In this interview conducted at Pittcon 2024 in San Diego, Rabi Musah delves into her innovative use of DART-HRMS and chemometric analysis to differentiate between hemp and marijuana varieties of Cannabis sativa, exploring the forensic and legal implications of these findings.

From Pittcon 10 Oct 2024

Alcohol's effects on embryo development detected in late-gestation placenta

A new study led by Pr. Serge McGraw, researcher at CHU Sainte-Justine and professor at Université de Montréal, shows that the effects of alcohol exposure on an embryo prior to implantation in the uterus can be detected in the late-gestation placenta.

9 Oct 2024

First map of DNA modification in the hippocampus and prefrontal cortex created

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin -; DNA and proteins -; plays a critical role.

9 Oct 2024

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using advanced techniques like CRISPR interference to identify TE-related risk genes.

9 Oct 2024

Study reveals why paternal mitochondria must be removed during early development

It's one of the basic tenets of biology: We get our DNA from our mom and our dad.

9 Oct 2024

Combination of 14 'skinny genes' could be the key to weight loss

The secret to losing weight could all be down to a combination of 14 'skinny genes', a new study has found.

9 Oct 2024

Tiny molecule offers hope in reducing opioid side effects

Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression.

9 Oct 2024

Studying yeast could unlock new ways to make cancer cells more vulnerable

What can stressed yeast teach us about fundamental processes in the cell? A lot, according to scientists at the European Molecular Biology Laboratory (EMBL). The team studies, among other topics, how cells adapt to stress -- such as nutrient deprivation.

9 Oct 2024

Advances in technology shed light on cell function

Cells are the basic units of life — but when it comes to cells, if you think basic means simple, think again. Cells are complicated, with many millions of biochemical reactions per second seething within their confines. They also tend to be tiny, so it’s not easy to spy on their operations.

8 Oct 2024

Clonal competition assays reveal tumor cell resistance mechanisms

All cells within the same cancer are not the same. They all have genetic errors that turn them into tumor cells, but these errors are not identical.

8 Oct 2024

Breakthrough study reveals Entropic Pulling mechanism of Hsp70 chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer.

8 Oct 2024

Study identifies RNA molecule crucial for skin wound healing

A new study from Karolinska Institutet in Sweden and the Chinese Academy of Medical Sciences has identified an RNA molecule that is important for skin wound healing.

8 Oct 2024

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

Study reveals how morphogens and cell adhesion create sharp tissue boundaries

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

8 Oct 2024

Breakthrough in detecting adulteration in ginseng supplements

Rosalee Hellberg, an associate professor in Chapman University's Food Science Program, and her research team have made a significant breakthrough in the fight against adulteration in dietary supplements.

8 Oct 2024

New triple-targeting pharmacological tool developed for cancer treatment

A study led by researchers of the Institute of Biomedicine of the University of Barcelona (IBUB) has developed a new pharmacological tool capable of simultaneously administering three oligonucleotide-based drugs, each acting against a different therapeutic target within the cell.

8 Oct 2024

Harnessing natural biopolymers to develop sustainable antibacterial solutions

In a bid to combat the rising threat of antibacterial resistance, researchers from the Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), have delved into the characteristics and applications of biomass-derived antibacterial agents.

8 Oct 2024