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Harnessing natural biopolymers to develop sustainable antibacterial solutions

In a bid to combat the rising threat of antibacterial resistance, researchers from the Research Center for Biomass and Bioproducts, National Research and Innovation Agency (BRIN), have delved into the characteristics and applications of biomass-derived antibacterial agents.

8 Oct 2024

Understanding proteasome function in Trichomonas vaginalis for drug development

Researchers from IOCB Prague are furthering the understanding of how medicines work and what it takes to develop their most effective variants.

8 Oct 2024

Monmouth Scientific to showcase Sustainable Clean Air Solutions at Lab Innovations.

Join Monmouth Scientific at Lab Innovations to explore advanced clean air solutions and learn about sustainable technologies transforming laboratory practices.

From Monmouth Scientific 8 Oct 2024

Revolutionizing drug discovery with SmartCADD

Drug discovery is much like working a jigsaw puzzle. The chemical compounds behind drug molecules must be shaped to fit with the proteins in our bodies to produce therapeutic effects.

8 Oct 2024

New UCL hub to advance cancer detection with imaging tech

UCL will lead a £17 million surgical imaging hub to improve cancer detection and take part in a £12 million collaboration to help solve age and disability-related mobility issues, in a major funding award from the UKRI Engineering and Physical Sciences Research Council (EPSRC).

8 Oct 2024

Overcoming CRISPR's side effects for therapeutic applications

CRISPR is a revolutionary tool that allows scientists to precisely modify the genome and gene expression of cells in any organism. It's a reagent-;a substance that facilitates a reaction-;that combines an enzyme with a programmable RNA capable of locating specific genetic sequences. Once guided to the correct spot, the enzyme acts like a pair of scissors, cutting, replacing, or deleting sequences of DNA.

7 Oct 2024

Researchers uncover how senescent cells can both harm and heal in liver disease

Researchers developed novel genetic tools to trace, ablate, and manipulate p16^Ink4a+^ senescent cells, revealing their distinct roles in liver fibrosis and repair. Senescent macrophages promote fibrosis, while endothelial cells aid in tissue recovery.

7 Oct 2024

Single-cell genomics unveils secrets of the human microbiome

The human microbiome plays a critical role in our health, influencing everything from disease development to treatment responses.

7 Oct 2024

Researchers uncover secret to regulating the body's internal clock

Scientists from Duke-NUS Medical School and the University of California, Santa Cruz, have discovered the secret to regulating our internal clock.

7 Oct 2024

New deep-learning framework identifies non-addictive pain relief options

An estimated one in five Americans live with chronic pain and current treatment options leave much to be desired.

7 Oct 2024

Uncovering the 'needles' in the bacterial haystack

Imagine a country with a billion people, where every individual has different interests and different goals. You will never know their interests and goals until you ask them, but asking a billion people is not an easy task.

7 Oct 2024

Schizophrenia-related hallucinations linked to disrupted motor-sensory signals

Researchers identified that impaired corollary discharge (CD) and noisy efference copy (EC) in schizophrenia disrupt self-monitoring, leading to auditory hallucinations. A computational model revealed how these motor-to-sensory dysfunctions contribute to hallucinations.

6 Oct 2024

Exploring the venomous potential of marine crustaceans for drug development

Many animals use venoms for self-defense or hunting. The components of such venom, known as toxins, interfere with various physiological processes - which is also the reason why they are so interesting for the development of new pharmacological agents.

4 Oct 2024

New insights into the role of gamma-delta T cells across 33 cancer types revealed

A new study published in Cell Press reveals critical insights into the role of gamma-delta T cells across 33 cancer types, shedding light on their potential as clinical biomarkers and therapeutic targets in cancer treatment.

4 Oct 2024

New X-ray technique reveals metal ion role in antibiotic efficacy

Researchers from City St George's, University of London have used a new ultra-high precision x-ray scattering technique to unveil the location and identity of metal ions in bacteria that are crucial for antibiotics to work optimally.

4 Oct 2024

Researchers unveil complete neuronal map of fruit fly brain

Researchers map the whole brain of Drosophila melanogaster, or the fruit fly, which comprises about 140,000 neurons and over 50 million synapses.

4 Oct 2024

Cancer Research UK backs study to develop preventive ovarian cancer vaccine

In this study, the Cancer Research UK-funded scientists will establish the targets for the vaccine. They will find out which proteins on the surface of early-stage ovarian cancer cells are most strongly recognized by the immune system and how effectively the vaccine kills mini-models of ovarian cancer called organoids.

4 Oct 2024

KiNet web portal enhances study of kinase functions in cellular signaling pathways

Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These interactions play a vital role in modulating complex signaling pathways that control various cellular processes, such as cell growth, differentiation, and response to environmental stimuli.

4 Oct 2024

Understanding the brain’s process of dividing experiences into events

The moment a person steps off the street and into a restaurant-;to take just one example-;the brain mentally starts a new "chapter" of the day, a change that causes a big shift in brain activity. Shifts like this happen all day long, as people encounter new environments, like going out for lunch, attending their kid's soccer game, or settling in for a night of watching TV.

3 Oct 2024

Stem cell transplants show promise for macular hole repair in monkeys

Human stem cell transplants successfully repaired macular holes in a monkey model, researchers report October 3rd in the journal Stem Cell Reports. After transplantation, the macular holes were closed by continuous filling of the space with retinal tissue.

3 Oct 2024